STRINGSTRING
Xaut_3699 Xaut_3699 Xaut_3681 Xaut_3681 Xaut_3637 Xaut_3637 Xaut_3618 Xaut_3618 Xaut_3602 Xaut_3602 Xaut_3599 Xaut_3599 Xaut_3471 Xaut_3471 Xaut_3469 Xaut_3469 dnaE2-2 dnaE2-2 rpoC rpoC rpoB rpoB Xaut_3354 Xaut_3354 glyQ glyQ glyS glyS Xaut_3326 Xaut_3326 Xaut_3325 Xaut_3325 mutM mutM fmt fmt truA truA Xaut_3300 Xaut_3300 Xaut_3243 Xaut_3243 Xaut_3204 Xaut_3204 aspS aspS rnd rnd Xaut_3135 Xaut_3135 Xaut_3094 Xaut_3094 dnaE2 dnaE2 Xaut_0809 Xaut_0809 Xaut_0821 Xaut_0821 rlmE rlmE Xaut_1065 Xaut_1065 Xaut_1087 Xaut_1087 Xaut_1090 Xaut_1090 Xaut_1093 Xaut_1093 Xaut_1096 Xaut_1096 Xaut_1098 Xaut_1098 Xaut_1099 Xaut_1099 Xaut_0002 Xaut_0002 mutS mutS xerC xerC Xaut_0184 Xaut_0184 Xaut_0194 Xaut_0194 Xaut_0215 Xaut_0215 Xaut_0220 Xaut_0220 Xaut_0228 Xaut_0228 Xaut_0248 Xaut_0248 Xaut_0249 Xaut_0249 Xaut_0250 Xaut_0250 Xaut_0268 Xaut_0268 Xaut_0272 Xaut_0272 Xaut_0277 Xaut_0277 truB truB Xaut_0317 Xaut_0317 rsmI rsmI rlmN rlmN Xaut_0408 Xaut_0408 Xaut_0436 Xaut_0436 Xaut_0442 Xaut_0442 Xaut_0499 Xaut_0499 Xaut_0536 Xaut_0536 Xaut_0541 Xaut_0541 Xaut_0544 Xaut_0544 Xaut_0547 Xaut_0547 Xaut_0549 Xaut_0549 Xaut_0557 Xaut_0557 Xaut_0587 Xaut_0587 selA selA Xaut_0672 Xaut_0672 Xaut_0680 Xaut_0680 Xaut_0703 Xaut_0703 Xaut_0720 Xaut_0720 Xaut_0753 Xaut_0753 Xaut_0776 Xaut_0776 rnhA rnhA Xaut_1172 Xaut_1172 Xaut_1173 Xaut_1173 Xaut_1178 Xaut_1178 Xaut_1188 Xaut_1188 hisS hisS Xaut_1221 Xaut_1221 dnaG dnaG rnhB rnhB Xaut_1368 Xaut_1368 Xaut_1374 Xaut_1374 xseA xseA Xaut_1417 Xaut_1417 Xaut_1426 Xaut_1426 leuS leuS Xaut_1448 Xaut_1448 Xaut_1459 Xaut_1459 Xaut_1470 Xaut_1470 Xaut_1589 Xaut_1589 Xaut_1609 Xaut_1609 Xaut_1610 Xaut_1610 nth nth xerC-2 xerC-2 thrS thrS miaA miaA ligA ligA ybeY ybeY trmB trmB rho rho dnaQ dnaQ rsmG rsmG rsmH rsmH gyrB gyrB Xaut_1883 Xaut_1883 rnpA rnpA pheT pheT pheS pheS Xaut_1954 Xaut_1954 Xaut_1985 Xaut_1985 Xaut_2043 Xaut_2043 priA priA rlmH rlmH Xaut_2125 Xaut_2125 Xaut_2129 Xaut_2129 dnaX dnaX Xaut_2171 Xaut_2171 vapC vapC ileS ileS Xaut_2245 Xaut_2245 Xaut_2252 Xaut_2252 Xaut_2285 Xaut_2285 uvrC uvrC rnhA-2 rnhA-2 Xaut_2373 Xaut_2373 polA polA lysS lysS Xaut_2385 Xaut_2385 radA radA Xaut_2404 Xaut_2404 Xaut_2421 Xaut_2421 Xaut_2426 Xaut_2426 trmD trmD Xaut_2530 Xaut_2530 rph rph Xaut_2560 Xaut_2560 Xaut_2562 Xaut_2562 Xaut_2564 Xaut_2564 pth pth Xaut_2639 Xaut_2639 Xaut_2653 Xaut_2653 Xaut_2657 Xaut_2657 Xaut_2677 Xaut_2677 Xaut_2678 Xaut_2678 Xaut_2709 Xaut_2709 Xaut_2729 Xaut_2729 rlmJ rlmJ Xaut_2731 Xaut_2731 uvrB uvrB rsmA rsmA Xaut_2851 Xaut_2851 Xaut_2874 Xaut_2874 trmL trmL Xaut_2962 Xaut_2962 Xaut_2981 Xaut_2981 Xaut_2984 Xaut_2984 Xaut_2985 Xaut_2985 Xaut_2986 Xaut_2986 Xaut_2988 Xaut_2988 Xaut_2990 Xaut_2990 Xaut_3008 Xaut_3008 Xaut_3026 Xaut_3026 Xaut_3039 Xaut_3039 Xaut_3048 Xaut_3048 mutL mutL trpS trpS ruvB ruvB ruvA ruvA Xaut_0781 Xaut_0781 Xaut_0782 Xaut_0782 Xaut_0785 Xaut_0785 Xaut_0786 Xaut_0786 rpoA rpoA Xaut_4767 Xaut_4767 Xaut_4759 Xaut_4759 parE parE Xaut_4746 Xaut_4746 ruvC ruvC xseB xseB gltX2 gltX2 cysS cysS Xaut_4705 Xaut_4705 Xaut_4690 Xaut_4690 Xaut_4689 Xaut_4689 Xaut_4676 Xaut_4676 rne rne Xaut_4656 