(59 nodes) RNA polymerase II, holoenzyme network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZDV6_BRAFL	Uncharacterized protein. (559 aa)
	C4A0W1_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (326 aa)
	C3ZTF7_BRAFL	Uncharacterized protein. (567 aa)
	C3ZTF5_BRAFL	WD_REPEATS_REGION domain-containing protein. (319 aa)
	C3ZT09_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (326 aa)
	C3ZSP8_BRAFL	Uncharacterized protein. (592 aa)
	C3ZQZ0_BRAFL	Uncharacterized protein. (172 aa)
	C3ZQG2_BRAFL	Plus3 domain-containing protein. (605 aa)
	C3ZQF0_BRAFL	Uncharacterized protein. (210 aa)
	C3ZLN6_BRAFL	Uncharacterized protein. (162 aa)
	C3ZLA4_BRAFL	Uncharacterized protein. (284 aa)
	C3ZG24_BRAFL	Uncharacterized protein. (536 aa)
	C3ZES3_BRAFL	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1934 aa)
	C3ZDV4_BRAFL	WD_REPEATS_REGION domain-containing protein. (444 aa)
	C3ZC47_BRAFL	BTP domain-containing protein. (286 aa)
	C3ZB99_BRAFL	CID domain-containing protein. (323 aa)
	C3ZAC6_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (340 aa)
	C3Z9P4_BRAFL	Uncharacterized protein. (525 aa)
	C3Z918_BRAFL	RPOLD domain-containing protein. (275 aa)
	C3Z898_BRAFL	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
	C3Z5Q6_BRAFL	Uncharacterized protein. (71 aa)
	C3Z4E3_BRAFL	WD_REPEATS_REGION domain-containing protein. (274 aa)
	C3Z2E0_BRAFL	HTH TFE/IIEalpha-type domain-containing protein. (429 aa)
	C3YZS6_BRAFL	Uncharacterized protein. (425 aa)
	C3YZS4_BRAFL	Uncharacterized protein. (122 aa)
	C3YY41_BRAFL	RNA_pol_L_2 domain-containing protein. (117 aa)
	C3YXI9_BRAFL	Peptidase_M1 domain-containing protein. (995 aa)
	C3YX15_BRAFL	Peptidase_M1 domain-containing protein. (1059 aa)
	C3YW09_BRAFL	TAFII28 domain-containing protein. (106 aa)
	C3YVD4_BRAFL	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (298 aa)
	C3YTQ8_BRAFL	RTR1-type domain-containing protein. (653 aa)
	C3YTK8_BRAFL	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (457 aa)
	C3YQX8_BRAFL	CID domain-containing protein. (313 aa)
	C3YQI6_BRAFL	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (534 aa)
	C3YN18_BRAFL	General transcription factor IIH subunit. (396 aa)
	C3YMZ1_BRAFL	RING-type domain-containing protein. (361 aa)
	C3YLI3_BRAFL	PHD-type domain-containing protein. (1052 aa)
	C3YK92_BRAFL	Uncharacterized protein. (100 aa)
	C3YH75_BRAFL	Uncharacterized protein. (129 aa)
	C3YEN1_BRAFL	TAFH domain-containing protein. (590 aa)
	C3YEN0_BRAFL	Uncharacterized protein. (721 aa)
	C3YEK2_BRAFL	WD_REPEATS_REGION domain-containing protein. (1491 aa)
	C3YD69_BRAFL	Uncharacterized protein. (573 aa)
	C3YBY7_BRAFL	Uncharacterized protein. (798 aa)
	C3YBM8_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (218 aa)
	C3YBM6_BRAFL	Uncharacterized protein. (138 aa)
	C3YA64_BRAFL	Uncharacterized protein. (352 aa)
