(39 nodes) Positive regulation of canonical Wnt signaling pathway network (Branchiostoma floridae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZXM0_BRAFL	Uncharacterized protein. (169 aa)
	C3ZKQ3_BRAFL	USP domain-containing protein; Belongs to the peptidase C19 family. (3746 aa)
	C3ZJ85_BRAFL	Uncharacterized protein. (464 aa)
	C3ZEX7_BRAFL	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (208 aa)
	C3ZEX6_BRAFL	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (361 aa)
	C3ZEP1_BRAFL	Uncharacterized protein. (499 aa)
	C3ZDW6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (412 aa)
	C3ZDW4_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (288 aa)
	C3ZDW2_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (374 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZAI1_BRAFL	Uncharacterized protein. (181 aa)
	C3ZAI0_BRAFL	Uncharacterized protein. (206 aa)
	C3ZAH8_BRAFL	Uncharacterized protein. (2208 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3Z3B0_BRAFL	Uncharacterized protein. (866 aa)
	C3YWQ0_BRAFL	Protein kinase domain-containing protein. (511 aa)
	C3YW41_BRAFL	DUF4203 domain-containing protein. (264 aa)
	C3YRU2_BRAFL	Protein kinase domain-containing protein. (168 aa)
	C3YQ30_BRAFL	Peptidyl-prolyl cis-trans isomerase. (151 aa)
	C3YPH5_BRAFL	Protein kinase domain-containing protein. (198 aa)
	C3YN37_BRAFL	Uncharacterized protein. (1290 aa)
	C3YJH1_BRAFL	Uncharacterized protein. (354 aa)
	C3YE67_BRAFL	Uncharacterized protein; Belongs to the tumor necrosis factor family. (180 aa)
	C3YCH7_BRAFL	RING-type domain-containing protein. (350 aa)
	C3YCH6_BRAFL	Uncharacterized protein. (152 aa)
	C3Y7M2_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1318 aa)
	C3Y6U5_BRAFL	Uncharacterized protein. (360 aa)
	C3Y203_BRAFL	Casein kinase 1 protein, gamma; Belongs to the protein kinase superfamily. (408 aa)
	C3Y1S7_BRAFL	Roc domain-containing protein. (873 aa)
	C3Y1L1_BRAFL	Uncharacterized protein. (205 aa)
	C3XZ56_BRAFL	PPM-type phosphatase domain-containing protein. (382 aa)
	C3XW39_BRAFL	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
	C3XVS4_BRAFL	WD_REPEATS_REGION domain-containing protein. (187 aa)
	C3XVS3_BRAFL	WD_REPEATS_REGION domain-containing protein. (200 aa)
	C3XVR3_BRAFL	WD_REPEATS_REGION domain-containing protein. (187 aa)
	C3XVR2_BRAFL	WD_REPEATS_REGION domain-containing protein. (353 aa)
	C3ZQT3_BRAFL	Uncharacterized protein. (228 aa)
	C3ZS25_BRAFL	Uncharacterized protein. (2721 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XVR2_BRAFL	C3XVR3_BRAFL	C3XVR2	C3XVR3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR2_BRAFL	C3XVS4_BRAFL	C3XVR2	C3XVS4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR3_BRAFL	C3XVR2_BRAFL	C3XVR3	C3XVR2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVR3_BRAFL	C3XVS3_BRAFL	C3XVR3	C3XVS3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS3_BRAFL	C3XVR3_BRAFL	C3XVS3	C3XVR3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS3_BRAFL	C3XVS4_BRAFL	C3XVS3	C3XVS4	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.916
C3XVS4_BRAFL	C3XVR2_BRAFL	C3XVS4	C3XVR2	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.915
C3XVS4_BRAFL	C3XVS3_BRAFL	C3XVS4	C3XVS3	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.916
C3Y1L1_BRAFL	C3ZKQ3_BRAFL	C3Y1L1	C3ZKQ3	Uncharacterized protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.574
C3Z851_BRAFL	C3ZB87_BRAFL	C3Z851	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z851_BRAFL	C3ZB88_BRAFL	C3Z851	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3Z851_BRAFL	C3ZB87	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3ZB88_BRAFL	C3ZB87	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZB88_BRAFL	C3Z851_BRAFL	C3ZB88	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB88_BRAFL	C3ZB87_BRAFL	C3ZB88	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZKQ3_BRAFL	C3Y1L1_BRAFL	C3ZKQ3	C3Y1L1	USP domain-containing protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.574
C3ZKQ3_BRAFL	C3ZS25_BRAFL	C3ZKQ3	C3ZS25	USP domain-containing protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.645
C3ZS25_BRAFL	C3ZKQ3_BRAFL	C3ZS25	C3ZKQ3	Uncharacterized protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.645