(63 nodes) Pyridoxal phosphate-dependent transferase, major domain network (Branchiostoma floridae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	KYNU	Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (467 aa)
	C3ZH05_BRAFL	Uncharacterized protein. (525 aa)
	C3ZMD6_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
	C3ZMS9_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
	C3ZQY6_BRAFL	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1218 aa)
	C3ZRR8_BRAFL	Uncharacterized protein. (489 aa)
	C3ZS18_BRAFL	Uncharacterized protein. (480 aa)
	C3XUB6_BRAFL	Aminotran_5 domain-containing protein. (402 aa)
	C3XWF9_BRAFL	Uncharacterized protein. (1156 aa)
	C3XWI3_BRAFL	Aminotran_1_2 domain-containing protein. (195 aa)
	C3XSQ5_BRAFL	SHMT domain-containing protein. (406 aa)
	C3XR82_BRAFL	Uncharacterized protein. (472 aa)
	C3XR74_BRAFL	Aminotran_1_2 domain-containing protein. (483 aa)
	C3XPW2_BRAFL	Serine--pyruvate aminotransferase. (348 aa)
	C3ZZL9_BRAFL	Aspartate aminotransferase. (387 aa)
	C3ZZF6_BRAFL	Uncharacterized protein. (1318 aa)
	C3ZZ27_BRAFL	Uncharacterized protein. (484 aa)
	C3ZXC6_BRAFL	Uncharacterized protein. (549 aa)
	C3ZWR9_BRAFL	Uncharacterized protein. (489 aa)
	C3ZVC9_BRAFL	Aminotran_5 domain-containing protein. (456 aa)
	C3ZV83_BRAFL	Aminotran_1_2 domain-containing protein. (486 aa)
	C3ZTJ5_BRAFL	C2H2-type domain-containing protein. (676 aa)
	C3XSS1_BRAFL	Uncharacterized protein. (538 aa)
	C3XWS0_BRAFL	Uncharacterized protein. (424 aa)
	C3Y062_BRAFL	Uncharacterized protein. (566 aa)
	C3Y0B7_BRAFL	Serine--pyruvate aminotransferase. (402 aa)
	C3Y126_BRAFL	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (509 aa)
	C3Y4I9_BRAFL	Uncharacterized protein. (364 aa)
	C3Y5S8_BRAFL	Uncharacterized protein. (893 aa)
	C3Y6S2_BRAFL	Uncharacterized protein. (142 aa)
	C3Y6S3_BRAFL	Uncharacterized protein. (136 aa)
	C3Y6S5_BRAFL	Uncharacterized protein. (502 aa)
	C3Y9H0_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (348 aa)
	C3YE71_BRAFL	Uncharacterized protein. (532 aa)
	C3YFT1_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (437 aa)
	C3YHC7_BRAFL	Uncharacterized protein. (939 aa)
	C3YI08_BRAFL	Ig-like domain-containing protein. (768 aa)
	C3YI82_BRAFL	HPPK domain-containing protein. (737 aa)
	C3YIV5_BRAFL	Aminotran_1_2 domain-containing protein. (412 aa)
	C3YJ38_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (416 aa)
	C3YPX4_BRAFL	Aminotran_1_2 domain-containing protein. (449 aa)
	C3YTG3_BRAFL	Uncharacterized protein. (408 aa)
	C3YWW0_BRAFL	Aminotran_1_2 domain-containing protein. (394 aa)
	C3YZ30_BRAFL	Uncharacterized protein. (562 aa)
	C3YZI1_BRAFL	Aminotran_1_2 domain-containing protein. (214 aa)
	C3Z044_BRAFL	Uncharacterized protein. (393 aa)
	C3Z0P5_BRAFL	Uncharacterized protein. (469 aa)
	C3Z0U0_BRAFL	Phosphoserine aminotransferase. (368 aa)
	C3Z4G4_BRAFL	Uncharacterized protein. (563 aa)
	C3Z4N4_BRAFL	Aminotran_5 domain-containing protein. (618 aa)
	C3Z4N5_BRAFL	Aminotran_5 domain-containing protein. (860 aa)
	C3Z7B2_BRAFL	Uncharacterized protein. (422 aa)
	C3Z7G1_BRAFL	Uncharacterized protein. (685 aa)
