(96 nodes) Endocytosis network (Branchiostoma floridae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C3XS36_BRAFL	Uncharacterized protein; Belongs to the heat shock protein 70 family. (638 aa)
	C3XSA1_BRAFL	Folate_rec domain-containing protein. (278 aa)
	C3XSA3_BRAFL	Uncharacterized protein. (213 aa)
	C3XSS2_BRAFL	PX domain-containing protein. (402 aa)
	C3XSS3_BRAFL	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (373 aa)
	C3XT97_BRAFL	WASH_WAHD domain-containing protein. (297 aa)
	C3XTH3_BRAFL	Uncharacterized protein. (217 aa)
	C3XTU6_BRAFL	Uncharacterized protein. (211 aa)
	C3XUB7_BRAFL	Uncharacterized protein. (201 aa)
	C3XUF6_BRAFL	Folate_rec domain-containing protein. (190 aa)
	C3XUQ0_BRAFL	PX domain-containing protein. (164 aa)
	C3XVP4_BRAFL	VPS37 C-terminal domain-containing protein. (169 aa)
	C3XW59_BRAFL	VPS37 C-terminal domain-containing protein. (287 aa)
	C3XW83_BRAFL	MIT domain-containing protein. (653 aa)
	C3XXX7_BRAFL	PID domain-containing protein. (128 aa)
	C3XY23_BRAFL	Protein kinase domain-containing protein. (170 aa)
	C3Y059_BRAFL	SEC7 domain-containing protein. (148 aa)
	C3Y074_BRAFL	Sorting nexin; Involved in several stages of intracellular trafficking. (415 aa)
	C3Y0S6_BRAFL	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (183 aa)
	C3Y134_BRAFL	BRO1 domain-containing protein. (874 aa)
	C3Y181_BRAFL	Folate_rec domain-containing protein. (242 aa)
	C3Y1H4_BRAFL	Uncharacterized protein. (1156 aa)
	C3Y1S4_BRAFL	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (571 aa)
	C3Y1T3_BRAFL	AB hydrolase-1 domain-containing protein. (311 aa)
	C3Y295_BRAFL	SEC7 domain-containing protein. (753 aa)
	C3Y2F0_BRAFL	Uncharacterized protein. (745 aa)
	C3Y2Y1_BRAFL	Uncharacterized protein. (483 aa)
	C3Y3K6_BRAFL	GLUE N-terminal domain-containing protein. (392 aa)
	C3Y405_BRAFL	Protein kinase domain-containing protein. (163 aa)
	C3Y4G6_BRAFL	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (293 aa)
	C3Y5N3_BRAFL	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (525 aa)
	C3Y6N0_BRAFL	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (209 aa)
	C3Y7L6_BRAFL	SWIB domain-containing protein. (400 aa)
	C3Y8Z8_BRAFL	Uncharacterized protein. (396 aa)
	C3Y9Z0_BRAFL	FYVE-type domain-containing protein. (1858 aa)
	C3YBE1_BRAFL	Uncharacterized protein. (502 aa)
	C3YDG6_BRAFL	G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
	C3YDX8_BRAFL	Uncharacterized protein. (217 aa)
	C3YEH0_BRAFL	Uncharacterized protein; Belongs to the AAA ATPase family. (440 aa)
	C3YFS3_BRAFL	Uncharacterized protein. (188 aa)
	C3YGH7_BRAFL	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (779 aa)
	C3YHW0_BRAFL	BAR domain-containing protein. (202 aa)
	C3YHW5_BRAFL	Uncharacterized protein. (222 aa)
	C3YIG6_BRAFL	Protein kinase domain-containing protein. (270 aa)
	C3YIV6_BRAFL	Uncharacterized protein. (222 aa)
	C3YJ83_BRAFL	RING-type domain-containing protein. (180 aa)
	C3YL39_BRAFL	Uncharacterized protein; Belongs to the heat shock protein 70 family. (660 aa)
	C3YPL0_BRAFL	Uncharacterized protein. (519 aa)
	C3YPL9_BRAFL	Protein kinase domain-containing protein. (290 aa)
	C3YPR1_BRAFL	PX domain-containing protein. (497 aa)
	C3YPV2_BRAFL	Uncharacterized protein. (170 aa)
	C3YUG4_BRAFL	Uncharacterized protein. (1144 aa)
	C3YVW2_BRAFL	Uncharacterized protein. (603 aa)
	C3YW93_BRAFL	ENTH domain-containing protein. (183 aa)
	C3YWT1_BRAFL	Uncharacterized protein. (185 aa)
	C3YXI8_BRAFL	Uncharacterized protein. (289 aa)
	C3YYU3_BRAFL	Uncharacterized protein. (173 aa)
	C3YZN7_BRAFL	Folate_rec domain-containing protein. (203 aa)
	C3YZV8_BRAFL	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
	C3Z3B1_BRAFL	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	C3Z3J8_BRAFL	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	C3Z404_BRAFL	Uncharacterized protein. (211 aa)
	C3Z473_BRAFL	Uncharacterized protein. (207 aa)
	C3Z4W4_BRAFL	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
	C3Z641_BRAFL	Uncharacterized protein. (66 aa)
	C3Z655_BRAFL	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (159 aa)
	C3Z6I2_BRAFL	Uncharacterized protein. (227 aa)
	C3Z6I7_BRAFL	UEV domain-containing protein. (115 aa)
	C3Z6W8_BRAFL	Uncharacterized protein. (248 aa)
	C3Z7U6_BRAFL	HECT domain-containing protein. (341 aa)
	C3Z851_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (135 aa)
	C3Z904_BRAFL	Uncharacterized protein. (205 aa)
	C3Z974_BRAFL	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (163 aa)
	C3ZAR1_BRAFL	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (286 aa)
	C3ZB87_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZB88_BRAFL	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (138 aa)
	C3ZBZ7_BRAFL	Uncharacterized protein. (273 aa)
	C3ZC01_BRAFL	Uncharacterized protein. (164 aa)
	C3ZCF7_BRAFL	Uncharacterized protein. (199 aa)
	C3ZCR6_BRAFL	Uncharacterized protein. (185 aa)
	C3ZD31_BRAFL	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (218 aa)
	C3ZDM9_BRAFL	Uncharacterized protein. (276 aa)
	C3ZF04_BRAFL	Arf-GAP domain-containing protein. (479 aa)
	C3ZFF9_BRAFL	Uncharacterized protein. (170 aa)
	C3ZHV5_BRAFL	Rabaptin domain-containing protein. (163 aa)
	C3ZIB9_BRAFL	Uncharacterized protein. (191 aa)
	C3ZJE4_BRAFL	Uncharacterized protein. (209 aa)
	C3ZLV4_BRAFL	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (351 aa)
	C3ZMD5_BRAFL	Uncharacterized protein. (2276 aa)
	C3ZNR9_BRAFL	Uncharacterized protein. (359 aa)
	C3ZRX8_BRAFL	Uncharacterized protein. (203 aa)
	C3ZS91_BRAFL	Uncharacterized protein. (159 aa)
	C3ZSI1_BRAFL	Uncharacterized protein. (317 aa)
	C3ZTX9_BRAFL	Uncharacterized protein. (198 aa)
	C3ZUX5_BRAFL	UEV domain-containing protein. (143 aa)
	C3ZXG3_BRAFL	Arf-GAP domain-containing protein. (128 aa)

