Your Input: | |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (302 aa) |
| | Xaut_0023 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: sme:SMc00719 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (178 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (448 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (357 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (232 aa) |
| | Xaut_0071 | PFAM: Pyridoxal-dependent decarboxylase; KEGG: mlo:mll0712 aromatic amino acid decarboxylase. (474 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (300 aa) |
| | Xaut_0393 | PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: nha:Nham_0673 prephenate dehydrogenase. (313 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: mes:Meso_3084 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (392 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (290 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (524 aa) |
| | Xaut_0476 | TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mlo:mll3029 glutamate synthase (NADPH) small chain. (473 aa) |
| | Xaut_0477 | PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bov:BOV_A0049 glutamate synthase, large subunit. (1567 aa) |
| | Xaut_0649 | KEGG: acr:Acry_1431 esterase/lipase-like protein. (284 aa) |
| | Xaut_0650 | PFAM: amidohydrolase; Amidohydrolase 3; KEGG: bja:blr3349 dihydroorotase. (425 aa) |
| | Xaut_0887 | PFAM: glutamine synthetase catalytic region; KEGG: mlo:mll5148 probable glutamine synthetase. (459 aa) |
| | Xaut_0923 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: gbe:GbCGDNIH1_1826 aminomethyltransferase; Belongs to the GcvT family. (379 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (456 aa) |
| | Xaut_1141 | Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: sme:SMb20745 putative glutatmine synthetase II protein. (344 aa) |
| | glsA | PFAM: glutaminase; KEGG: bja:bll4798 putative glutaminase; Belongs to the glutaminase family. (331 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: bov:BOV_0314 putative acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (402 aa) |
| | arcB | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (309 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (430 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: rpb:RPB_4142 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (411 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (369 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (160 aa) |
| | fhs | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: pde:Pden_1580 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (565 aa) |
| | purD | TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; KEGG: mlo:mlr7447 phosphoribosylamine-glycine ligase; Belongs to the GARS family. (422 aa) |
| | Xaut_1415 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: rpe:RPE_4389 dihydroorotase, multifunctional complex type. (446 aa) |
| | Xaut_1420 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (178 aa) |
| | Xaut_1432 | PFAM: NAD-glutamate dehydrogenase; KEGG: bja:blr7995 hypothetical protein. (1611 aa) |
| | Xaut_1485 | PFAM: inositol monophosphatase; KEGG: rpb:RPB_1853 inositol-1(or 4)-monophosphatase. (278 aa) |
| | glsA-2 | PFAM: cyclic nucleotide-binding; Sulfate transporter/antisigma-factor antagonist STAS; glutaminase; KEGG: bja:bll4798 putative glutaminase; Belongs to the glutaminase family. (613 aa) |
| | Xaut_1616 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: pde:Pden_4664 shikimate dehydrogenase. (277 aa) |
| | aroK | Shikimate kinase., 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (594 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (164 aa) |
| | trpF | PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: rpe:RPE_0453 phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (270 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (405 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (281 aa) |
| | Xaut_1697 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: bra:BRADO0088 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (447 aa) |
| | purH | TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: rpa:RPA0028 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (529 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: rpd:RPD_0936 argininosuccinate lyase. (462 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (422 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (282 aa) |
| | Xaut_1939 | Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: glutamine synthetase family protein. (467 aa) |
| | Xaut_1940 | PFAM: FAD dependent oxidoreductase; KEGG: rsh:Rsph17029_2032 FAD dependent oxidoreductase. (439 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: nwi:Nwi_2803 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (409 aa) |
| | Xaut_2029 | PFAM: glutamine amidotransferase class-I; KEGG: bbt:BBta_0273 putative glutamine amidotransferase class-I. (288 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (386 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (457 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (363 aa) |
| | Xaut_2197 | Glycine dehydrogenase (decarboxylating); PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: glycine cleavage system P protein, subunit 2. (523 aa) |
| | gcvPA | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (446 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (125 aa) |
| | Xaut_2201 | TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: glycine cleavage system T protein. (381 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa) |
| | hisE | PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: bbt:BBta_0141 phosphoribosyl-ATP pyrophosphohydrolase. (108 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (258 aa) |
| | hisA | TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: bbt:BBta_0145 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-i midazolecarboxamide isomerase. (245 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (215 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: rpe:RPE_0370 imidazoleglycerol-phosphate dehydratase. (197 aa) |
| | dadA | D-amino-acid dehydrogenase; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family. (421 aa) |
| | purM | TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: bja:blr4125 5'-phosphoribosyl-5-aminoimidazole synthetase. (357 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (222 aa) |
