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| | C3ZB54_BRAFL | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (183 aa) |
| | C3ZA86_BRAFL | PCI domain-containing protein. (389 aa) |
| | C3Z9J2_BRAFL | Uncharacterized protein. (337 aa) |
| | C3Z9E7_BRAFL | Proteasome subunit beta. (235 aa) |
| | C3Z8E0_BRAFL | PCI domain-containing protein. (512 aa) |
| | C3Z899_BRAFL | AAA domain-containing protein. (364 aa) |
| | C3Z7P4_BRAFL | DNA ligase. (952 aa) |
| | C3Z7L1_BRAFL | PCI domain-containing protein. (452 aa) |
| | UBE2S_BRAFL | Ubiquitin-conjugating enzyme E2 S; Catalyzes the covalent attachment of ubiquitin to other proteins. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating polyubiquitin chains initiated by the E2 enzyme UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. (213 aa) |
| | C3Z568_BRAFL | Proteasome subunit beta. (276 aa) |
| | C3Z4T9_BRAFL | DNA helicase; Belongs to the MCM family. (731 aa) |
| | C3Z3L7_BRAFL | PCI domain-containing protein. (256 aa) |
| | C3Z3L5_BRAFL | AAA domain-containing protein; Belongs to the AAA ATPase family. (392 aa) |
| | C3Z346_BRAFL | Proteasome subunit alpha type. (262 aa) |
| | C3Z2M9_BRAFL | AAA_16 domain-containing protein. (227 aa) |
| | C3Z2M7_BRAFL | AAA_16 domain-containing protein. (456 aa) |
| | C3Z0Z0_BRAFL | Proteasome subunit alpha type. (252 aa) |
| | C3Z068_BRAFL | GLTSCR1 domain-containing protein. (1731 aa) |
| | C3Z060_BRAFL | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (397 aa) |
| | C3YZV0_BRAFL | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (320 aa) |
| | C3YZR5_BRAFL | Uncharacterized protein. (600 aa) |
| | C3YZJ9_BRAFL | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (181 aa) |
| | C3YYS3_BRAFL | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (598 aa) |
| | C3YYK3_BRAFL | TPR_REGION domain-containing protein. (854 aa) |
| | C3YYJ5_BRAFL | Uncharacterized protein. (492 aa) |
| | C3YW11_BRAFL | Proteasome subunit beta. (205 aa) |
| | C3YUN6_BRAFL | Uncharacterized protein. (118 aa) |
| | C3YTV7_BRAFL | CULLIN_2 domain-containing protein; Belongs to the cullin family. (818 aa) |
| | C3YQ31_BRAFL | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (474 aa) |
| | C3YP57_BRAFL | Uncharacterized protein; Belongs to the SKP1 family. (196 aa) |
| | C3YM20_BRAFL | F-box domain-containing protein. (421 aa) |
| | C3YL40_BRAFL | DNA helicase; Belongs to the MCM family. (816 aa) |
| | C3YK31_BRAFL | Uncharacterized protein. (537 aa) |
| | C3YIL9_BRAFL | MCM domain-containing protein; Belongs to the MCM family. (678 aa) |
| | C3YIF0_BRAFL | Uncharacterized protein. (721 aa) |
| | C3YGW3_BRAFL | Uncharacterized protein. (1825 aa) |
| | C3YGH8_BRAFL | Uncharacterized protein. (250 aa) |
| | C3YEU3_BRAFL | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (372 aa) |
| | C3YEL7_BRAFL | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (540 aa) |
| | C3YEL6_BRAFL | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (579 aa) |
| | C3YEG7_BRAFL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa) |
| | C3YEG2_BRAFL | ANK_REP_REGION domain-containing protein. (93 aa) |
| | C3YDQ6_BRAFL | Proteasome subunit beta; Belongs to the peptidase T1B family. (258 aa) |
| | C3YDK8_BRAFL | AAA domain-containing protein. (362 aa) |
| | C3YCQ9_BRAFL | Uncharacterized protein. (545 aa) |
| | C3YBG7_BRAFL | RING-type domain-containing protein. (89 aa) |
| | C3YB87_BRAFL | CULLIN_2 domain-containing protein; Belongs to the cullin family. (771 aa) |
| | C3YAI9_BRAFL | DNA helicase; Belongs to the MCM family. (892 aa) |
| | C3YAA1_BRAFL | Uncharacterized protein. (521 aa) |
| | C3Y9V2_BRAFL | CBFD_NFYB_HMF domain-containing protein. (115 aa) |
| | C3Y9F3_BRAFL | Uncharacterized protein. (449 aa) |
| | C3Y9A3_BRAFL | ATPase_AAA_core domain-containing protein. (2025 aa) |
| | C3Y895_BRAFL | AAA domain-containing protein; Belongs to the AAA ATPase family. (407 aa) |
