(29 nodes) Nucleotide excision repair network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	C3XXK6_BRAFL	AAA domain-containing protein. (356 aa)
	C3XXN0_BRAFL	RING-type domain-containing protein. (111 aa)
	C3XY57_BRAFL	WD_REPEATS_REGION domain-containing protein. (397 aa)
	C3XYH7_BRAFL	WD_REPEATS_REGION domain-containing protein. (358 aa)
	C3Y0G6_BRAFL	RING-type domain-containing protein. (906 aa)
	C3Y0H1_BRAFL	Helicase ATP-binding domain-containing protein. (763 aa)
	C3Y693_BRAFL	Uncharacterized protein. (551 aa)
	C3Y7R7_BRAFL	XPGI domain-containing protein. (162 aa)
	C3Y9F3_BRAFL	Uncharacterized protein. (449 aa)
	C3Y9V2_BRAFL	CBFD_NFYB_HMF domain-containing protein. (115 aa)
	C3YBM8_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (218 aa)
	C3YBY7_BRAFL	Uncharacterized protein. (798 aa)
	C3YD69_BRAFL	Uncharacterized protein. (573 aa)
	C3YDK8_BRAFL	AAA domain-containing protein. (362 aa)
	C3YEL6_BRAFL	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (579 aa)
	C3YN18_BRAFL	General transcription factor IIH subunit. (396 aa)
	C3YQX9_BRAFL	XPA_C domain-containing protein. (259 aa)
	C3YTK8_BRAFL	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (457 aa)
	C3YUN6_BRAFL	Uncharacterized protein. (118 aa)
	C3Z899_BRAFL	AAA domain-containing protein. (364 aa)
	C3ZD95_BRAFL	Uncharacterized protein. (499 aa)
	C3ZF52_BRAFL	CULLIN_2 domain-containing protein; Belongs to the cullin family. (822 aa)
	C3ZHV8_BRAFL	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (265 aa)
	C3ZL26_BRAFL	AAA domain-containing protein. (329 aa)
	C3ZMJ6_BRAFL	CPSF_A domain-containing protein. (1152 aa)
	C3ZNW9_BRAFL	ERCC4 domain-containing protein. (515 aa)
	C3ZRF2_BRAFL	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	C3ZWY4_BRAFL	CBFD_NFYB_HMF domain-containing protein. (153 aa)
	C4A0W1_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (326 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XXK6_BRAFL	C3XXN0_BRAFL	C3XXK6	C3XXN0	AAA domain-containing protein.	RING-type domain-containing protein.	0.704
C3XXK6_BRAFL	C3Y0H1_BRAFL	C3XXK6	C3Y0H1	AAA domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.418
C3XXK6_BRAFL	C3Y693_BRAFL	C3XXK6	C3Y693	AAA domain-containing protein.	Uncharacterized protein.	0.520
C3XXK6_BRAFL	C3Y7R7_BRAFL	C3XXK6	C3Y7R7	AAA domain-containing protein.	XPGI domain-containing protein.	0.413
C3XXK6_BRAFL	C3Y9F3_BRAFL	C3XXK6	C3Y9F3	AAA domain-containing protein.	Uncharacterized protein.	0.853
C3XXK6_BRAFL	C3Y9V2_BRAFL	C3XXK6	C3Y9V2	AAA domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.769
C3XXK6_BRAFL	C3YBY7_BRAFL	C3XXK6	C3YBY7	AAA domain-containing protein.	Uncharacterized protein.	0.577
C3XXK6_BRAFL	C3YDK8_BRAFL	C3XXK6	C3YDK8	AAA domain-containing protein.	AAA domain-containing protein.	0.999
C3XXK6_BRAFL	C3YEL6_BRAFL	C3XXK6	C3YEL6	AAA domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.815
C3XXK6_BRAFL	C3YN18_BRAFL	C3XXK6	C3YN18	AAA domain-containing protein.	General transcription factor IIH subunit.	0.548
C3XXK6_BRAFL	C3YQX9_BRAFL	C3XXK6	C3YQX9	AAA domain-containing protein.	XPA_C domain-containing protein.	0.556
C3XXK6_BRAFL	C3YUN6_BRAFL	C3XXK6	C3YUN6	AAA domain-containing protein.	Uncharacterized protein.	0.749
C3XXK6_BRAFL	C3Z899_BRAFL	C3XXK6	C3Z899	AAA domain-containing protein.	AAA domain-containing protein.	0.999
C3XXK6_BRAFL	C3ZD95_BRAFL	C3XXK6	C3ZD95	AAA domain-containing protein.	Uncharacterized protein.	0.419
C3XXK6_BRAFL	C3ZF52_BRAFL	C3XXK6	C3ZF52	AAA domain-containing protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.687
C3XXK6_BRAFL	C3ZHV8_BRAFL	C3XXK6	C3ZHV8	AAA domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.784
C3XXK6_BRAFL	C3ZL26_BRAFL	C3XXK6	C3ZL26	AAA domain-containing protein.	AAA domain-containing protein.	0.999
C3XXK6_BRAFL	C3ZMJ6_BRAFL	C3XXK6	C3ZMJ6	AAA domain-containing protein.	CPSF_A domain-containing protein.	0.725
C3XXK6_BRAFL	C3ZNW9_BRAFL	C3XXK6	C3ZNW9	AAA domain-containing protein.	ERCC4 domain-containing protein.	0.639
C3XXK6_BRAFL	C3ZRF2_BRAFL	C3XXK6	C3ZRF2	AAA domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.999