(26 nodes) Extra-nuclear estrogen signaling network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XQ95_BRAFL	Neuroblastoma RAS viral oncogene-like protein. (189 aa)
	C3XRB1_BRAFL	Uncharacterized protein. (367 aa)
	C3XSM6_BRAFL	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (347 aa)
	C3XU19_BRAFL	Uncharacterized protein. (169 aa)
	C3XY80_BRAFL	Gi alpha subunit. (354 aa)
	C3Y073_BRAFL	Importin N-terminal domain-containing protein. (1069 aa)
	C3Y5Z3_BRAFL	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (326 aa)
	C3Y7J2_BRAFL	Uncharacterized protein. (687 aa)
	C3YA44_BRAFL	Uncharacterized protein. (1022 aa)
	C3YC71_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	C3YFC1_BRAFL	Uncharacterized protein. (249 aa)
	C3YQ23_BRAFL	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (352 aa)
	C3YQ24_BRAFL	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (353 aa)
	C3YQ92_BRAFL	WD_REPEATS_REGION domain-containing protein. (247 aa)
	C3YQA4_BRAFL	WD_REPEATS_REGION domain-containing protein. (355 aa)
	C3YWE4_BRAFL	Uncharacterized protein. (307 aa)
	Wnt3	Protein kinase domain-containing protein. (318 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZBX6_BRAFL	Uncharacterized protein. (668 aa)
	C3ZMJ1_BRAFL	Uncharacterized protein. (188 aa)
	C3ZR05_BRAFL	WD_REPEATS_REGION domain-containing protein. (725 aa)
	C3ZR20_BRAFL	Uncharacterized protein. (1121 aa)
	C3ZSA7_BRAFL	WD_REPEATS_REGION domain-containing protein. (434 aa)
	C3ZSF0_BRAFL	WD_REPEATS_REGION domain-containing protein. (341 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XQ95_BRAFL	C3YA44_BRAFL	C3XQ95	C3YA44	Neuroblastoma RAS viral oncogene-like protein.	Uncharacterized protein.	0.541
C3XQ95_BRAFL	C3YC71_BRAFL	C3XQ95	C3YC71	Neuroblastoma RAS viral oncogene-like protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.489
C3XQ95_BRAFL	C3ZBX6_BRAFL	C3XQ95	C3ZBX6	Neuroblastoma RAS viral oncogene-like protein.	Uncharacterized protein.	0.426
C3XQ95_BRAFL	C3ZMJ1_BRAFL	C3XQ95	C3ZMJ1	Neuroblastoma RAS viral oncogene-like protein.	Uncharacterized protein.	0.901
C3XRB1_BRAFL	C3XSM6_BRAFL	C3XRB1	C3XSM6	Uncharacterized protein.	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.476
C3XRB1_BRAFL	C3XU19_BRAFL	C3XRB1	C3XU19	Uncharacterized protein.	Uncharacterized protein.	0.601
C3XRB1_BRAFL	C3Y5Z3_BRAFL	C3XRB1	C3Y5Z3	Uncharacterized protein.	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.476
C3XRB1_BRAFL	C3YA44_BRAFL	C3XRB1	C3YA44	Uncharacterized protein.	Uncharacterized protein.	0.670
C3XRB1_BRAFL	C3YQ23_BRAFL	C3XRB1	C3YQ23	Uncharacterized protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.476
C3XRB1_BRAFL	C3YQ24_BRAFL	C3XRB1	C3YQ24	Uncharacterized protein.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.476
C3XRB1_BRAFL	C3YQ92_BRAFL	C3XRB1	C3YQ92	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.441
C3XRB1_BRAFL	C3YQA4_BRAFL	C3XRB1	C3YQA4	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.441
C3XRB1_BRAFL	C3Z851_BRAFL	C3XRB1	C3Z851	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.587
C3XRB1_BRAFL	C3ZR05_BRAFL	C3XRB1	C3ZR05	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.719
C3XRB1_BRAFL	C3ZSF0_BRAFL	C3XRB1	C3ZSF0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.460
C3XSM6_BRAFL	C3XRB1_BRAFL	C3XSM6	C3XRB1	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.476
C3XSM6_BRAFL	C3YQ24_BRAFL	C3XSM6	C3YQ24	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.903
C3XU19_BRAFL	C3XRB1_BRAFL	C3XU19	C3XRB1	Uncharacterized protein.	Uncharacterized protein.	0.601
C3XY80_BRAFL	C3YFC1_BRAFL	C3XY80	C3YFC1	Gi alpha subunit.	Uncharacterized protein.	0.545
C3XY80_BRAFL	C3YQ92_BRAFL	C3XY80	C3YQ92	Gi alpha subunit.	WD_REPEATS_REGION domain-containing protein.	0.862