Xaut_4656 Xaut_4596 Xaut_4596 Xaut_4587 Xaut_4587 Xaut_4576 Xaut_4576 Xaut_4574 Xaut_4574 Xaut_4572 Xaut_4572 Xaut_4570 Xaut_4570 tyrS tyrS proS proS Xaut_4415 Xaut_4415 serS serS Xaut_4401 Xaut_4401 gltX1 gltX1 Xaut_4365 Xaut_4365 Xaut_4330 Xaut_4330 metG metG Xaut_4326 Xaut_4326 gyrA gyrA uvrA uvrA trmFO trmFO Xaut_4306 Xaut_4306 Xaut_4284 Xaut_4284 tgt tgt queA queA mfd mfd dusA dusA argS argS Xaut_4240 Xaut_4240 valS valS Xaut_4211 Xaut_4211 Xaut_4164 Xaut_4164 alaS alaS recA recA Xaut_4009 Xaut_4009 Xaut_4003 Xaut_4003 gatB gatB gatA gatA gatC gatC vapC-2 vapC-2 topA topA parC parC rnc rnc rnr rnr dinB dinB Xaut_3841 Xaut_3841 Xaut_3840 Xaut_3840 rpoZ rpoZ Xaut_3836 Xaut_3836 Xaut_3835 Xaut_3835 Xaut_3735 Xaut_3735 Xaut_3734 Xaut_3734
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
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Xaut_3699PFAM: C-5 cytosine-specific DNA methylase; KEGG: mlo:mlr8517 modification methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (579 aa)
Xaut_3681PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: mhu:Mhun_0639 exonuclease. (200 aa)
Xaut_3637TIGRFAM: phage head-tail adaptor, putative; KEGG: reu:Reut_A2398 putative bacteriophage protein. (123 aa)
Xaut_3618PFAM: MT-A70 family protein; KEGG: sit:TM1040_1679 MT-A70; Belongs to the MT-A70-like family. (194 aa)
Xaut_3602PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: mmr:Mmar10_0016 DNA polymerase I. (299 aa)
Xaut_3599KEGG: rsq:Rsph17025_1727 hypothetical protein. (117 aa)
Xaut_3471PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL110144 putative transposon/insertion element protein. (88 aa)
Xaut_3469KEGG: rpc:RPC_1732 hypothetical protein. (480 aa)
dnaE2-2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1116 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1394 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1358 aa)
Xaut_3354TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: rpb:RPB_2203 RNA methyltransferase TrmH, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (288 aa)
glyQTIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit; KEGG: rpb:RPB_1093 glycyl-tRNA synthetase, alpha subunit. (310 aa)
glySTIGRFAM: glycyl-tRNA synthetase, beta subunit; KEGG: rpc:RPC_4348 glycine--tRNA ligase. (733 aa)
Xaut_3326KEGG: mlo:mll0558 hypothetical protein. (225 aa)
Xaut_3325PFAM: beta-lactamase domain protein; KEGG: bja:bll1142 hypothetical protein. (247 aa)
mutMformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (293 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (307 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (245 aa)
Xaut_3300TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: bbt:BBta_0090 putative helicase-exonuclease type V protein family, AddA subunit; Belongs to the helicase family. UvrD subfamily. (1167 aa)
Xaut_3243PFAM: Amidase; KEGG: rfr:Rfer_0989 amidase; Belongs to the amidase family. (474 aa)
Xaut_3204PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: nwi:Nwi_0314 DEAD/DEAH box helicase. (559 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (623 aa)
rndRibonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (382 aa)
Xaut_3135PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: bbt:BBta_3822 hypothetical protein. (310 aa)
Xaut_3094PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: atc:AGR_C_1238 ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family. (620 aa)
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1059 aa)
Xaut_0809KEGG: mes:Meso_3808 hypothetical protein. (507 aa)
Xaut_0821Recombinase; PFAM: Resolvase domain; Recombinase; KEGG: pde:Pden_3123 recombinase. (662 aa)
rlmERibosomal RNA methyltransferase RrmJ/FtsJ; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (254 aa)
Xaut_1065PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL110144 putative transposon/insertion element protein. (88 aa)
Xaut_1087SMART: AAA ATPase; KEGG: pth:PTH_2877 hypothetical protein. (590 aa)
Xaut_1090PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: acr:Acry_3553 resolvase, N-terminal domain. (159 aa)
Xaut_1093PFAM: transposase IS3/IS911 family protein; KEGG: mag:amb3265 insertion element ISR1 hypothetical 10 kDa protein A3. (84 aa)
Xaut_1096PFAM: putative RNA methylase; N-6 DNA methylase; KEGG: rpc:RPC_3652 N-6 DNA methylase. (486 aa)
Xaut_1098PFAM: helicase domain protein; type III restriction protein res subunit; protein of unknown function DUF450; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: rpc:RPC_3651 type III restriction enzyme, res subunit. (1124 aa)
Xaut_1099PFAM: Resolvase domain; KEGG: jan:Jann_2896 resolvase-like. (212 aa)
Xaut_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (373 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (921 aa)
xerCIntegrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (342 aa)
Xaut_0184KEGG: bbt:BBta_0756 putative membrane protein of unknown function. (360 aa)
Xaut_0194TIGRFAM: exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: bja:blr0618 exodeoxyribonuclease III. (290 aa)
Xaut_0215PFAM: integrase family protein; KEGG: rsp:RSP_2361 putative integrase/resolvase recombinase protein phage-related integrase; Belongs to the 'phage' integrase family. (550 aa)
Xaut_0220PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL110144 putative transposon/insertion element protein. (88 aa)
Xaut_0228KEGG: hhe:HH1420 hypothetical protein. (703 aa)
Xaut_0248PFAM: Resolvase domain; KEGG: mes:Meso_3805 resolvase-like. (524 aa)
Xaut_0249KEGG: nwi:Nwi_2412 ISBm1, transposase orfA. (132 aa)
Xaut_0250PFAM: transposase IS4 family protein; KEGG: nwi:Nwi_1095 transposase, IS4. (142 aa)
Xaut_0268PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_4139 transposase IS116/IS110/IS902. (350 aa)
Xaut_0272TIGRFAM: Ti-type conjugative transfer relaxase TraA; PFAM: MobA/MobL protein; KEGG: rpc:RPC_0149 MobA/MobL protein. (976 aa)
Xaut_0277PFAM: Resolvase domain; Recombinase; KEGG: bbt:BBta_0430 putative resolvase. (551 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (363 aa)
Xaut_0317PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: bov:BOV_A0838 hypothetical protein. (169 aa)
rsmIUroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (320 aa)
