(26 nodes) Fanconi anemia pathway network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XPV5_BRAFL	Uncharacterized protein. (268 aa)
	C3XX89_BRAFL	Uncharacterized protein. (781 aa)
	C3XZ04_BRAFL	Uncharacterized protein. (358 aa)
	C3Y3L8_BRAFL	POLAc domain-containing protein. (196 aa)
	C3Y458_BRAFL	DNA_mis_repair domain-containing protein. (717 aa)
	C3YBI7_BRAFL	UmuC domain-containing protein. (493 aa)
	C3YI31_BRAFL	DUF1767 domain-containing protein. (184 aa)
	C3YI96_BRAFL	DNA polymerase. (813 aa)
	C3YIZ2_BRAFL	Uncharacterized protein. (915 aa)
	C3YKN6_BRAFL	WD_REPEATS_REGION domain-containing protein. (665 aa)
	C3YKR1_BRAFL	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (666 aa)
	C3YR36_BRAFL	Uncharacterized protein. (290 aa)
	C3YR39_BRAFL	Uncharacterized protein. (291 aa)
	C3YR42_BRAFL	Uncharacterized protein. (300 aa)
	C3YUN6_BRAFL	Uncharacterized protein. (118 aa)
	C3YW39_BRAFL	Uncharacterized protein. (2614 aa)
	C3YZM5_BRAFL	Uncharacterized protein. (453 aa)
	C3Z1Q7_BRAFL	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (858 aa)
	C3Z3L2_BRAFL	UmuC domain-containing protein. (354 aa)
	C3Z419_BRAFL	GIY-YIG domain-containing protein. (155 aa)
	C3Z6W7_BRAFL	ERCC4 domain-containing protein. (598 aa)
	C3Z742_BRAFL	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (684 aa)
	C3Z7U0_BRAFL	DNA_mis_repair domain-containing protein. (429 aa)
	C3Z943_BRAFL	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (104 aa)
	C3ZHV8_BRAFL	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (265 aa)
	C3ZNW9_BRAFL	ERCC4 domain-containing protein. (515 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XPV5_BRAFL	C3XX89_BRAFL	C3XPV5	C3XX89	Uncharacterized protein.	Uncharacterized protein.	0.800
C3XPV5_BRAFL	C3XZ04_BRAFL	C3XPV5	C3XZ04	Uncharacterized protein.	Uncharacterized protein.	0.873
C3XPV5_BRAFL	C3YIZ2_BRAFL	C3XPV5	C3YIZ2	Uncharacterized protein.	Uncharacterized protein.	0.900
C3XPV5_BRAFL	C3Z943_BRAFL	C3XPV5	C3Z943	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.802
C3XX89_BRAFL	C3XPV5_BRAFL	C3XX89	C3XPV5	Uncharacterized protein.	Uncharacterized protein.	0.800
C3XX89_BRAFL	C3XZ04_BRAFL	C3XX89	C3XZ04	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XX89_BRAFL	C3Y3L8_BRAFL	C3XX89	C3Y3L8	Uncharacterized protein.	POLAc domain-containing protein.	0.439
C3XX89_BRAFL	C3YIZ2_BRAFL	C3XX89	C3YIZ2	Uncharacterized protein.	Uncharacterized protein.	0.980
C3XX89_BRAFL	C3YKN6_BRAFL	C3XX89	C3YKN6	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.587
C3XX89_BRAFL	C3YR36_BRAFL	C3XX89	C3YR36	Uncharacterized protein.	Uncharacterized protein.	0.800
C3XX89_BRAFL	C3YR39_BRAFL	C3XX89	C3YR39	Uncharacterized protein.	Uncharacterized protein.	0.800
C3XX89_BRAFL	C3YR42_BRAFL	C3XX89	C3YR42	Uncharacterized protein.	Uncharacterized protein.	0.800
C3XX89_BRAFL	C3Z419_BRAFL	C3XX89	C3Z419	Uncharacterized protein.	GIY-YIG domain-containing protein.	0.482
C3XX89_BRAFL	C3Z6W7_BRAFL	C3XX89	C3Z6W7	Uncharacterized protein.	ERCC4 domain-containing protein.	0.503
C3XX89_BRAFL	C3Z943_BRAFL	C3XX89	C3Z943	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.992
C3XX89_BRAFL	C3ZNW9_BRAFL	C3XX89	C3ZNW9	Uncharacterized protein.	ERCC4 domain-containing protein.	0.809
C3XZ04_BRAFL	C3XPV5_BRAFL	C3XZ04	C3XPV5	Uncharacterized protein.	Uncharacterized protein.	0.873
C3XZ04_BRAFL	C3XX89_BRAFL	C3XZ04	C3XX89	Uncharacterized protein.	Uncharacterized protein.	0.999
C3XZ04_BRAFL	C3Y3L8_BRAFL	C3XZ04	C3Y3L8	Uncharacterized protein.	POLAc domain-containing protein.	0.481
C3XZ04_BRAFL	C3YIZ2_BRAFL	C3XZ04	C3YIZ2	Uncharacterized protein.	Uncharacterized protein.	0.995