(23 nodes) RET signaling network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3YT92_BRAFL	cAMP-dependent protein kinase; Belongs to the protein kinase superfamily. (369 aa)
	C3YMZ3_BRAFL	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	C3YM66_BRAFL	Protein kinase domain-containing protein. (307 aa)
	C3YM64_BRAFL	Protein kinase domain-containing protein. (309 aa)
	C3YIM5_BRAFL	Protein kinase domain-containing protein. (171 aa)
	C3YFF4_BRAFL	Protein kinase domain-containing protein. (219 aa)
	C3YA44_BRAFL	Uncharacterized protein. (1022 aa)
	C3Y918_BRAFL	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (248 aa)
	C3Y6Q0_BRAFL	PH domain-containing protein. (455 aa)
	C3Y807_BRAFL	Uncharacterized protein. (780 aa)
	C3Y4J7_BRAFL	Uncharacterized protein. (442 aa)
	C3Y050_BRAFL	Protein kinase domain-containing protein. (173 aa)
	C3XYJ1_BRAFL	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1011 aa)
	C3XWX5_BRAFL	Protein kinase domain-containing protein. (241 aa)
	C3XWJ7_BRAFL	PH domain-containing protein. (791 aa)
	C3XU96_BRAFL	IRS-type PTB domain-containing protein. (229 aa)
	C3ZSL6_BRAFL	Protein kinase domain-containing protein. (277 aa)
	C3ZSL5_BRAFL	Protein kinase domain-containing protein. (294 aa)
	C3ZSL1_BRAFL	Protein kinase domain-containing protein. (259 aa)
	C3ZE91_BRAFL	Uncharacterized protein. (232 aa)
	C3ZE89_BRAFL	Uncharacterized protein. (916 aa)
	C3YWW9_BRAFL	SH3 domain-containing protein. (59 aa)
	C3YW40_BRAFL	Uncharacterized protein. (756 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XU96_BRAFL	C3XWJ7_BRAFL	C3XU96	C3XWJ7	IRS-type PTB domain-containing protein.	PH domain-containing protein.	0.447
C3XU96_BRAFL	C3YA44_BRAFL	C3XU96	C3YA44	IRS-type PTB domain-containing protein.	Uncharacterized protein.	0.421
C3XWJ7_BRAFL	C3XU96_BRAFL	C3XWJ7	C3XU96	PH domain-containing protein.	IRS-type PTB domain-containing protein.	0.447
C3XWJ7_BRAFL	C3XYJ1_BRAFL	C3XWJ7	C3XYJ1	PH domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.505
C3XWJ7_BRAFL	C3Y4J7_BRAFL	C3XWJ7	C3Y4J7	PH domain-containing protein.	Uncharacterized protein.	0.836
C3XWJ7_BRAFL	C3Y6Q0_BRAFL	C3XWJ7	C3Y6Q0	PH domain-containing protein.	PH domain-containing protein.	0.447
C3XWJ7_BRAFL	C3Y918_BRAFL	C3XWJ7	C3Y918	PH domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.505
C3XWJ7_BRAFL	C3YA44_BRAFL	C3XWJ7	C3YA44	PH domain-containing protein.	Uncharacterized protein.	0.873
C3XWJ7_BRAFL	C3YMZ3_BRAFL	C3XWJ7	C3YMZ3	PH domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.505
C3XWJ7_BRAFL	C3YWW9_BRAFL	C3XWJ7	C3YWW9	PH domain-containing protein.	SH3 domain-containing protein.	0.995
C3XWX5_BRAFL	C3Y4J7_BRAFL	C3XWX5	C3Y4J7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.418
C3XWX5_BRAFL	C3YA44_BRAFL	C3XWX5	C3YA44	Protein kinase domain-containing protein.	Uncharacterized protein.	0.406
C3XWX5_BRAFL	C3YWW9_BRAFL	C3XWX5	C3YWW9	Protein kinase domain-containing protein.	SH3 domain-containing protein.	0.454
C3XYJ1_BRAFL	C3XWJ7_BRAFL	C3XYJ1	C3XWJ7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	PH domain-containing protein.	0.505
C3XYJ1_BRAFL	C3Y4J7_BRAFL	C3XYJ1	C3Y4J7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.510
C3XYJ1_BRAFL	C3Y918_BRAFL	C3XYJ1	C3Y918	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.545
C3XYJ1_BRAFL	C3YA44_BRAFL	C3XYJ1	C3YA44	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.975
C3XYJ1_BRAFL	C3YMZ3_BRAFL	C3XYJ1	C3YMZ3	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.902
C3XYJ1_BRAFL	C3YW40_BRAFL	C3XYJ1	C3YW40	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.577
C3XYJ1_BRAFL	C3YWW9_BRAFL	C3XYJ1	C3YWW9	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	SH3 domain-containing protein.	0.598