(70 nodes) Iron uptake and transport network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XPJ9_BRAFL	MFS domain-containing protein. (442 aa)
	C3XPV8_BRAFL	MFS domain-containing protein. (467 aa)
	C3XQ25_BRAFL	MFS domain-containing protein. (476 aa)
	C3XQ97_BRAFL	Uncharacterized protein. (556 aa)
	C3XSJ8_BRAFL	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (122 aa)
	C3XW43_BRAFL	Uncharacterized protein. (413 aa)
	C3XW91_BRAFL	F420_oxidored domain-containing protein. (594 aa)
	C3XY04_BRAFL	Uncharacterized protein. (354 aa)
	C3XZ86_BRAFL	Uncharacterized protein. (250 aa)
	C3XZE0_BRAFL	Uncharacterized protein. (615 aa)
	C3Y000_BRAFL	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family. (206 aa)
	C3Y2C9_BRAFL	Uncharacterized protein. (609 aa)
	C3Y2H6_BRAFL	Uncharacterized protein. (226 aa)
	C3Y2V7_BRAFL	Amidohydro-rel domain-containing protein. (283 aa)
	C3Y3M7_BRAFL	Uncharacterized protein. (447 aa)
	C3Y3N5_BRAFL	Uncharacterized protein. (459 aa)
	C3Y468_BRAFL	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (508 aa)
	C3Y4G3_BRAFL	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (609 aa)
	C3Y4G4_BRAFL	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (618 aa)
	C3Y6H7_BRAFL	Uncharacterized protein. (326 aa)
	C3Y819_BRAFL	Uncharacterized protein. (488 aa)
	C3YAP5_BRAFL	Uncharacterized protein. (592 aa)
	C3YAP7_BRAFL	Uncharacterized protein. (431 aa)
	C3YAU7_BRAFL	Uncharacterized protein. (491 aa)
	C3YB84_BRAFL	Uncharacterized protein. (304 aa)
	C3YB87_BRAFL	CULLIN_2 domain-containing protein; Belongs to the cullin family. (771 aa)
	C3YEI3_BRAFL	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa)
	C3YGI7_BRAFL	Uncharacterized protein. (440 aa)
	C3YIJ4_BRAFL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (174 aa)
	C3YIN2_BRAFL	NUC173 domain-containing protein. (1285 aa)
	C3YJC0_BRAFL	Metallophos domain-containing protein. (340 aa)
	C3YL90_BRAFL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (179 aa)
	C3YLM6_BRAFL	F-box domain-containing protein. (645 aa)
	C3YMJ6_BRAFL	Uncharacterized protein. (602 aa)
	C3YMJ7_BRAFL	Uncharacterized protein. (414 aa)
	C3YP57_BRAFL	Uncharacterized protein; Belongs to the SKP1 family. (196 aa)
	C3YTV2_BRAFL	TIP120 domain-containing protein. (1239 aa)
	C3YVK6_BRAFL	Uncharacterized protein. (455 aa)
	C3YWC1_BRAFL	Uncharacterized protein. (528 aa)
	C3YXB2_BRAFL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (172 aa)
	C3YZ96_BRAFL	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (159 aa)
	C3YZL4_BRAFL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (139 aa)
	C3YZR5_BRAFL	Uncharacterized protein. (600 aa)
	C3Z1V9_BRAFL	Uncharacterized protein. (405 aa)
	C3Z2G0_BRAFL	Uncharacterized protein. (488 aa)
	C3Z315_BRAFL	MFS domain-containing protein. (263 aa)
	C3Z316_BRAFL	Uncharacterized protein. (374 aa)
	C3Z324_BRAFL	MFS domain-containing protein. (448 aa)
	C3Z325_BRAFL	MFS domain-containing protein. (425 aa)
	C3Z577_BRAFL	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (117 aa)
	C3Z624_BRAFL	ABC2_membrane domain-containing protein. (390 aa)
	C3Z627_BRAFL	ABC transporter domain-containing protein. (629 aa)
	C3Z8M0_BRAFL	Cytochrome b561 domain-containing protein. (257 aa)
	C3Z8Z4_BRAFL	Uncharacterized protein. (468 aa)
