(10 nodes) HOPS complex network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZET7_BRAFL	DSBA domain-containing protein. (1906 aa)
	C3YKV1_BRAFL	RING-type domain-containing protein. (894 aa)
	C3ZYQ6_BRAFL	RING-type domain-containing protein. (316 aa)
	C3ZUU8_BRAFL	RING-type domain-containing protein. (212 aa)
	C3ZIW0_BRAFL	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (795 aa)
	C3YG76_BRAFL	WD_REPEATS_REGION domain-containing protein. (396 aa)
	C3Y4D1_BRAFL	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (804 aa)
	C3XXM3_BRAFL	Pep3_Vps18 domain-containing protein. (986 aa)
	C3XTS9_BRAFL	WD_REPEATS_REGION domain-containing protein. (244 aa)
	C3YXH4_BRAFL	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (761 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XXM3_BRAFL	C3Y4D1_BRAFL	C3XXM3	C3Y4D1	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.998
C3XXM3_BRAFL	C3YKV1_BRAFL	C3XXM3	C3YKV1	Pep3_Vps18 domain-containing protein.	RING-type domain-containing protein.	0.998
C3XXM3_BRAFL	C3YXH4_BRAFL	C3XXM3	C3YXH4	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.977
C3XXM3_BRAFL	C3ZIW0_BRAFL	C3XXM3	C3ZIW0	Pep3_Vps18 domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.977
C3XXM3_BRAFL	C3ZUU8_BRAFL	C3XXM3	C3ZUU8	Pep3_Vps18 domain-containing protein.	RING-type domain-containing protein.	0.965
C3XXM3_BRAFL	C3ZYQ6_BRAFL	C3XXM3	C3ZYQ6	Pep3_Vps18 domain-containing protein.	RING-type domain-containing protein.	0.965
C3Y4D1_BRAFL	C3XXM3_BRAFL	C3Y4D1	C3XXM3	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Pep3_Vps18 domain-containing protein.	0.998
C3Y4D1_BRAFL	C3YKV1_BRAFL	C3Y4D1	C3YKV1	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	RING-type domain-containing protein.	0.998
C3Y4D1_BRAFL	C3YXH4_BRAFL	C3Y4D1	C3YXH4	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.975
C3Y4D1_BRAFL	C3ZIW0_BRAFL	C3Y4D1	C3ZIW0	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.975
C3Y4D1_BRAFL	C3ZUU8_BRAFL	C3Y4D1	C3ZUU8	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	RING-type domain-containing protein.	0.790
C3Y4D1_BRAFL	C3ZYQ6_BRAFL	C3Y4D1	C3ZYQ6	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	RING-type domain-containing protein.	0.790
C3YKV1_BRAFL	C3XXM3_BRAFL	C3YKV1	C3XXM3	RING-type domain-containing protein.	Pep3_Vps18 domain-containing protein.	0.998
C3YKV1_BRAFL	C3Y4D1_BRAFL	C3YKV1	C3Y4D1	RING-type domain-containing protein.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.998
C3YKV1_BRAFL	C3YXH4_BRAFL	C3YKV1	C3YXH4	RING-type domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.975
C3YKV1_BRAFL	C3ZIW0_BRAFL	C3YKV1	C3ZIW0	RING-type domain-containing protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.975
C3YKV1_BRAFL	C3ZUU8_BRAFL	C3YKV1	C3ZUU8	RING-type domain-containing protein.	RING-type domain-containing protein.	0.965
C3YKV1_BRAFL	C3ZYQ6_BRAFL	C3YKV1	C3ZYQ6	RING-type domain-containing protein.	RING-type domain-containing protein.	0.965
C3YXH4_BRAFL	C3XXM3_BRAFL	C3YXH4	C3XXM3	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Pep3_Vps18 domain-containing protein.	0.977
C3YXH4_BRAFL	C3Y4D1_BRAFL	C3YXH4	C3Y4D1	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family.	0.975