(11 nodes) JAB1/MPN/MOV34 metalloenzyme domain network (Branchiostoma floridae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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Your Input:
	C3XXY6_BRAFL	MPN domain-containing protein. (311 aa)
	C3ZKZ4_BRAFL	MPN domain-containing protein. (322 aa)
	C3ZBI1_BRAFL	MPN domain-containing protein. (337 aa)
	C3Z8B3_BRAFL	MPN domain-containing protein. (298 aa)
	C3Z0B1_BRAFL	MPN domain-containing protein. (432 aa)
	C3YQB9_BRAFL	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (331 aa)
	C3YJQ0_BRAFL	MPN domain-containing protein. (268 aa)
	C3Y293_BRAFL	MPN domain-containing protein. (168 aa)
	C3XZW8_BRAFL	MPN domain-containing protein. (393 aa)
	C3XZD8_BRAFL	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (277 aa)
	MYSM1	Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation (By similarity). (809 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XXY6_BRAFL	C3XZD8_BRAFL	C3XXY6	C3XZD8	MPN domain-containing protein.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.604
C3XXY6_BRAFL	C3Y293_BRAFL	C3XXY6	C3Y293	MPN domain-containing protein.	MPN domain-containing protein.	0.640
C3XXY6_BRAFL	C3YQB9_BRAFL	C3XXY6	C3YQB9	MPN domain-containing protein.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.807
C3XXY6_BRAFL	C3Z8B3_BRAFL	C3XXY6	C3Z8B3	MPN domain-containing protein.	MPN domain-containing protein.	0.509
C3XXY6_BRAFL	C3ZBI1_BRAFL	C3XXY6	C3ZBI1	MPN domain-containing protein.	MPN domain-containing protein.	0.999
C3XZD8_BRAFL	C3XXY6_BRAFL	C3XZD8	C3XXY6	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	MPN domain-containing protein.	0.604
C3XZD8_BRAFL	C3Y293_BRAFL	C3XZD8	C3Y293	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	MPN domain-containing protein.	0.730
C3XZD8_BRAFL	C3YQB9_BRAFL	C3XZD8	C3YQB9	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
C3XZD8_BRAFL	C3Z0B1_BRAFL	C3XZD8	C3Z0B1	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	MPN domain-containing protein.	0.481
C3XZD8_BRAFL	C3Z8B3_BRAFL	C3XZD8	C3Z8B3	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	MPN domain-containing protein.	0.497
C3XZD8_BRAFL	MYSM1	C3XZD8	B6MUN4	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation (By similarity).	0.538
C3XZW8_BRAFL	C3Y293_BRAFL	C3XZW8	C3Y293	MPN domain-containing protein.	MPN domain-containing protein.	0.436
C3XZW8_BRAFL	C3YQB9_BRAFL	C3XZW8	C3YQB9	MPN domain-containing protein.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.713
C3XZW8_BRAFL	MYSM1	C3XZW8	B6MUN4	MPN domain-containing protein.	Histone H2A deubiquitinase MYSM1; Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation (By similarity).	0.733
C3Y293_BRAFL	C3XXY6_BRAFL	C3Y293	C3XXY6	MPN domain-containing protein.	MPN domain-containing protein.	0.640
C3Y293_BRAFL	C3XZD8_BRAFL	C3Y293	C3XZD8	MPN domain-containing protein.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.730
C3Y293_BRAFL	C3XZW8_BRAFL	C3Y293	C3XZW8	MPN domain-containing protein.	MPN domain-containing protein.	0.436
C3Y293_BRAFL	C3YQB9_BRAFL	C3Y293	C3YQB9	MPN domain-containing protein.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.823
C3Y293_BRAFL	C3Z8B3_BRAFL	C3Y293	C3Z8B3	MPN domain-containing protein.	MPN domain-containing protein.	0.998
C3Y293_BRAFL	C3ZBI1_BRAFL	C3Y293	C3ZBI1	MPN domain-containing protein.	MPN domain-containing protein.	0.889