(52 nodes) Regulation of ERK1 and ERK2 cascade network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XYQ7_BRAFL	Uncharacterized protein. (1701 aa)
	C3ZPE4_BRAFL	Protein kinase domain-containing protein. (427 aa)
	C3ZPZ7_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (451 aa)
	C3ZQN0_BRAFL	J domain-containing protein. (265 aa)
	C3ZRP0_BRAFL	Roc domain-containing protein. (895 aa)
	C3ZTT7_BRAFL	FAD-binding FR-type domain-containing protein. (516 aa)
	C3ZWM2_BRAFL	Uncharacterized protein. (769 aa)
	C3ZZD3_BRAFL	Uncharacterized protein. (189 aa)
	C4A017_BRAFL	Uncharacterized protein. (205 aa)
	C4A022_BRAFL	Uncharacterized protein. (667 aa)
	C3ZKQ6_BRAFL	SCP domain-containing protein. (150 aa)
	C3ZJH5_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (294 aa)
	C3ZHH5_BRAFL	Uncharacterized protein. (886 aa)
	C3ZGS6_BRAFL	Uncharacterized protein. (303 aa)
	C3ZG69_BRAFL	Roc domain-containing protein. (982 aa)
	C3ZD52_BRAFL	CABIT domain-containing protein. (614 aa)
	C3ZD51_BRAFL	CABIT domain-containing protein. (386 aa)
	C3ZD49_BRAFL	CABIT domain-containing protein. (637 aa)
	C3ZBM4_BRAFL	Roc domain-containing protein. (871 aa)
	C3ZAU5_BRAFL	Uncharacterized protein. (448 aa)
	C3Z7P8_BRAFL	Uncharacterized protein. (544 aa)
	C3Z7E2_BRAFL	UDENN FLCN/SMCR8-type domain-containing protein. (473 aa)
	C3Z629_BRAFL	Prohibitin. (276 aa)
	C3Z5J9_BRAFL	CC2-LZ domain-containing protein. (694 aa)
	C3Z5H8_BRAFL	CC2-LZ domain-containing protein. (231 aa)
	C3Z3V6_BRAFL	TGF_BETA_2 domain-containing protein. (411 aa)
	C3Z397_BRAFL	Protein kinase domain-containing protein. (1343 aa)
	C3Z1F1_BRAFL	Uncharacterized protein. (468 aa)
	C3YZA6_BRAFL	Uncharacterized protein. (700 aa)
	C3YWB6_BRAFL	Protein kinase domain-containing protein. (128 aa)
	C3YUP9_BRAFL	Protein kinase domain-containing protein. (925 aa)
	C3YUK2_BRAFL	Uncharacterized protein. (214 aa)
	C3YUJ9_BRAFL	Uncharacterized protein. (546 aa)
	C3YTN4_BRAFL	Uncharacterized protein. (349 aa)
	C3YQP4_BRAFL	BZIP domain-containing protein; Belongs to the bZIP family. (321 aa)
	C3YQ30_BRAFL	Peptidyl-prolyl cis-trans isomerase. (151 aa)
	C3YPH5_BRAFL	Protein kinase domain-containing protein. (198 aa)
	C3YKX9_BRAFL	Uncharacterized protein. (564 aa)
	C3YGW8_BRAFL	Uncharacterized protein. (340 aa)
	C3YEW7_BRAFL	Uncharacterized protein. (460 aa)
	C3YDQ8_BRAFL	Mothers against decapentaplegic homolog. (559 aa)
	C3Y7F3_BRAFL	Protein kinase domain-containing protein. (702 aa)
	C3Y6U4_BRAFL	Roc domain-containing protein. (997 aa)
	C3Y177_BRAFL	Uncharacterized protein. (286 aa)
	C3XZR9_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	C3ZP52_BRAFL	Rho-GAP domain-containing protein. (484 aa)
	C3XXX7_BRAFL	PID domain-containing protein. (128 aa)
	C3XWE3_BRAFL	Uncharacterized protein. (394 aa)
	C3XW39_BRAFL	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
	C3XVB1_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	C3XU27_BRAFL	Uncharacterized protein. (1078 aa)
	C3XRK4_BRAFL	Uncharacterized protein. (197 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XW39_BRAFL	C3YTN4_BRAFL	C3XW39	C3YTN4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.488
C3XW39_BRAFL	C3YWB6_BRAFL	C3XW39	C3YWB6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein kinase domain-containing protein.	0.559
C3XW39_BRAFL	C3Z3V6_BRAFL	C3XW39	C3Z3V6	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	TGF_BETA_2 domain-containing protein.	0.431
C3XZR9_BRAFL	C3ZPE4_BRAFL	C3XZR9	C3ZPE4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Protein kinase domain-containing protein.	0.533
C3Y7F3_BRAFL	C3ZPE4_BRAFL	C3Y7F3	C3ZPE4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.435
C3YDQ8_BRAFL	C3YQP4_BRAFL	C3YDQ8	C3YQP4	Mothers against decapentaplegic homolog.	BZIP domain-containing protein; Belongs to the bZIP family.	0.735
C3YDQ8_BRAFL	C3Z3V6_BRAFL	C3YDQ8	C3Z3V6	Mothers against decapentaplegic homolog.	TGF_BETA_2 domain-containing protein.	0.787
C3YGW8_BRAFL	C3ZPE4_BRAFL	C3YGW8	C3ZPE4	Uncharacterized protein.	Protein kinase domain-containing protein.	0.486
C3YQP4_BRAFL	C3YDQ8_BRAFL	C3YQP4	C3YDQ8	BZIP domain-containing protein; Belongs to the bZIP family.	Mothers against decapentaplegic homolog.	0.735
C3YQP4_BRAFL	C3YTN4_BRAFL	C3YQP4	C3YTN4	BZIP domain-containing protein; Belongs to the bZIP family.	Uncharacterized protein.	0.429
C3YQP4_BRAFL	C3ZPE4_BRAFL	C3YQP4	C3ZPE4	BZIP domain-containing protein; Belongs to the bZIP family.	Protein kinase domain-containing protein.	0.600
C3YTN4_BRAFL	C3XW39_BRAFL	C3YTN4	C3XW39	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.488
C3YTN4_BRAFL	C3YQP4_BRAFL	C3YTN4	C3YQP4	Uncharacterized protein.	BZIP domain-containing protein; Belongs to the bZIP family.	0.429
C3YUJ9_BRAFL	C3ZTT7_BRAFL	C3YUJ9	C3ZTT7	Uncharacterized protein.	FAD-binding FR-type domain-containing protein.	0.545
C3YUP9_BRAFL	C3ZPE4_BRAFL	C3YUP9	C3ZPE4	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.530
C3YWB6_BRAFL	C3XW39_BRAFL	C3YWB6	C3XW39	Protein kinase domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.559
C3Z3V6_BRAFL	C3XW39_BRAFL	C3Z3V6	C3XW39	TGF_BETA_2 domain-containing protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.431
C3Z3V6_BRAFL	C3YDQ8_BRAFL	C3Z3V6	C3YDQ8	TGF_BETA_2 domain-containing protein.	Mothers against decapentaplegic homolog.	0.787
C3ZPE4_BRAFL	C3XZR9_BRAFL	C3ZPE4	C3XZR9	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.533
C3ZPE4_BRAFL	C3Y7F3_BRAFL	C3ZPE4	C3Y7F3	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.435