(14 nodes) PINK1-PRKN Mediated Mitophagy network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3YZR5_BRAFL	Uncharacterized protein. (600 aa)
	C3Y2C9_BRAFL	Uncharacterized protein. (609 aa)
	C3XPY9_BRAFL	Protein kinase domain-containing protein. (347 aa)
	C3XS07_BRAFL	Uncharacterized protein. (516 aa)
	C3XU59_BRAFL	Uncharacterized protein. (120 aa)
	C3XVY8_BRAFL	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (414 aa)
	C3XXF8_BRAFL	Uncharacterized protein. (554 aa)
	C3Y0N4_BRAFL	Uncharacterized protein. (337 aa)
	C3YEH1_BRAFL	Uncharacterized protein. (142 aa)
	C3YF66_BRAFL	Uncharacterized protein. (155 aa)
	C3Z502_BRAFL	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (434 aa)
	C3ZI98_BRAFL	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (776 aa)
	C3ZJI8_BRAFL	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (86 aa)
	C3ZNT2_BRAFL	Autophagy protein 5; Involved in autophagic vesicle formation. (261 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPY9_BRAFL	C3XS07_BRAFL	C3XPY9	C3XS07	Protein kinase domain-containing protein.	Uncharacterized protein.	0.661
C3XPY9_BRAFL	C3XVY8_BRAFL	C3XPY9	C3XVY8	Protein kinase domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.971
C3XPY9_BRAFL	C3XXF8_BRAFL	C3XPY9	C3XXF8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.754
C3XPY9_BRAFL	C3Y0N4_BRAFL	C3XPY9	C3Y0N4	Protein kinase domain-containing protein.	Uncharacterized protein.	0.766
C3XPY9_BRAFL	C3Y2C9_BRAFL	C3XPY9	C3Y2C9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.971
C3XPY9_BRAFL	C3YEH1_BRAFL	C3XPY9	C3YEH1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.657
C3XPY9_BRAFL	C3YF66_BRAFL	C3XPY9	C3YF66	Protein kinase domain-containing protein.	Uncharacterized protein.	0.639
C3XPY9_BRAFL	C3YZR5_BRAFL	C3XPY9	C3YZR5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.971
C3XPY9_BRAFL	C3Z502_BRAFL	C3XPY9	C3Z502	Protein kinase domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.997
C3XPY9_BRAFL	C3ZI98_BRAFL	C3XPY9	C3ZI98	Protein kinase domain-containing protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.990
C3XPY9_BRAFL	C3ZJI8_BRAFL	C3XPY9	C3ZJI8	Protein kinase domain-containing protein.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.570
C3XPY9_BRAFL	C3ZNT2_BRAFL	C3XPY9	C3ZNT2	Protein kinase domain-containing protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.706
C3XS07_BRAFL	C3XPY9_BRAFL	C3XS07	C3XPY9	Uncharacterized protein.	Protein kinase domain-containing protein.	0.661
C3XS07_BRAFL	C3XVY8_BRAFL	C3XS07	C3XVY8	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.544
C3XS07_BRAFL	C3Y0N4_BRAFL	C3XS07	C3Y0N4	Uncharacterized protein.	Uncharacterized protein.	0.985
C3XS07_BRAFL	C3YF66_BRAFL	C3XS07	C3YF66	Uncharacterized protein.	Uncharacterized protein.	0.986
C3XS07_BRAFL	C3Z502_BRAFL	C3XS07	C3Z502	Uncharacterized protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.544
C3XS07_BRAFL	C3ZI98_BRAFL	C3XS07	C3ZI98	Uncharacterized protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.578
C3XU59_BRAFL	C3XXF8_BRAFL	C3XU59	C3XXF8	Uncharacterized protein.	Uncharacterized protein.	0.981
C3XU59_BRAFL	C3Y2C9_BRAFL	C3XU59	C3Y2C9	Uncharacterized protein.	Uncharacterized protein.	0.635