(30 nodes) Clathrin-dependent endocytosis network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3Z1G4_BRAFL	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (950 aa)
	C3YZV8_BRAFL	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
	C3YXU9_BRAFL	ENTH domain-containing protein. (623 aa)
	C3YXP3_BRAFL	Uncharacterized protein. (694 aa)
	C3YTZ4_BRAFL	Uncharacterized protein. (541 aa)
	C3YR04_BRAFL	Uncharacterized protein. (565 aa)
	C3YN10_BRAFL	Uncharacterized protein. (988 aa)
	C3YN09_BRAFL	Uncharacterized protein. (521 aa)
	C3YN06_BRAFL	Uncharacterized protein. (492 aa)
	C3YKC9_BRAFL	Uncharacterized protein. (1206 aa)
	C3YK94_BRAFL	Uncharacterized protein. (556 aa)
	C3YIJ6_BRAFL	FCH domain-containing protein. (457 aa)
	C3YIJ5_BRAFL	MHD domain-containing protein. (672 aa)
	C3Y4I4_BRAFL	Uncharacterized protein. (333 aa)
	C3XZS0_BRAFL	Uncharacterized protein. (957 aa)
	C3XQ78_BRAFL	Uncharacterized protein. (483 aa)
	C3XQ77_BRAFL	Uncharacterized protein. (527 aa)
	C3XQ63_BRAFL	Uncharacterized protein. (1056 aa)
	C3XQ61_BRAFL	Uncharacterized protein. (533 aa)
	C3XQ62_BRAFL	Uncharacterized protein. (979 aa)
	C3ZVY2_BRAFL	Uncharacterized protein. (919 aa)
	C3ZVY1_BRAFL	Protein kinase domain-containing protein. (149 aa)
	C3ZLV4_BRAFL	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (351 aa)
	C3ZLK1_BRAFL	Uncharacterized protein. (160 aa)
	C3ZLK0_BRAFL	Uncharacterized protein. (1250 aa)
	C3ZIG2_BRAFL	Uncharacterized protein. (551 aa)
	C3ZCW3_BRAFL	Uncharacterized protein. (574 aa)
	C3Z9A8_BRAFL	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1533 aa)
	C3XPL3_BRAFL	Uncharacterized protein. (433 aa)
	C3Z3J8_BRAFL	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3Y4I4_BRAFL	C3YZV8_BRAFL	C3Y4I4	C3YZV8	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.671
C3Y4I4_BRAFL	C3Z3J8_BRAFL	C3Y4I4	C3Z3J8	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.571
C3Y4I4_BRAFL	C3Z9A8_BRAFL	C3Y4I4	C3Z9A8	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.669
C3Y4I4_BRAFL	C3ZLK0_BRAFL	C3Y4I4	C3ZLK0	Uncharacterized protein.	Uncharacterized protein.	0.969
C3Y4I4_BRAFL	C3ZLK1_BRAFL	C3Y4I4	C3ZLK1	Uncharacterized protein.	Uncharacterized protein.	0.969
C3Y4I4_BRAFL	C3ZLV4_BRAFL	C3Y4I4	C3ZLV4	Uncharacterized protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.681
C3Y4I4_BRAFL	C3ZVY1_BRAFL	C3Y4I4	C3ZVY1	Uncharacterized protein.	Protein kinase domain-containing protein.	0.993
C3Y4I4_BRAFL	C3ZVY2_BRAFL	C3Y4I4	C3ZVY2	Uncharacterized protein.	Uncharacterized protein.	0.993
C3YIJ5_BRAFL	C3YIJ6_BRAFL	C3YIJ5	C3YIJ6	MHD domain-containing protein.	FCH domain-containing protein.	0.848
C3YIJ5_BRAFL	C3YXU9_BRAFL	C3YIJ5	C3YXU9	MHD domain-containing protein.	ENTH domain-containing protein.	0.631
C3YIJ5_BRAFL	C3YZV8_BRAFL	C3YIJ5	C3YZV8	MHD domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.715
C3YIJ5_BRAFL	C3Z1G4_BRAFL	C3YIJ5	C3Z1G4	MHD domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.696
C3YIJ5_BRAFL	C3Z3J8_BRAFL	C3YIJ5	C3Z3J8	MHD domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.804
C3YIJ5_BRAFL	C3Z9A8_BRAFL	C3YIJ5	C3Z9A8	MHD domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.720
C3YIJ5_BRAFL	C3ZLK0_BRAFL	C3YIJ5	C3ZLK0	MHD domain-containing protein.	Uncharacterized protein.	0.983
C3YIJ5_BRAFL	C3ZLK1_BRAFL	C3YIJ5	C3ZLK1	MHD domain-containing protein.	Uncharacterized protein.	0.983
C3YIJ5_BRAFL	C3ZLV4_BRAFL	C3YIJ5	C3ZLV4	MHD domain-containing protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.809
C3YIJ5_BRAFL	C3ZVY1_BRAFL	C3YIJ5	C3ZVY1	MHD domain-containing protein.	Protein kinase domain-containing protein.	0.615
C3YIJ5_BRAFL	C3ZVY2_BRAFL	C3YIJ5	C3ZVY2	MHD domain-containing protein.	Uncharacterized protein.	0.615
C3YIJ6_BRAFL	C3YIJ5_BRAFL	C3YIJ6	C3YIJ5	FCH domain-containing protein.	MHD domain-containing protein.	0.848