	C3ZA17_BRAFL	MFS domain-containing protein. (478 aa)
	C3ZBV8_BRAFL	Metallophos domain-containing protein. (376 aa)
	C3ZCW5_BRAFL	MFS domain-containing protein. (468 aa)
	C3ZEB1_BRAFL	Uncharacterized protein; Belongs to the multicopper oxidase family. (1194 aa)
	C3ZEB2_BRAFL	Uncharacterized protein; Belongs to the multicopper oxidase family. (1057 aa)
	C3ZED4_BRAFL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (173 aa)
	Arx1	ABC transporter domain-containing protein. (110 aa)
	C3ZH23_BRAFL	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (838 aa)
	C3ZJJ5_BRAFL	Uncharacterized protein; Belongs to the aconitase/IPM isomerase family. (937 aa)
	C3ZKC2_BRAFL	Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Belongs to the ferritin family. (234 aa)
	C3ZN84_BRAFL	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (462 aa)
	C3ZQD9_BRAFL	MFS domain-containing protein. (448 aa)
	C3ZRD1_BRAFL	RRM domain-containing protein. (164 aa)
	C3ZRD2_BRAFL	RRM domain-containing protein. (204 aa)
	C3ZRF6_BRAFL	Ubiquitin-like domain-containing protein. (77 aa)
	C3ZSV7_BRAFL	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (394 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XSJ8_BRAFL	C3XZ86_BRAFL	C3XSJ8	C3XZ86	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
C3XSJ8_BRAFL	C3XZE0_BRAFL	C3XSJ8	C3XZE0	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
C3XSJ8_BRAFL	C3Y000_BRAFL	C3XSJ8	C3Y000	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.999
C3XSJ8_BRAFL	C3Y2H6_BRAFL	C3XSJ8	C3Y2H6	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.999
C3XSJ8_BRAFL	C3Y2V7_BRAFL	C3XSJ8	C3Y2V7	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Amidohydro-rel domain-containing protein.	0.987
C3XSJ8_BRAFL	C3Y468_BRAFL	C3XSJ8	C3Y468	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
C3XSJ8_BRAFL	C3YAU7_BRAFL	C3XSJ8	C3YAU7	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Uncharacterized protein.	0.987
C3XSJ8_BRAFL	C3YEI3_BRAFL	C3XSJ8	C3YEI3	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family.	0.999
C3XSJ8_BRAFL	C3YZ96_BRAFL	C3XSJ8	C3YZ96	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
C3XSJ8_BRAFL	C3Z577_BRAFL	C3XSJ8	C3Z577	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
C3XSJ8_BRAFL	C3ZH23_BRAFL	C3XSJ8	C3ZH23	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
C3XSJ8_BRAFL	C3ZN84_BRAFL	C3XSJ8	C3ZN84	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.	0.999
C3XSJ8_BRAFL	C3ZSV7_BRAFL	C3XSJ8	C3ZSV7	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
C3XZ86_BRAFL	C3XSJ8_BRAFL	C3XZ86	C3XSJ8	Uncharacterized protein.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.999
C3XZ86_BRAFL	C3XZE0_BRAFL	C3XZ86	C3XZE0	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XZ86_BRAFL	C3Y000_BRAFL	C3XZ86	C3Y000	Uncharacterized protein.	Uncharacterized protein; Belongs to the V-ATPase proteolipid subunit family.	0.999
C3XZ86_BRAFL	C3Y2H6_BRAFL	C3XZ86	C3Y2H6	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XZ86_BRAFL	C3Y2V7_BRAFL	C3XZ86	C3Y2V7	Uncharacterized protein.	Amidohydro-rel domain-containing protein.	0.982
C3XZ86_BRAFL	C3Y468_BRAFL	C3XZ86	C3Y468	Uncharacterized protein.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.999
C3XZ86_BRAFL	C3YAU7_BRAFL	C3XZ86	C3YAU7	Uncharacterized protein.	Uncharacterized protein.	0.998