(88 nodes) Apoptotic signaling pathway network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZXH5_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (439 aa)
	C3ZY21_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (246 aa)
	C3ZY28_BRAFL	CARD domain-containing protein. (105 aa)
	C3ZZM6_BRAFL	Uncharacterized protein. (197 aa)
	C3Z749_BRAFL	Uncharacterized protein. (1464 aa)
	C3Z6D7_BRAFL	Uncharacterized protein. (1235 aa)
	C3Z4T1_BRAFL	Uncharacterized protein. (142 aa)
	C3Z4P8_BRAFL	Uncharacterized protein. (195 aa)
	C3Z3M8_BRAFL	Uncharacterized protein. (225 aa)
	C3Z2N3_BRAFL	Uncharacterized protein. (621 aa)
	C3YZW2_BRAFL	Uncharacterized protein. (485 aa)
	C3YZV6_BRAFL	Uncharacterized protein. (1238 aa)
	C3YZC7_BRAFL	Uncharacterized protein. (164 aa)
	C3YZC3_BRAFL	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (307 aa)
	C3YZ38_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (809 aa)
	C3YYL2_BRAFL	Uncharacterized protein. (106 aa)
	C3YXH3_BRAFL	Uncharacterized protein. (416 aa)
	C3YWJ7_BRAFL	Uncharacterized protein. (436 aa)
	C3YW39_BRAFL	Uncharacterized protein. (2614 aa)
	C3YW28_BRAFL	TGF_BETA_2 domain-containing protein. (400 aa)
	C3YW20_BRAFL	TGF_BETA_2 domain-containing protein. (308 aa)
	C3YTN8_BRAFL	RING-type domain-containing protein. (200 aa)
	C3YTC0_BRAFL	TM2 domain-containing protein. (152 aa)
	C3YPG2_BRAFL	Uncharacterized protein. (188 aa)
	C3YMN6_BRAFL	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1278 aa)
	C3YMM0_BRAFL	Uncharacterized protein. (381 aa)
	C3YM60_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (540 aa)
	C3YKX2_BRAFL	Deacetylase sirtuin-type domain-containing protein. (312 aa)
	C3YJ97_BRAFL	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (615 aa)
	C3YJ81_BRAFL	Uncharacterized protein. (645 aa)
	C3YH73_BRAFL	FAT domain-containing protein. (2357 aa)
	C3YH71_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (553 aa)
	C3YF65_BRAFL	Uncharacterized protein. (488 aa)
	C3YF64_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4388 aa)
	C3YF62_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (311 aa)
	C3YEQ1_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (476 aa)
	C3YAZ4_BRAFL	CARD domain-containing protein. (324 aa)
	C3YAV7_BRAFL	VPS10 domain-containing protein. (246 aa)
	C3Y9T6_BRAFL	TGF_BETA_2 domain-containing protein. (109 aa)
	C3Y9J6_BRAFL	HMG box domain-containing protein. (334 aa)
	C3Y9A3_BRAFL	ATPase_AAA_core domain-containing protein. (2025 aa)
	C3Y8G6_BRAFL	Death domain-containing protein. (1064 aa)
	C3Y7M2_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1318 aa)
	C3Y726_BRAFL	Uncharacterized protein. (215 aa)
	C3Y543_BRAFL	Uncharacterized protein. (420 aa)
	C3Y458_BRAFL	DNA_mis_repair domain-containing protein. (717 aa)
	C3Y396_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (242 aa)
	C3Y272_BRAFL	Uncharacterized protein. (243 aa)
	C3Y1Z6_BRAFL	Uncharacterized protein. (144 aa)
	C3Y0G1_BRAFL	Glycogen synthase kinase-3 beta; Belongs to the protein kinase superfamily. (420 aa)
	C3Y062_BRAFL	Uncharacterized protein. (566 aa)
	C3XXK4_BRAFL	Uncharacterized protein. (414 aa)
	C3XX77_BRAFL	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (248 aa)
	C3XUC4_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (399 aa)
	C3XTK2_BRAFL	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (905 aa)
	C3XRP1_BRAFL	Uncharacterized protein. (1157 aa)
	C3XQU2_BRAFL	SKIP_SNW domain-containing protein. (543 aa)
	C3XQC7_BRAFL	POLXc domain-containing protein. (186 aa)
	C3XPU2_BRAFL	Uncharacterized protein. (649 aa)
	C3XPS9_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (309 aa)
	C3ZQ72_BRAFL	Uncharacterized protein. (173 aa)
