(45 nodes) Resolution of D-loop Structures through Holliday Junction Intermediates network (Branchiostoma floridae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	C3YV14_BRAFL	Helicase C-terminal domain-containing protein. (503 aa)
	C3YVY6_BRAFL	RECA_2 domain-containing protein. (103 aa)
	C3YW39_BRAFL	Uncharacterized protein. (2614 aa)
	C3YZM5_BRAFL	Uncharacterized protein. (453 aa)
	C3Z419_BRAFL	GIY-YIG domain-containing protein. (155 aa)
	C3Z4R4_BRAFL	TPR_REGION domain-containing protein. (698 aa)
	C3Z6I4_BRAFL	Uncharacterized protein. (107 aa)
	C3Z6W7_BRAFL	ERCC4 domain-containing protein. (598 aa)
	C3Z734_BRAFL	Uncharacterized protein. (275 aa)
	C3Z741_BRAFL	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (346 aa)
	C3Z742_BRAFL	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (684 aa)
	C3ZAS6_BRAFL	Helicase C-terminal domain-containing protein. (606 aa)
	C3ZAS8_BRAFL	Uncharacterized protein. (1098 aa)
	C3ZBQ9_BRAFL	Helicase ATP-binding domain-containing protein. (270 aa)
	C3ZEN4_BRAFL	Mre11_DNA_bind domain-containing protein. (441 aa)
	C3ZF00_BRAFL	Uncharacterized protein. (790 aa)
	C3ZHI0_BRAFL	Helicase ATP-binding domain-containing protein. (504 aa)
	C3ZMX5_BRAFL	Uncharacterized protein. (1057 aa)
	C3ZR83_BRAFL	Uncharacterized protein. (459 aa)
	C3ZTJ4_BRAFL	Uncharacterized protein. (502 aa)
	C3ZZH4_BRAFL	Uncharacterized protein. (541 aa)
	C4A088_BRAFL	BTB domain-containing protein. (2428 aa)
	C3YWA5_BRAFL	AAA_23 domain-containing protein. (187 aa)
	C3XPU5_BRAFL	ERCC4 domain-containing protein. (1825 aa)
	C3XT78_BRAFL	Uncharacterized protein. (458 aa)
	C3XU62_BRAFL	Uncharacterized protein. (1010 aa)
	C3XXY9_BRAFL	Uncharacterized protein. (145 aa)
	C3Y0V4_BRAFL	ERCC4 domain-containing protein. (268 aa)
	C3Y0V8_BRAFL	ERCC4 domain-containing protein. (600 aa)
	C3Y0V9_BRAFL	Uncharacterized protein. (343 aa)
	C3Y4F4_BRAFL	Uncharacterized protein. (676 aa)
	C3Y4R4_BRAFL	Helicase C-terminal domain-containing protein. (392 aa)
	C3Y696_BRAFL	Uncharacterized protein. (304 aa)
	C3Y8N4_BRAFL	Helicase C-terminal domain-containing protein. (591 aa)
	C3YBR3_BRAFL	tRNA-synt_2 domain-containing protein. (151 aa)
	C3YFG1_BRAFL	FHA domain-containing protein. (721 aa)
	C3YH71_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (553 aa)
	C3YH73_BRAFL	FAT domain-containing protein. (2357 aa)
	C3YI31_BRAFL	DUF1767 domain-containing protein. (184 aa)
	C3YKR1_BRAFL	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (666 aa)
	C3YNS7_BRAFL	Uncharacterized protein. (277 aa)
	C3YV06_BRAFL	CCHC-type domain-containing protein. (999 aa)
	C3YV08_BRAFL	Uncharacterized protein. (196 aa)
	C3YV10_BRAFL	Uncharacterized protein. (133 aa)
	C3YV12_BRAFL	Helicase C-terminal domain-containing protein. (807 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPU5_BRAFL	C3XXY9_BRAFL	C3XPU5	C3XXY9	ERCC4 domain-containing protein.	Uncharacterized protein.	0.635
C3XPU5_BRAFL	C3Y0V4_BRAFL	C3XPU5	C3Y0V4	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.540
C3XPU5_BRAFL	C3Y0V8_BRAFL	C3XPU5	C3Y0V8	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.540
C3XPU5_BRAFL	C3Y0V9_BRAFL	C3XPU5	C3Y0V9	ERCC4 domain-containing protein.	Uncharacterized protein.	0.540
C3XPU5_BRAFL	C3Y4F4_BRAFL	C3XPU5	C3Y4F4	ERCC4 domain-containing protein.	Uncharacterized protein.	0.474
C3XPU5_BRAFL	C3YBR3_BRAFL	C3XPU5	C3YBR3	ERCC4 domain-containing protein.	tRNA-synt_2 domain-containing protein.	0.586
C3XPU5_BRAFL	C3YFG1_BRAFL	C3XPU5	C3YFG1	ERCC4 domain-containing protein.	FHA domain-containing protein.	0.443
C3XPU5_BRAFL	C3YH71_BRAFL	C3XPU5	C3YH71	ERCC4 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.402
C3XPU5_BRAFL	C3YH73_BRAFL	C3XPU5	C3YH73	ERCC4 domain-containing protein.	FAT domain-containing protein.	0.402
C3XPU5_BRAFL	C3YI31_BRAFL	C3XPU5	C3YI31	ERCC4 domain-containing protein.	DUF1767 domain-containing protein.	0.661
C3XPU5_BRAFL	C3YVY6_BRAFL	C3XPU5	C3YVY6	ERCC4 domain-containing protein.	RECA_2 domain-containing protein.	0.675
C3XPU5_BRAFL	C3YW39_BRAFL	C3XPU5	C3YW39	ERCC4 domain-containing protein.	Uncharacterized protein.	0.485
C3XPU5_BRAFL	C3YWA5_BRAFL	C3XPU5	C3YWA5	ERCC4 domain-containing protein.	AAA_23 domain-containing protein.	0.478
C3XPU5_BRAFL	C3Z419_BRAFL	C3XPU5	C3Z419	ERCC4 domain-containing protein.	GIY-YIG domain-containing protein.	0.574
C3XPU5_BRAFL	C3Z4R4_BRAFL	C3XPU5	C3Z4R4	ERCC4 domain-containing protein.	TPR_REGION domain-containing protein.	0.525
C3XPU5_BRAFL	C3Z6W7_BRAFL	C3XPU5	C3Z6W7	ERCC4 domain-containing protein.	ERCC4 domain-containing protein.	0.960
C3XPU5_BRAFL	C3Z734_BRAFL	C3XPU5	C3Z734	ERCC4 domain-containing protein.	Uncharacterized protein.	0.525
C3XPU5_BRAFL	C3Z741_BRAFL	C3XPU5	C3Z741	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.594
C3XPU5_BRAFL	C3Z742_BRAFL	C3XPU5	C3Z742	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.594
C3XPU5_BRAFL	C3ZEN4_BRAFL	C3XPU5	C3ZEN4	ERCC4 domain-containing protein.	Mre11_DNA_bind domain-containing protein.	0.518