(42 nodes) Canonical Wnt signaling pathway network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZCG8_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (142 aa)
	C3ZDW2_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (374 aa)
	C3ZDW4_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
	C3ZDW6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (412 aa)
	C3ZDY0_BRAFL	Uncharacterized protein. (937 aa)
	d7	FZ domain-containing protein. (111 aa)
	C3ZKK1_BRAFL	Uncharacterized protein. (1244 aa)
	C3ZLS6_BRAFL	DIX domain-containing protein. (103 aa)
	C3ZLS7_BRAFL	Uncharacterized protein. (427 aa)
	C3ZT37_BRAFL	Uncharacterized protein. (858 aa)
	Wnt7b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (347 aa)
	C3Z2P0_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	C3XPR5_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
	C3XQC6_BRAFL	Dickkopf_N domain-containing protein. (239 aa)
	C3XSH0_BRAFL	Uncharacterized protein. (298 aa)
	C3XUQ1_BRAFL	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
	C3XW39_BRAFL	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
	C3XX83_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (304 aa)
	C3XYW6_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (329 aa)
	C3Y1Z3_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (367 aa)
	C3Y2N2_BRAFL	Uncharacterized protein. (718 aa)
	C3Y6U5_BRAFL	Uncharacterized protein. (360 aa)
	C3YE67_BRAFL	Uncharacterized protein; Belongs to the tumor necrosis factor family. (180 aa)
	C3YEA5_BRAFL	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (553 aa)
	C3YES3_BRAFL	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (529 aa)
	C3YGT9_BRAFL	Uncharacterized protein. (887 aa)
	C3YJ84_BRAFL	Uncharacterized protein. (1608 aa)
	C3YPI7_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (305 aa)
	C3YV95_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (313 aa)
	C3YX49_BRAFL	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (509 aa)
	C3YYJ7_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (343 aa)
	C3YYJ8_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (376 aa)
	C3YYJ9_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (425 aa)
	C3YZ10_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (309 aa)
	C3YZ12_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (139 aa)
	C3YZ17_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (395 aa)
	C3Z3B0_BRAFL	Uncharacterized protein. (866 aa)
	C3Z5P5_BRAFL	HMG box domain-containing protein. (566 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZCG7_BRAFL	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPR5_BRAFL	C3XUQ1_BRAFL	C3XPR5	C3XUQ1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.829
C3XPR5_BRAFL	C3Y1Z3_BRAFL	C3XPR5	C3Y1Z3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.463
C3XPR5_BRAFL	C3Y6U5_BRAFL	C3XPR5	C3Y6U5	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.836
C3XPR5_BRAFL	C3YEA5_BRAFL	C3XPR5	C3YEA5	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.840
C3XPR5_BRAFL	C3YES3_BRAFL	C3XPR5	C3YES3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.850
C3XPR5_BRAFL	C3YV95_BRAFL	C3XPR5	C3YV95	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.640
C3XPR5_BRAFL	C3YX49_BRAFL	C3XPR5	C3YX49	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.531
C3XPR5_BRAFL	C3YYJ7_BRAFL	C3XPR5	C3YYJ7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
C3XPR5_BRAFL	C3YYJ8_BRAFL	C3XPR5	C3YYJ8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.623
C3XPR5_BRAFL	C3YYJ9_BRAFL	C3XPR5	C3YYJ9	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.592
C3XPR5_BRAFL	C3YZ10_BRAFL	C3XPR5	C3YZ10	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.475
C3XPR5_BRAFL	C3YZ12_BRAFL	C3XPR5	C3YZ12	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.482
C3XPR5_BRAFL	C3YZ17_BRAFL	C3XPR5	C3YZ17	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.606
C3XPR5_BRAFL	C3Z2P0_BRAFL	C3XPR5	C3Z2P0	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.646
C3XPR5_BRAFL	C3ZCG7_BRAFL	C3XPR5	C3ZCG7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.499
C3XPR5_BRAFL	C3ZCG8_BRAFL	C3XPR5	C3ZCG8	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.495
C3XPR5_BRAFL	C3ZDY0_BRAFL	C3XPR5	C3ZDY0	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.562
C3XPR5_BRAFL	C3ZLS6_BRAFL	C3XPR5	C3ZLS6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	DIX domain-containing protein.	0.521
C3XPR5_BRAFL	C3ZLS7_BRAFL	C3XPR5	C3ZLS7	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.521
C3XPR5_BRAFL	C3ZT37_BRAFL	C3XPR5	C3ZT37	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.656