(67 nodes) Negative regulation of protein localization network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZWB1_BRAFL	Uncharacterized protein. (465 aa)
	C3Y4F4_BRAFL	Uncharacterized protein. (676 aa)
	C3Y604_BRAFL	Uncharacterized protein. (448 aa)
	C3Y6U4_BRAFL	Roc domain-containing protein. (997 aa)
	C3Y771_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein. (388 aa)
	C3Y960_BRAFL	Rhomboid domain-containing protein. (1084 aa)
	C3YAF2_BRAFL	OTU domain-containing protein. (315 aa)
	C3YBI5_BRAFL	3-hydroxy-3-methylglutaryl coenzyme A reductase. (876 aa)
	C3YC59_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (187 aa)
	C3YC60_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (187 aa)
	C3YC61_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (188 aa)
	C3YCM0_BRAFL	F-box domain-containing protein. (317 aa)
	C3YCU3_BRAFL	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (302 aa)
	C3YJ16_BRAFL	Rhomboid domain-containing protein. (531 aa)
	C3YJ17_BRAFL	Uncharacterized protein. (735 aa)
	C3YLQ4_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (316 aa)
	C3YMM0_BRAFL	Uncharacterized protein. (381 aa)
	C3YN59_BRAFL	Uncharacterized protein. (303 aa)
	C3YUF0_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (219 aa)
	C3YYG7_BRAFL	Uncharacterized protein. (449 aa)
	C3Z1N9_BRAFL	N_BRCA1_IG domain-containing protein. (394 aa)
	C3Z2I5_BRAFL	Uncharacterized protein. (430 aa)
	C3Z3J5_BRAFL	Uncharacterized protein. (192 aa)
	C3Z4B6_BRAFL	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (257 aa)
	C3Z502_BRAFL	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (434 aa)
	C3Z6L3_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (283 aa)
	C3Z6L4_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein. (104 aa)
	C3Z7E2_BRAFL	UDENN FLCN/SMCR8-type domain-containing protein. (473 aa)
	C3Z8L1_BRAFL	Uncharacterized protein. (224 aa)
	C3Z989_BRAFL	UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
	C3Z9A8_BRAFL	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1533 aa)
	C3Z9K6_BRAFL	PRKCSH domain-containing protein. (271 aa)
	C3ZAH8_BRAFL	Uncharacterized protein. (2208 aa)
	C3ZAI0_BRAFL	Uncharacterized protein. (206 aa)
	C3ZAI1_BRAFL	Uncharacterized protein. (181 aa)
	C3ZBM4_BRAFL	Roc domain-containing protein. (871 aa)
	C3ZBT9_BRAFL	Uncharacterized protein. (225 aa)
	C3ZBW5_BRAFL	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1731 aa)
	C3ZEB9_BRAFL	PID domain-containing protein. (70 aa)
	C3ZF68_BRAFL	Lipocln_cytosolic_FA-bd_dom domain-containing protein. (190 aa)
	C3ZG69_BRAFL	Roc domain-containing protein. (982 aa)
	C3ZHY9_BRAFL	Uncharacterized protein. (537 aa)
	Hsd11b1F	PDZ domain-containing protein. (199 aa)
	C3ZKV0_BRAFL	IPPc domain-containing protein. (524 aa)
	C3ZM59_BRAFL	Uncharacterized protein. (279 aa)
	C3ZN00_BRAFL	Protein kinase domain-containing protein. (491 aa)
	C3ZNT3_BRAFL	PDZ domain-containing protein. (660 aa)
	C3ZR37_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (306 aa)
	C3ZRP0_BRAFL	Roc domain-containing protein. (895 aa)
	C3ZS01_BRAFL	RAS oncogene protein. (237 aa)
	C3ZV77_BRAFL	Ras-GAP domain-containing protein. (1311 aa)
