(39 nodes) Ubiquitin-dependent degradation of Cyclin D network (Branchiostoma floridae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3ZPW4_BRAFL	Uncharacterized protein. (213 aa)
	C3ZPX9_BRAFL	PCI domain-containing protein. (377 aa)
	C3XS01_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (441 aa)
	C3XSS5_BRAFL	Proteasome subunit alpha type. (212 aa)
	C3XXY6_BRAFL	MPN domain-containing protein. (311 aa)
	C3XYM1_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa)
	C3XZ66_BRAFL	Proteasome subunit alpha type. (246 aa)
	C3Y0B8_BRAFL	Proteasome subunit alpha type. (255 aa)
	C3Y2C9_BRAFL	Uncharacterized protein. (609 aa)
	C3Y322_BRAFL	Uncharacterized protein. (503 aa)
	C3Y5L7_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (417 aa)
	C3Y5T5_BRAFL	VWFA domain-containing protein. (401 aa)
	C3Y895_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (407 aa)
	C3YDQ6_BRAFL	Proteasome subunit beta; Belongs to the peptidase T1B family. (258 aa)
	C3YEG2_BRAFL	ANK_REP_REGION domain-containing protein. (93 aa)
	C3YGW3_BRAFL	Uncharacterized protein. (1825 aa)
	C3YW11_BRAFL	Proteasome subunit beta. (205 aa)
	C3ZR59_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (405 aa)
	C3YZR5_BRAFL	Uncharacterized protein. (600 aa)
	C3Z0Z0_BRAFL	Proteasome subunit alpha type. (252 aa)
	C3Z346_BRAFL	Proteasome subunit alpha type. (262 aa)
	C3Z3L5_BRAFL	AAA domain-containing protein; Belongs to the AAA ATPase family. (392 aa)
	C3Z3L7_BRAFL	PCI domain-containing protein. (256 aa)
	C3Z568_BRAFL	Proteasome subunit beta. (276 aa)
	C3Z7L1_BRAFL	PCI domain-containing protein. (452 aa)
	C3Z8E0_BRAFL	PCI domain-containing protein. (512 aa)
	C3Z9E7_BRAFL	Proteasome subunit beta. (235 aa)
	C3ZA86_BRAFL	PCI domain-containing protein. (389 aa)
	C3ZBI1_BRAFL	MPN domain-containing protein. (337 aa)
	C3ZBI7_BRAFL	Uncharacterized protein. (135 aa)
	C3ZBI8_BRAFL	Uncharacterized protein. (113 aa)
	C3ZF97_BRAFL	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (959 aa)
	C3ZI15_BRAFL	Proteasome subunit beta. (201 aa)
	C3ZS90_BRAFL	ANK_REP_REGION domain-containing protein. (145 aa)
	C3ZIC3_BRAFL	Proteasome subunit beta. (232 aa)
	Hsd11b1F	PDZ domain-containing protein. (199 aa)
	C3ZN90_BRAFL	Uncharacterized protein. (285 aa)
	C3ZPM6_BRAFL	PCI domain-containing protein. (427 aa)
	C3ZPP8_BRAFL	Proteasome subunit alpha type. (241 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XS01_BRAFL	C3XSS5_BRAFL	C3XS01	C3XSS5	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.999
C3XS01_BRAFL	C3XXY6_BRAFL	C3XS01	C3XXY6	AAA domain-containing protein; Belongs to the AAA ATPase family.	MPN domain-containing protein.	0.999
C3XS01_BRAFL	C3XYM1_BRAFL	C3XS01	C3XYM1	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
C3XS01_BRAFL	C3XZ66_BRAFL	C3XS01	C3XZ66	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.999
C3XS01_BRAFL	C3Y0B8_BRAFL	C3XS01	C3Y0B8	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.999
C3XS01_BRAFL	C3Y2C9_BRAFL	C3XS01	C3Y2C9	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.941
C3XS01_BRAFL	C3Y322_BRAFL	C3XS01	C3Y322	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.994
C3XS01_BRAFL	C3Y5L7_BRAFL	C3XS01	C3Y5L7	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
C3XS01_BRAFL	C3Y5T5_BRAFL	C3XS01	C3Y5T5	AAA domain-containing protein; Belongs to the AAA ATPase family.	VWFA domain-containing protein.	0.999
C3XS01_BRAFL	C3Y895_BRAFL	C3XS01	C3Y895	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
C3XS01_BRAFL	C3YDQ6_BRAFL	C3XS01	C3YDQ6	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit beta; Belongs to the peptidase T1B family.	0.999
C3XS01_BRAFL	C3YEG2_BRAFL	C3XS01	C3YEG2	AAA domain-containing protein; Belongs to the AAA ATPase family.	ANK_REP_REGION domain-containing protein.	0.929
C3XS01_BRAFL	C3YGW3_BRAFL	C3XS01	C3YGW3	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.764
C3XS01_BRAFL	C3YW11_BRAFL	C3XS01	C3YW11	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.998
C3XS01_BRAFL	C3YZR5_BRAFL	C3XS01	C3YZR5	AAA domain-containing protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.941
C3XS01_BRAFL	C3Z0Z0_BRAFL	C3XS01	C3Z0Z0	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.999
C3XS01_BRAFL	C3Z346_BRAFL	C3XS01	C3Z346	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit alpha type.	0.999
C3XS01_BRAFL	C3Z3L5_BRAFL	C3XS01	C3Z3L5	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
C3XS01_BRAFL	C3Z3L7_BRAFL	C3XS01	C3Z3L7	AAA domain-containing protein; Belongs to the AAA ATPase family.	PCI domain-containing protein.	0.999
C3XS01_BRAFL	C3Z568_BRAFL	C3XS01	C3Z568	AAA domain-containing protein; Belongs to the AAA ATPase family.	Proteasome subunit beta.	0.993