(14 nodes) VEGFR2 mediated vascular permeability network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3YC71_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	C3Z7M9_BRAFL	WD_REPEATS_REGION domain-containing protein. (285 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3Z873_BRAFL	Non-specific serine/threonine protein kinase. (415 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZCQ4_BRAFL	Uncharacterized protein. (338 aa)
	C3ZCQ5_BRAFL	SIN1_PH domain-containing protein. (147 aa)
	C3ZCV0_BRAFL	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (253 aa)
	C3ZJ41_BRAFL	Uncharacterized protein. (1669 aa)
	C3ZLL3_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1049 aa)
	C3ZLL7_BRAFL	DUF3385 domain-containing protein. (1400 aa)
	C3ZT37_BRAFL	Uncharacterized protein. (858 aa)
	Wnt3	Protein kinase domain-containing protein. (318 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3YC71_BRAFL	C3ZCQ4_BRAFL	C3YC71	C3ZCQ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.443
C3YC71_BRAFL	C3ZLL3_BRAFL	C3YC71	C3ZLL3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.443
C3YC71_BRAFL	C3ZLL7_BRAFL	C3YC71	C3ZLL7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	DUF3385 domain-containing protein.	0.443
C3Z7M9_BRAFL	C3ZCQ4_BRAFL	C3Z7M9	C3ZCQ4	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.999
C3Z7M9_BRAFL	C3ZCQ5_BRAFL	C3Z7M9	C3ZCQ5	WD_REPEATS_REGION domain-containing protein.	SIN1_PH domain-containing protein.	0.986
C3Z7M9_BRAFL	C3ZJ41_BRAFL	C3Z7M9	C3ZJ41	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.997
C3Z7M9_BRAFL	C3ZLL3_BRAFL	C3Z7M9	C3ZLL3	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.986
C3Z7M9_BRAFL	C3ZLL7_BRAFL	C3Z7M9	C3ZLL7	WD_REPEATS_REGION domain-containing protein.	DUF3385 domain-containing protein.	0.997
C3Z851_BRAFL	C3ZB87_BRAFL	C3Z851	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z851_BRAFL	C3ZB88_BRAFL	C3Z851	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3Z851_BRAFL	C3ZT37_BRAFL	C3Z851	C3ZT37	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.682
C3Z873_BRAFL	C3ZT37_BRAFL	C3Z873	C3ZT37	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.685
C3ZB87_BRAFL	C3Z851_BRAFL	C3ZB87	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB87_BRAFL	C3ZB88_BRAFL	C3ZB87	C3ZB88	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZB87_BRAFL	C3ZT37_BRAFL	C3ZB87	C3ZT37	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.454
C3ZB88_BRAFL	C3Z851_BRAFL	C3ZB88	C3Z851	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.904
C3ZB88_BRAFL	C3ZB87_BRAFL	C3ZB88	C3ZB87	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.900
C3ZB88_BRAFL	C3ZT37_BRAFL	C3ZB88	C3ZT37	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Uncharacterized protein.	0.454
C3ZCQ4_BRAFL	C3YC71_BRAFL	C3ZCQ4	C3YC71	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.443
C3ZCQ4_BRAFL	C3Z7M9_BRAFL	C3ZCQ4	C3Z7M9	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.999