	C3ZV81_BRAFL	CRAL-TRIO domain-containing protein. (1389 aa)
	C3Y381_BRAFL	Elp3 domain-containing protein. (343 aa)
	C3ZWB2_BRAFL	Uncharacterized protein. (588 aa)
	C3ZZD3_BRAFL	Uncharacterized protein. (189 aa)
	C4A017_BRAFL	Uncharacterized protein. (205 aa)
	rab-GDI	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (446 aa)
	C3XUQ0_BRAFL	PX domain-containing protein. (164 aa)
	C3XVY8_BRAFL	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (414 aa)
	C3XWF7_BRAFL	Uncharacterized protein. (607 aa)
	C3XXX7_BRAFL	PID domain-containing protein. (128 aa)
	C3XXZ2_BRAFL	PDZ domain-containing protein. (97 aa)
	C3XY41_BRAFL	Ubiquitin-like domain-containing protein. (394 aa)
	C3XY56_BRAFL	Uncharacterized protein. (155 aa)
	C3Y177_BRAFL	Uncharacterized protein. (286 aa)
	C3Y212_BRAFL	Deacetylase sirtuin-type domain-containing protein. (414 aa)
	C3Y288_BRAFL	Uncharacterized protein. (366 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XVY8_BRAFL	C3Z989_BRAFL	C3XVY8	C3Z989	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.495
C3XXX7_BRAFL	C3Z9A8_BRAFL	C3XXX7	C3Z9A8	PID domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.724
C3Y212_BRAFL	C3YCU3_BRAFL	C3Y212	C3YCU3	Deacetylase sirtuin-type domain-containing protein.	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	0.579
C3Y288_BRAFL	C3YAF2_BRAFL	C3Y288	C3YAF2	Uncharacterized protein.	OTU domain-containing protein.	0.978
C3Y288_BRAFL	C3Z4B6_BRAFL	C3Y288	C3Z4B6	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.650
C3Y4F4_BRAFL	C3Z989_BRAFL	C3Y4F4	C3Z989	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.471
C3YAF2_BRAFL	C3Y288_BRAFL	C3YAF2	C3Y288	OTU domain-containing protein.	Uncharacterized protein.	0.978
C3YCU3_BRAFL	C3Y212_BRAFL	C3YCU3	C3Y212	NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.	Deacetylase sirtuin-type domain-containing protein.	0.579
C3YMM0_BRAFL	C3Z9A8_BRAFL	C3YMM0	C3Z9A8	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.444
C3YMM0_BRAFL	C3ZWB1_BRAFL	C3YMM0	C3ZWB1	Uncharacterized protein.	Uncharacterized protein.	0.615
C3YMM0_BRAFL	C3ZWB2_BRAFL	C3YMM0	C3ZWB2	Uncharacterized protein.	Uncharacterized protein.	0.615
C3Z2I5_BRAFL	C3Z4B6_BRAFL	C3Z2I5	C3Z4B6	Uncharacterized protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.970
C3Z2I5_BRAFL	C3Z989_BRAFL	C3Z2I5	C3Z989	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.514
C3Z4B6_BRAFL	C3Y288_BRAFL	C3Z4B6	C3Y288	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.650
C3Z4B6_BRAFL	C3Z2I5_BRAFL	C3Z4B6	C3Z2I5	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.970
C3Z4B6_BRAFL	C3Z989_BRAFL	C3Z4B6	C3Z989	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.556
C3Z4B6_BRAFL	C3Z9K6_BRAFL	C3Z4B6	C3Z9K6	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	PRKCSH domain-containing protein.	0.970
C3Z502_BRAFL	C3Z989_BRAFL	C3Z502	C3Z989	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.495
C3Z989_BRAFL	C3XVY8_BRAFL	C3Z989	C3XVY8	UBIQUITIN_CONJUGAT_2 domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.495
C3Z989_BRAFL	C3Y4F4_BRAFL	C3Z989	C3Y4F4	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Uncharacterized protein.	0.471