| | C3Y5T5_BRAFL | VWFA domain-containing protein. (401 aa) |
| | C3Y5L7_BRAFL | AAA domain-containing protein; Belongs to the AAA ATPase family. (417 aa) |
| | C3Y5K6_BRAFL | DNA polymerase. (1286 aa) |
| | C3Y542_BRAFL | DUF4203 domain-containing protein. (513 aa) |
| | C3Y4Y4_BRAFL | Uncharacterized protein. (223 aa) |
| | C3Y4Y3_BRAFL | BRCT domain-containing protein. (756 aa) |
| | C3Y3Y6_BRAFL | Uncharacterized protein. (675 aa) |
| | C3Y3A4_BRAFL | Uncharacterized protein. (110 aa) |
| | C3Y322_BRAFL | Uncharacterized protein. (503 aa) |
| | C3Y2C9_BRAFL | Uncharacterized protein. (609 aa) |
| | C3Y0U6_BRAFL | MCM domain-containing protein; Belongs to the MCM family. (844 aa) |
| | C3Y0R7_BRAFL | ANAPC5 domain-containing protein. (747 aa) |
| | C3Y0L2_BRAFL | APC1_C domain-containing protein. (2078 aa) |
| | C3Y0B8_BRAFL | Proteasome subunit alpha type. (255 aa) |
| | C3XZT5_BRAFL | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (189 aa) |
| | C3XZ66_BRAFL | Proteasome subunit alpha type. (246 aa) |
| | C3XYM1_BRAFL | AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa) |
| | C3XXY6_BRAFL | MPN domain-containing protein. (311 aa) |
| | C3XXN0_BRAFL | RING-type domain-containing protein. (111 aa) |
| | C3XXK6_BRAFL | AAA domain-containing protein. (356 aa) |
| | C3XVA8_BRAFL | Uncharacterized protein. (115 aa) |
| | C3XTX5_BRAFL | Sld5 domain-containing protein. (207 aa) |
| | C3XSS5_BRAFL | Proteasome subunit alpha type. (212 aa) |
| | C3XS01_BRAFL | AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa) |
| | C3XR78_BRAFL | Sld5 domain-containing protein. (196 aa) |
| | C3ZB79_BRAFL | MCM domain-containing protein; Belongs to the MCM family. (473 aa) |
| | C3ZB80_BRAFL | Uncharacterized protein. (354 aa) |
| | C3ZBI1_BRAFL | MPN domain-containing protein. (337 aa) |
| | C3ZBI7_BRAFL | Uncharacterized protein. (135 aa) |
| | C3ZBI8_BRAFL | Uncharacterized protein. (113 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | C3ZBU1_BRAFL | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (412 aa) |
| | C3ZD95_BRAFL | Uncharacterized protein. (499 aa) |
| | C3ZEE6_BRAFL | DNA polymerase. (1526 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (279 aa) |
| | MCM7-2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (457 aa) |
| | C3ZEX5_BRAFL | Uncharacterized protein. (130 aa) |
| | C3ZF97_BRAFL | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa) |
| | C3ZFB5_BRAFL | BTB domain-containing protein. (538 aa) |
| | C3ZFR4_BRAFL | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (1032 aa) |
| | C3ZHV8_BRAFL | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (265 aa) |
| | C3ZHV9_BRAFL | Uncharacterized protein. (256 aa) |
| | C3ZI15_BRAFL | Proteasome subunit beta. (201 aa) |
| | C3ZIC3_BRAFL | Proteasome subunit beta. (232 aa) |
| | Hsd11b1F | PDZ domain-containing protein. (199 aa) |
| | C3ZJN9_BRAFL | Uncharacterized protein. (1786 aa) |
| | C3ZKU4_BRAFL | Uncharacterized protein. (103 aa) |
| | C3ZL26_BRAFL | AAA domain-containing protein. (329 aa) |
| | C3ZLJ0_BRAFL | ORC_WH_C domain-containing protein. (875 aa) |
| | C3ZLP9_BRAFL | TPR_REGION domain-containing protein. (575 aa) |
| | C3ZN04_BRAFL | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (541 aa) |
| | C3ZN90_BRAFL | Uncharacterized protein. (285 aa) |
| | C3ZPM6_BRAFL | PCI domain-containing protein. (427 aa) |
| | C3ZPP8_BRAFL | Proteasome subunit alpha type. (241 aa) |
| | C3ZPW4_BRAFL | Uncharacterized protein. (213 aa) |
| | C3ZPX9_BRAFL | PCI domain-containing protein. (377 aa) |
| | C3ZR59_BRAFL | AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa) |
| | C3ZRF2_BRAFL | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa) |
| | C3ZS90_BRAFL | ANK_REP_REGION domain-containing protein. (145 aa) |
| | C3ZSS5_BRAFL | DNA helicase; Belongs to the MCM family. (690 aa) |
| | C3ZT90_BRAFL | Uncharacterized protein. (410 aa) |
| | C3ZWY4_BRAFL | CBFD_NFYB_HMF domain-containing protein. (153 aa) |