	C3Z7V3_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (344 aa)
	C3ZAH6_BRAFL	5-aminolevulinate synthase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
	C3ZBP9_BRAFL	Beta_elim_lyase domain-containing protein. (360 aa)
	C3ZBQ6_BRAFL	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
	C3ZBR3_BRAFL	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. (436 aa)
	C3ZGY8_BRAFL	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (905 aa)
	C3ZG28_BRAFL	Aminotran_1_2 domain-containing protein. (431 aa)
	C3ZFM1_BRAFL	Aminotran_1_2 domain-containing protein. (468 aa)
	C3ZED9_BRAFL	Uncharacterized protein. (479 aa)
	C3ZCP5_BRAFL	Uncharacterized protein. (373 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPW2_BRAFL	C3XSQ5_BRAFL	C3XPW2	C3XSQ5	Serine--pyruvate aminotransferase.	SHMT domain-containing protein.	0.696
C3XPW2_BRAFL	C3Y126_BRAFL	C3XPW2	C3Y126	Serine--pyruvate aminotransferase.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.696
C3XPW2_BRAFL	C3Z0U0_BRAFL	C3XPW2	C3Z0U0	Serine--pyruvate aminotransferase.	Phosphoserine aminotransferase.	0.497
C3XPW2_BRAFL	C3ZBP9_BRAFL	C3XPW2	C3ZBP9	Serine--pyruvate aminotransferase.	Beta_elim_lyase domain-containing protein.	0.925
C3XPW2_BRAFL	C3ZBQ6_BRAFL	C3XPW2	C3ZBQ6	Serine--pyruvate aminotransferase.	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.712
C3XPW2_BRAFL	C3ZBR3_BRAFL	C3XPW2	C3ZBR3	Serine--pyruvate aminotransferase.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.459
C3XPW2_BRAFL	C3ZV83_BRAFL	C3XPW2	C3ZV83	Serine--pyruvate aminotransferase.	Aminotran_1_2 domain-containing protein.	0.545
C3XPW2_BRAFL	C3ZZF6_BRAFL	C3XPW2	C3ZZF6	Serine--pyruvate aminotransferase.	Uncharacterized protein.	0.540
C3XPW2_BRAFL	C3ZZL9_BRAFL	C3XPW2	C3ZZL9	Serine--pyruvate aminotransferase.	Aspartate aminotransferase.	0.403
C3XR74_BRAFL	C3XR82_BRAFL	C3XR74	C3XR82	Aminotran_1_2 domain-containing protein.	Uncharacterized protein.	0.546
C3XR74_BRAFL	C3Y126_BRAFL	C3XR74	C3Y126	Aminotran_1_2 domain-containing protein.	Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.	0.840
C3XR74_BRAFL	C3ZFM1_BRAFL	C3XR74	C3ZFM1	Aminotran_1_2 domain-containing protein.	Aminotran_1_2 domain-containing protein.	0.995
C3XR74_BRAFL	C3ZTJ5_BRAFL	C3XR74	C3ZTJ5	Aminotran_1_2 domain-containing protein.	C2H2-type domain-containing protein.	0.908
C3XR82_BRAFL	C3XR74_BRAFL	C3XR82	C3XR74	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.546
C3XR82_BRAFL	C3ZFM1_BRAFL	C3XR82	C3ZFM1	Uncharacterized protein.	Aminotran_1_2 domain-containing protein.	0.961
C3XSQ5_BRAFL	C3XPW2_BRAFL	C3XSQ5	C3XPW2	SHMT domain-containing protein.	Serine--pyruvate aminotransferase.	0.696
C3XSQ5_BRAFL	C3Y0B7_BRAFL	C3XSQ5	C3Y0B7	SHMT domain-containing protein.	Serine--pyruvate aminotransferase.	0.695
C3XSQ5_BRAFL	C3Z0U0_BRAFL	C3XSQ5	C3Z0U0	SHMT domain-containing protein.	Phosphoserine aminotransferase.	0.714
C3XSQ5_BRAFL	C3ZBP9_BRAFL	C3XSQ5	C3ZBP9	SHMT domain-containing protein.	Beta_elim_lyase domain-containing protein.	0.542
C3XSQ5_BRAFL	C3ZGY8_BRAFL	C3XSQ5	C3ZGY8	SHMT domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.447