(77 nodes) Vitamin B6 binding network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (467 aa)
	C3XQ11_BRAFL	PALP domain-containing protein. (321 aa)
	C3XR74_BRAFL	Aminotran_1_2 domain-containing protein. (483 aa)
	C3XR82_BRAFL	Uncharacterized protein. (472 aa)
	C3XR88_BRAFL	MOSC domain-containing protein. (329 aa)
	C3XR89_BRAFL	MOSC domain-containing protein. (329 aa)
	C3XRL1_BRAFL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (828 aa)
	C3XSQ5_BRAFL	SHMT domain-containing protein. (406 aa)
	C3XSS1_BRAFL	Uncharacterized protein. (538 aa)
	C3XSU2_BRAFL	Uncharacterized protein. (294 aa)
	C3XUB6_BRAFL	Aminotran_5 domain-containing protein. (402 aa)
	C3XUX1_BRAFL	Uncharacterized protein. (1635 aa)
	C3XWI3_BRAFL	Aminotran_1_2 domain-containing protein. (195 aa)
	C3XWS0_BRAFL	Uncharacterized protein. (424 aa)
	C3XZ52_BRAFL	AMOP domain-containing protein. (171 aa)
	C3XZE8_BRAFL	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (538 aa)
	C3Y062_BRAFL	Uncharacterized protein. (566 aa)
	C3Y0N0_BRAFL	MOSC domain-containing protein. (327 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3Y2B8_BRAFL	PALP domain-containing protein. (329 aa)
	C3Y5S8_BRAFL	Uncharacterized protein. (893 aa)
	C3Y5V7_BRAFL	Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6. (295 aa)
	C3Y6S2_BRAFL	Uncharacterized protein. (142 aa)
	C3Y6S3_BRAFL	Uncharacterized protein. (136 aa)
	C3Y6S5_BRAFL	Uncharacterized protein. (502 aa)
	C3Y9G9_BRAFL	Uncharacterized protein. (112 aa)
	C3Y9H0_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (348 aa)
	C3YAE2_BRAFL	Thr_synth_N domain-containing protein. (671 aa)
	C3YBZ9_BRAFL	Uncharacterized protein. (267 aa)
	C3YDM6_BRAFL	Protein kinase domain-containing protein. (1887 aa)
	C3YFH7_BRAFL	Uncharacterized protein. (222 aa)
	C3YFT1_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
	C3YHC7_BRAFL	Uncharacterized protein. (939 aa)
	C3YI82_BRAFL	HPPK domain-containing protein. (737 aa)
	C3YIV5_BRAFL	Aminotran_1_2 domain-containing protein. (412 aa)
	C3YJ38_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
	C3YPX4_BRAFL	Aminotran_1_2 domain-containing protein. (449 aa)
	C3YTG3_BRAFL	Uncharacterized protein. (408 aa)
	C3YWW0_BRAFL	Aminotran_1_2 domain-containing protein. (394 aa)
	C3YZ30_BRAFL	Uncharacterized protein. (562 aa)
	C3YZ31_BRAFL	Uncharacterized protein. (112 aa)
	C3YZI1_BRAFL	Aminotran_1_2 domain-containing protein. (214 aa)
	C3Z043_BRAFL	Uncharacterized protein. (164 aa)
	C3Z044_BRAFL	Uncharacterized protein. (393 aa)
	C3Z0P5_BRAFL	Uncharacterized protein. (469 aa)
	C3Z0U0_BRAFL	Phosphoserine aminotransferase. (368 aa)
	C3Z3Q2_BRAFL	MOSC domain-containing protein. (304 aa)
	C3Z4G4_BRAFL	Uncharacterized protein. (563 aa)
	C3Z7B2_BRAFL	Uncharacterized protein. (422 aa)
	C3Z7G1_BRAFL	Uncharacterized protein. (685 aa)
	C3Z7V3_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (344 aa)
	C3ZAH6_BRAFL	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
	C3ZBQ6_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
	C3ZBR3_BRAFL	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (436 aa)
	C3ZCP5_BRAFL	Uncharacterized protein. (373 aa)
	C3ZED9_BRAFL	Uncharacterized protein. (479 aa)
	C3ZFM1_BRAFL	Aminotran_1_2 domain-containing protein. (468 aa)
	C3ZG28_BRAFL	Aminotran_1_2 domain-containing protein. (431 aa)