| | Xaut_2336 | PFAM: glutamine synthetase catalytic region; KEGG: csa:Csal_1181 glutamate--ammonia ligase. (466 aa) |
| | thrB | TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: rpa:RPA4270 homoserine kinase; Belongs to the pseudomonas-type ThrB family. (321 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (514 aa) |
| | Xaut_2401 | PFAM: Colicin V production protein; KEGG: rpd:RPD_2996 colicin V production protein. (234 aa) |
| | Xaut_2403 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (357 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (278 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa) |
| | Xaut_2625 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: mlo:mll3437 aspartokinase, alpha and beta subunits; Belongs to the aspartokinase family. (419 aa) |
| | Xaut_2628 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: plt:Plut_0864 xanthine/uracil permeases-like. (598 aa) |
| | Xaut_2629 | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: bja:bll1421 prephenate dehydratase. (286 aa) |
| | Xaut_2703 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: bja:blr3858 putative shikimate 5-dehydrogenase. (268 aa) |
| | Xaut_2737 | PFAM: aminotransferase class I and II; KEGG: rpc:RPC_4122 aminotransferase, class I and II. (400 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: rpa:RPA4071 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1120 aa) |
| | Xaut_2818 | TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase; KEGG: bbt:BBta_1389 putative inositol monophosphatase family protein. (260 aa) |
| | Xaut_2830 | Methyltransferase type 11; PFAM: regulatory protein ArsR; UbiE/COQ5 methyltransferase; methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; KEGG: bov:BOV_1407 transcriptional regulator, ArsR family. (349 aa) |
| | Xaut_2831 | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: nha:Nham_0364 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (317 aa) |
| | Xaut_2832 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1271 aa) |
| | Xaut_3055 | PFAM: inositol monophosphatase; KEGG: mlo:mlr3921 putative myo-inositol-1(or 4)-monophosphatase. (262 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (510 aa) |
| | Xaut_3135 | PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: bbt:BBta_3822 hypothetical protein. (310 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (231 aa) |
| | Xaut_3184 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: sme:SMc04148 putative aminomethyltransferase protein; Belongs to the GcvT family. (772 aa) |
| | Xaut_3187 | PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: gbe:GbCGDNIH1_1826 aminomethyltransferase; Belongs to the GcvT family. (376 aa) |
| | Xaut_3234 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. (577 aa) |
| | Xaut_3295 | TIGRFAM: acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: acr:Acry_1162 peptidase M20. (409 aa) |
| | Xaut_3449 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1221 aa) |
| | aroQ-2 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (155 aa) |
| | Xaut_3506 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: pol:Bpro_2024 ornithine cyclodeaminase. (310 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | Xaut_3521 | PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: rpa:RPA2504 homoserine dehydrogenase. (428 aa) |
| | Xaut_3522 | PFAM: aminotransferase class I and II; KEGG: bja:blr4361 aminotransferase class I. (406 aa) |
| | Xaut_3524 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: bbt:BBta_0839 threonine synthase. (470 aa) |
| | Xaut_3580 | PFAM: GCN5-related N-acetyltransferase; KEGG: pau:PA14_12850 probable acetyltransferase. (186 aa) |
| | Xaut_3581 | PFAM: aminotransferase class IV; KEGG: rru:Rru_A1131 aminotransferase, class IV. (263 aa) |
| | Xaut_3582 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: rru:Rru_A1132 anthranilate synthase. (474 aa) |
| | Xaut_3585 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: bja:blr4949 glutamine synthetase I. (471 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (299 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (305 aa) |
| | Xaut_3849 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: bra:BRADO2830 adenylosuccinate lyase (adenylosuccinase) (ASL); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | Xaut_3918 | TIGRFAM: dihydroorotase, multifunctional complex type; PFAM: amidohydrolase; KEGG: nha:Nham_2283 dihydroorotase, multifunctional complex type. (438 aa) |
| | pyrB | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; KEGG: bja:blr5099 aspartate carbamoyl transferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (315 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (749 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (232 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (80 aa) |
| | purC | TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; KEGG: rpb:RPB_3719 phosphoribosylaminoimidazole-succinocarboxamide synthase. (264 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (370 aa) |
| | glyA-2 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (451 aa) |
| | Xaut_4302 | PFAM: Indole-3-glycerol phosphate synthase; KEGG: gsu:GSU2380 indole-3-glycerol phosphate synthase. (283 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: rpb:RPB_2798 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (263 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa) |
| | Xaut_4377 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: acr:Acry_1233 anthranilate phosphoribosyltransferase. (200 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (503 aa) |
| | Xaut_4394 | PFAM: aminotransferase class IV; KEGG: rpd:RPD_2593 aminotransferase, class IV. (285 aa) |
| | surE | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (280 aa) |
| | Xaut_4476 | KEGG: bja:blr1098 acetylornithine aminotransferase. (171 aa) |
| | Xaut_4533 | PFAM: aminotransferase class-III; KEGG: mag:amb0812 ornithine/acetylornithine aminotransferase. (233 aa) |
| | Xaut_4682 | PFAM: adenosine/AMP deaminase; KEGG: xac:XAC0308 adenosine deaminase. (519 aa) |
| | Xaut_4746 | PFAM: tRNA synthetase class II (G H P and S); KEGG: bra:BRADO6106 putative histidyl-tRNA synthetase. (392 aa) |
| | Xaut_4747 | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (324 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (350 aa) |