Your Current Organism:

Branchiostoma floridae

NCBI taxonomy Id: 7739
Other names: Amphioxus floridae, B. floridae, Florida lancelet

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C3XS36_BRAFL	C3YL39_BRAFL	C3XS36	C3YL39	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.901
C3XS36_BRAFL	C3YZV8_BRAFL	C3XS36	C3YZV8	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.497
C3XS36_BRAFL	C3Z4W4_BRAFL	C3XS36	C3Z4W4	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.440
C3XSA3_BRAFL	C3XSS3_BRAFL	C3XSA3	C3XSS3	Uncharacterized protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.960
C3XSA3_BRAFL	C3YFS3_BRAFL	C3XSA3	C3YFS3	Uncharacterized protein.	Uncharacterized protein.	0.903
C3XSA3_BRAFL	C3Z404_BRAFL	C3XSA3	C3Z404	Uncharacterized protein.	Uncharacterized protein.	0.909
C3XSA3_BRAFL	C3Z7U6_BRAFL	C3XSA3	C3Z7U6	Uncharacterized protein.	HECT domain-containing protein.	0.631
C3XSA3_BRAFL	C3Z851_BRAFL	C3XSA3	C3Z851	Uncharacterized protein.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.424
C3XSA3_BRAFL	C3Z904_BRAFL	C3XSA3	C3Z904	Uncharacterized protein.	Uncharacterized protein.	0.427
C3XSA3_BRAFL	C3ZBZ7_BRAFL	C3XSA3	C3ZBZ7	Uncharacterized protein.	Uncharacterized protein.	0.654
C3XSA3_BRAFL	C3ZIB9_BRAFL	C3XSA3	C3ZIB9	Uncharacterized protein.	Uncharacterized protein.	0.605
C3XSA3_BRAFL	C3ZTX9_BRAFL	C3XSA3	C3ZTX9	Uncharacterized protein.	Uncharacterized protein.	0.524
C3XSS2_BRAFL	C3XUQ0_BRAFL	C3XSS2	C3XUQ0	PX domain-containing protein.	PX domain-containing protein.	0.587
C3XSS2_BRAFL	C3Y074_BRAFL	C3XSS2	C3Y074	PX domain-containing protein.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.712
C3XSS2_BRAFL	C3YGH7_BRAFL	C3XSS2	C3YGH7	PX domain-containing protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.751
C3XSS2_BRAFL	C3YPR1_BRAFL	C3XSS2	C3YPR1	PX domain-containing protein.	PX domain-containing protein.	0.603
C3XSS2_BRAFL	C3YZV8_BRAFL	C3XSS2	C3YZV8	PX domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.422
C3XSS2_BRAFL	C3ZMD5_BRAFL	C3XSS2	C3ZMD5	PX domain-containing protein.	Uncharacterized protein.	0.476
C3XSS2_BRAFL	C3ZSI1_BRAFL	C3XSS2	C3ZSI1	PX domain-containing protein.	Uncharacterized protein.	0.716
C3XSS3_BRAFL	C3XSA3_BRAFL	C3XSS3	C3XSA3	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Uncharacterized protein.	0.960