	C3ZGY8_BRAFL	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (905 aa)
	C3ZH05_BRAFL	Uncharacterized protein. (525 aa)
	C3ZIS1_BRAFL	Uncharacterized protein. (316 aa)
	C3ZIX7_BRAFL	PALP domain-containing protein. (324 aa)
	C3ZKV9_BRAFL	PALP domain-containing protein. (332 aa)
	C3ZMD6_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	C3ZMS9_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
	C3ZRR8_BRAFL	Uncharacterized protein. (489 aa)
	C3ZS18_BRAFL	Uncharacterized protein. (480 aa)
	C3ZTJ5_BRAFL	C2H2-type domain-containing protein. (676 aa)
	C3ZV83_BRAFL	Aminotran_1_2 domain-containing protein. (486 aa)
	C3ZVC9_BRAFL	Aminotran_5 domain-containing protein. (456 aa)
	C3ZWA7_BRAFL	Phos_pyr_kin domain-containing protein. (293 aa)
	C3ZWR9_BRAFL	Uncharacterized protein. (489 aa)
	C3ZXC6_BRAFL	Uncharacterized protein. (549 aa)
	C3ZZ27_BRAFL	Uncharacterized protein. (484 aa)
	C3ZZF6_BRAFL	Uncharacterized protein. (1318 aa)
	C3ZZL9_BRAFL	Aspartate aminotransferase. (387 aa)
	C4A130_BRAFL	Uncharacterized protein. (147 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XQ11_BRAFL	C3XR74_BRAFL	C3XQ11	C3XR74	PALP domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.817
C3XQ11_BRAFL	C3XUX1_BRAFL	C3XQ11	C3XUX1	PALP domain-containing protein.	Uncharacterized protein.	0.900
C3XQ11_BRAFL	C3XZE8_BRAFL	C3XQ11	C3XZE8	PALP domain-containing protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.936
C3XQ11_BRAFL	C3Y126_BRAFL	C3XQ11	C3Y126	PALP domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.935
C3XQ11_BRAFL	C3YAE2_BRAFL	C3XQ11	C3YAE2	PALP domain-containing protein.	Thr_synth_N domain-containing protein.	0.593
C3XQ11_BRAFL	C3ZFM1_BRAFL	C3XQ11	C3ZFM1	PALP domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.817
C3XQ11_BRAFL	C3ZIS1_BRAFL	C3XQ11	C3ZIS1	PALP domain-containing protein.	Uncharacterized protein.	0.593
C3XQ11_BRAFL	C3ZKV9_BRAFL	C3XQ11	C3ZKV9	PALP domain-containing protein.	PALP domain-containing protein.	0.902
C3XQ11_BRAFL	C3ZTJ5_BRAFL	C3XQ11	C3ZTJ5	PALP domain-containing protein.	C2H2-type domain-containing protein.	0.817
C3XR74_BRAFL	C3XQ11_BRAFL	C3XR74	C3XQ11	Aminotran_1_2 domain-containing protein.	PALP domain-containing protein.	0.817
C3XR74_BRAFL	C3XR82_BRAFL	C3XR74	C3XR82	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.546
C3XR74_BRAFL	C3XUX1_BRAFL	C3XR74	C3XUX1	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.817
C3XR74_BRAFL	C3XZE8_BRAFL	C3XR74	C3XZE8	Aminotran_1_2 domain-containing protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.829
C3XR74_BRAFL	C3Y126_BRAFL	C3XR74	C3Y126	Aminotran_1_2 domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.840
C3XR74_BRAFL	C3ZFM1_BRAFL	C3XR74	C3ZFM1	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.995
C3XR74_BRAFL	C3ZKV9_BRAFL	C3XR74	C3ZKV9	Aminotran_1_2 domain-containing protein.	PALP domain-containing protein.	0.817
C3XR74_BRAFL	C3ZTJ5_BRAFL	C3XR74	C3ZTJ5	Aminotran_1_2 domain-containing protein.	C2H2-type domain-containing protein.	0.908
C3XR82_BRAFL	C3XR74_BRAFL	C3XR82	C3XR74	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.546
C3XR82_BRAFL	C3ZFM1_BRAFL	C3XR82	C3ZFM1	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.961
C3XRL1_BRAFL	C3YIV5_BRAFL	C3XRL1	C3YIV5	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	Aminotran_1_2 domain-containing protein.	0.435