	C3ZQQ4_BRAFL	Uncharacterized protein. (197 aa)
	C3ZQU2_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (739 aa)
	C3ZV28_BRAFL	Uncharacterized protein. (383 aa)
	C3ZV77_BRAFL	Ras-GAP domain-containing protein. (1311 aa)
	C3ZV81_BRAFL	CRAL-TRIO domain-containing protein. (1389 aa)
	C3ZVC0_BRAFL	Uncharacterized protein. (143 aa)
	C3ZVC1_BRAFL	Uncharacterized protein. (271 aa)
	C3ZXH2_BRAFL	Uncharacterized protein; Belongs to the peptidase C14A family. (340 aa)
	C3ZXZ8_BRAFL	Death domain-containing protein. (298 aa)
	C3ZHX7_BRAFL	Poly [ADP-ribose] polymerase. (486 aa)
	C3ZIW3_BRAFL	P53 domain-containing protein. (82 aa)
	C3ZPA3_BRAFL	Daxx domain-containing protein. (323 aa)
	C3ZPB8_BRAFL	BTB domain-containing protein. (124 aa)
	C3ZPB9_BRAFL	Uncharacterized protein. (274 aa)
	C3ZHE1_BRAFL	C2H2-type domain-containing protein. (447 aa)
	C3ZFB2_BRAFL	Uncharacterized protein. (164 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZAV0_BRAFL	Uncharacterized protein. (956 aa)
	C3ZAU6_BRAFL	Uncharacterized protein. (174 aa)
	C3ZAH9_BRAFL	Uncharacterized protein. (599 aa)
	C3ZAE2_BRAFL	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (707 aa)
	C3ZAA2_BRAFL	Bis(5'-adenosyl)-triphosphatase. (157 aa)
	C3Z9G3_BRAFL	Ubiquitin-like domain-containing protein. (1268 aa)
	C3Z946_BRAFL	Uncharacterized protein. (310 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3Z7E2_BRAFL	UDENN FLCN/SMCR8-type domain-containing protein. (473 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPS9_BRAFL	C3YJ81_BRAFL	C3XPS9	C3YJ81	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.541
C3XPS9_BRAFL	C3YPG2_BRAFL	C3XPS9	C3YPG2	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.504
C3XPS9_BRAFL	C3YZV6_BRAFL	C3XPS9	C3YZV6	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.585
C3XPS9_BRAFL	C3ZQQ4_BRAFL	C3XPS9	C3ZQQ4	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.504
C3XPU2_BRAFL	C3YH71_BRAFL	C3XPU2	C3YH71	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.609
C3XPU2_BRAFL	C3YH73_BRAFL	C3XPU2	C3YH73	Uncharacterized protein.	FAT domain-containing protein.	0.609
C3XPU2_BRAFL	C3YZV6_BRAFL	C3XPU2	C3YZV6	Uncharacterized protein.	Uncharacterized protein.	0.416
C3XPU2_BRAFL	C3ZV28_BRAFL	C3XPU2	C3ZV28	Uncharacterized protein.	Uncharacterized protein.	0.654
C3XQC7_BRAFL	C3Y7M2_BRAFL	C3XQC7	C3Y7M2	POLXc domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.732
C3XQC7_BRAFL	C3YF62_BRAFL	C3XQC7	C3YF62	POLXc domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.406
C3XQC7_BRAFL	C3YF64_BRAFL	C3XQC7	C3YF64	POLXc domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.406
C3XQC7_BRAFL	C3Z6D7_BRAFL	C3XQC7	C3Z6D7	POLXc domain-containing protein.	Uncharacterized protein.	0.435
C3XQC7_BRAFL	C3ZHX7_BRAFL	C3XQC7	C3ZHX7	POLXc domain-containing protein.	Poly [ADP-ribose] polymerase.	0.868
C3XTK2_BRAFL	C3Y458_BRAFL	C3XTK2	C3Y458	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	DNA_mis_repair domain-containing protein.	0.997
C3XTK2_BRAFL	C3YH71_BRAFL	C3XTK2	C3YH71	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.576
C3XTK2_BRAFL	C3YH73_BRAFL	C3XTK2	C3YH73	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	FAT domain-containing protein.	0.576
C3XTK2_BRAFL	C3YMN6_BRAFL	C3XTK2	C3YMN6	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.999
C3XTK2_BRAFL	C3YW39_BRAFL	C3XTK2	C3YW39	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	Uncharacterized protein.	0.724
C3XTK2_BRAFL	C3ZV28_BRAFL	C3XTK2	C3ZV28	DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).	Uncharacterized protein.	0.648
C3XUC4_BRAFL	C3YEQ1_BRAFL	C3XUC4	C3YEQ1	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.587