	C3Y693_BRAFL	Uncharacterized protein. (551 aa)
	C3Y645_BRAFL	Uncharacterized protein. (68 aa)
	C3Y5U9_BRAFL	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1104 aa)
	C3Y529_BRAFL	TPR_REGION domain-containing protein. (1183 aa)
	C3Y3A3_BRAFL	Uncharacterized protein. (2008 aa)
	C3Y0I0_BRAFL	Uncharacterized protein. (311 aa)
	C3XU46_BRAFL	TAFH domain-containing protein. (78 aa)
	C3XU45_BRAFL	TAF4 domain-containing protein. (58 aa)
	C3XU44_BRAFL	TAF4 domain-containing protein. (195 aa)
	C3XRA2_BRAFL	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
	C3XR97_BRAFL	Uncharacterized protein. (198 aa)
	C3XPX8_BRAFL	RPOL4c domain-containing protein. (142 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPX8_BRAFL	C3XR97_BRAFL	C3XPX8	C3XR97	RPOL4c domain-containing protein.	Uncharacterized protein.	0.858
C3XPX8_BRAFL	C3XRA2_BRAFL	C3XPX8	C3XRA2	RPOL4c domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
C3XPX8_BRAFL	C3XU44_BRAFL	C3XPX8	C3XU44	RPOL4c domain-containing protein.	TAF4 domain-containing protein.	0.582
C3XPX8_BRAFL	C3XU45_BRAFL	C3XPX8	C3XU45	RPOL4c domain-containing protein.	TAF4 domain-containing protein.	0.582
C3XPX8_BRAFL	C3XU46_BRAFL	C3XPX8	C3XU46	RPOL4c domain-containing protein.	TAFH domain-containing protein.	0.582
C3XPX8_BRAFL	C3Y0I0_BRAFL	C3XPX8	C3Y0I0	RPOL4c domain-containing protein.	Uncharacterized protein.	0.961
C3XPX8_BRAFL	C3Y3A3_BRAFL	C3XPX8	C3Y3A3	RPOL4c domain-containing protein.	Uncharacterized protein.	0.797
C3XPX8_BRAFL	C3Y529_BRAFL	C3XPX8	C3Y529	RPOL4c domain-containing protein.	TPR_REGION domain-containing protein.	0.890
C3XPX8_BRAFL	C3Y5U9_BRAFL	C3XPX8	C3Y5U9	RPOL4c domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
C3XPX8_BRAFL	C3Y645_BRAFL	C3XPX8	C3Y645	RPOL4c domain-containing protein.	Uncharacterized protein.	0.999
C3XPX8_BRAFL	C3Y693_BRAFL	C3XPX8	C3Y693	RPOL4c domain-containing protein.	Uncharacterized protein.	0.967
C3XPX8_BRAFL	C3YA64_BRAFL	C3XPX8	C3YA64	RPOL4c domain-containing protein.	Uncharacterized protein.	0.887
C3XPX8_BRAFL	C3YBM6_BRAFL	C3XPX8	C3YBM6	RPOL4c domain-containing protein.	Uncharacterized protein.	0.740
C3XPX8_BRAFL	C3YBM8_BRAFL	C3XPX8	C3YBM8	RPOL4c domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.740
C3XPX8_BRAFL	C3YBY7_BRAFL	C3XPX8	C3YBY7	RPOL4c domain-containing protein.	Uncharacterized protein.	0.971
C3XPX8_BRAFL	C3YD69_BRAFL	C3XPX8	C3YD69	RPOL4c domain-containing protein.	Uncharacterized protein.	0.965
C3XPX8_BRAFL	C3YEK2_BRAFL	C3XPX8	C3YEK2	RPOL4c domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.621
C3XPX8_BRAFL	C3YEN0_BRAFL	C3XPX8	C3YEN0	RPOL4c domain-containing protein.	Uncharacterized protein.	0.582
C3XPX8_BRAFL	C3YEN1_BRAFL	C3XPX8	C3YEN1	RPOL4c domain-containing protein.	TAFH domain-containing protein.	0.582
C3XPX8_BRAFL	C3YH75_BRAFL	C3XPX8	C3YH75	RPOL4c domain-containing protein.	Uncharacterized protein.	0.999