(55 nodes) FoxO signaling pathway network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XQ95_BRAFL	Neuroblastoma RAS viral oncogene-like protein. (189 aa)
	C3XQP6_BRAFL	Mitogen-activated protein kinase. (349 aa)
	C3XSM6_BRAFL	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (347 aa)
	C3XSS3_BRAFL	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (373 aa)
	C3XYJ1_BRAFL	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1011 aa)
	C3XZI5_BRAFL	Uncharacterized protein. (1222 aa)
	C3Y0G7_BRAFL	Fork-head domain-containing protein. (402 aa)
	C3Y1P3_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (411 aa)
	C3Y282_BRAFL	WH1 domain-containing protein. (561 aa)
	C3Y291_BRAFL	Non-specific serine/threonine protein kinase. (296 aa)
	C3Y3U7_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (376 aa)
	C3Y4M5_BRAFL	SET domain-containing protein. (363 aa)
	C3Y7C4_BRAFL	Catalase domain-containing protein. (275 aa)
	C3Y7L6_BRAFL	SWIB domain-containing protein. (400 aa)
	C3Y812_BRAFL	Uncharacterized protein. (691 aa)
	C3Y8L2_BRAFL	Uncharacterized protein. (117 aa)
	C3YBW1_BRAFL	Uncharacterized protein. (304 aa)
	C3YC71_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (474 aa)
	C3YG83_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (437 aa)
	C3YI11_BRAFL	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
	C3YI59_BRAFL	Fork-head domain-containing protein. (157 aa)
	C3YIU5_BRAFL	Uncharacterized protein. (607 aa)
	C3YKX2_BRAFL	Deacetylase sirtuin-type domain-containing protein. (312 aa)
	C3YMZ3_BRAFL	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	C3YNL4_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein. (322 aa)
	C3YP14_BRAFL	Mitogen-activated protein kinase. (209 aa)
	C3YQ07_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (459 aa)
	C3YQ24_BRAFL	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (353 aa)
	C3YS84_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (293 aa)
	C3YUU6_BRAFL	Uncharacterized protein. (232 aa)
	C3YWJ5_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (118 aa)
	C3YWJ6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (96 aa)
	C3YWW9_BRAFL	SH3 domain-containing protein. (59 aa)
	C3Z304_BRAFL	Protein kinase domain-containing protein. (107 aa)
	C3Z484_BRAFL	Mitogen-activated protein kinase. (385 aa)
	C3Z933_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (459 aa)
	C3ZAU8_BRAFL	Uncharacterized protein. (623 aa)
	C3ZDQ4_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (285 aa)
	C3ZDQ6_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (95 aa)
	C3ZDV8_BRAFL	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (313 aa)
	C3ZE05_BRAFL	TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (113 aa)
	C3ZGJ5_BRAFL	Uncharacterized protein. (150 aa)
	C3ZGZ3_BRAFL	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (501 aa)
	C3ZI99_BRAFL	Uncharacterized protein. (117 aa)
	C3ZJI8_BRAFL	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (86 aa)
	C3ZM82_BRAFL	G_PROTEIN_RECEP_F3_4 domain-containing protein. (840 aa)
	C3ZMJ1_BRAFL	Uncharacterized protein. (188 aa)
	C3ZNJ6_BRAFL	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa)
	C3ZPX7_BRAFL	Uncharacterized protein; Belongs to the peptidase C19 family. (1046 aa)
	C3ZSX0_BRAFL	CYCLIN domain-containing protein; Belongs to the cyclin family. (317 aa)
	C3ZU02_BRAFL	Uncharacterized protein. (1203 aa)
	C3ZUG6_BRAFL	Uncharacterized protein. (3563 aa)
	C3ZXG1_BRAFL	Uncharacterized protein. (122 aa)
	C3ZZX0_BRAFL	Protein kinase domain-containing protein. (287 aa)
	C4A0B6_BRAFL	Tyrosine-protein kinase receptor. (1336 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XQ95_BRAFL	C3XYJ1_BRAFL	C3XQ95	C3XYJ1	Neuroblastoma RAS viral oncogene-like protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.552
C3XQ95_BRAFL	C3XZI5_BRAFL	C3XQ95	C3XZI5	Neuroblastoma RAS viral oncogene-like protein.	Uncharacterized protein.	0.971
C3XQ95_BRAFL	C3YC71_BRAFL	C3XQ95	C3YC71	Neuroblastoma RAS viral oncogene-like protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.489
C3XQ95_BRAFL	C3YMZ3_BRAFL	C3XQ95	C3YMZ3	Neuroblastoma RAS viral oncogene-like protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.552
C3XQ95_BRAFL	C3YQ07_BRAFL	C3XQ95	C3YQ07	Neuroblastoma RAS viral oncogene-like protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.541
C3XQ95_BRAFL	C3YWW9_BRAFL	C3XQ95	C3YWW9	Neuroblastoma RAS viral oncogene-like protein.	SH3 domain-containing protein.	0.659
C3XQ95_BRAFL	C3ZMJ1_BRAFL	C3XQ95	C3ZMJ1	Neuroblastoma RAS viral oncogene-like protein.	Uncharacterized protein.	0.901
C3XQP6_BRAFL	C3Y291_BRAFL	C3XQP6	C3Y291	Mitogen-activated protein kinase.	Non-specific serine/threonine protein kinase.	0.493
C3XQP6_BRAFL	C3YC71_BRAFL	C3XQP6	C3YC71	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.472
C3XQP6_BRAFL	C3YI59_BRAFL	C3XQP6	C3YI59	Mitogen-activated protein kinase.	Fork-head domain-containing protein.	0.918
C3XQP6_BRAFL	C3YQ07_BRAFL	C3XQP6	C3YQ07	Mitogen-activated protein kinase.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.635
C3XQP6_BRAFL	C3YUU6_BRAFL	C3XQP6	C3YUU6	Mitogen-activated protein kinase.	Uncharacterized protein.	0.546
C3XQP6_BRAFL	C3Z304_BRAFL	C3XQP6	C3Z304	Mitogen-activated protein kinase.	Protein kinase domain-containing protein.	0.900
C3XQP6_BRAFL	C3ZNJ6_BRAFL	C3XQP6	C3ZNJ6	Mitogen-activated protein kinase.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.455
C3XSM6_BRAFL	C3YI59_BRAFL	C3XSM6	C3YI59	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Fork-head domain-containing protein.	0.910
C3XSM6_BRAFL	C3YQ24_BRAFL	C3XSM6	C3YQ24	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.903
C3XSM6_BRAFL	C3ZUG6_BRAFL	C3XSM6	C3ZUG6	Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Uncharacterized protein.	0.414
C3XSS3_BRAFL	C3YWW9_BRAFL	C3XSS3	C3YWW9	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	SH3 domain-containing protein.	0.418
C3XYJ1_BRAFL	C3XQ95_BRAFL	C3XYJ1	C3XQ95	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Neuroblastoma RAS viral oncogene-like protein.	0.552
C3XYJ1_BRAFL	C3XZI5_BRAFL	C3XYJ1	C3XZI5	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.611