rlmNRadical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (414 aa)
Xaut_04082'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (176 aa)
Xaut_0436PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tvo:TVN1476 adenine specific DNA methylase (Mod-related). (696 aa)
Xaut_0442TIGRFAM: Ti-type conjugative transfer relaxase TraA; PFAM: MobA/MobL protein; KEGG: bbt:BBta_6372 putative conjugal transfer protein, TraA. (985 aa)
Xaut_0499PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: mlo:mll9195 transposase. (370 aa)
Xaut_0536PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: art:Arth_0466 resolvase. (203 aa)
Xaut_0541Hypothetical protein. (102 aa)
Xaut_0544PFAM: Relaxase/mobilization nuclease family protein; KEGG: nha:Nham_0596 hypothetical protein. (562 aa)
Xaut_0547PFAM: DNA methylase N-4/N-6 domain protein; KEGG: tbd:Tbd_1491 adenine specific DNA-methyltransferase. (752 aa)
Xaut_0549PFAM: type III restriction protein res subunit; KEGG: deb:DehaBAV1_1044 type III restriction enzyme, res subunit. (890 aa)
Xaut_0557PFAM: transposase IS4 family protein; KEGG: swi:Swit_4905 transposase, IS4 family protein. (458 aa)
Xaut_0587PFAM: transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr6190 transposase. (362 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (485 aa)
Xaut_0672PFAM: UvrD/REP helicase; KEGG: sat:SYN_02908 ATP-dependent DNA helicase. (595 aa)
Xaut_0680PFAM: SNF2-related protein; helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: swi:Swit_0196 helicase domain protein. (1167 aa)
Xaut_0703PFAM: transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr6190 transposase. (362 aa)
Xaut_0720KEGG: pde:Pden_1533 probable methylase/helicase. (1440 aa)
Xaut_0753PFAM: transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr6190 transposase. (362 aa)
Xaut_0776PFAM: UvrD/REP helicase; protein of unknown function DUF955; KEGG: vei:Veis_3742 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1143 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (245 aa)
Xaut_1172A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (355 aa)
Xaut_1173PFAM: DNA methylase N-4/N-6 domain protein; KEGG: rpb:RPB_1073 DNA methylase N-4/N-6; Belongs to the N(4)/N(6)-methyltransferase family. (389 aa)
Xaut_1178PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: mes:Meso_2208 tRNA/rRNA methyltransferase (SpoU). (268 aa)
Xaut_1188PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases; KEGG: bbt:BBta_0802 putative ATP dependent DNA helicase. (930 aa)
hisSTIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; KEGG: mes:Meso_0422 histidyl-tRNA synthetase. (509 aa)
Xaut_1221KEGG: ret:RHE_PE00117 putative amidase protein. (149 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. (639 aa)
rnhBRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (249 aa)
Xaut_1368KEGG: rpe:RPE_2213 hypothetical protein. (170 aa)
Xaut_1374KEGG: rpc:RPC_4353 hypothetical protein. (75 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (496 aa)
Xaut_1417TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; KEGG: bja:bll2553 3-methyladenine-DNA glycosylase. (223 aa)
Xaut_1426PFAM: UvrD/REP helicase; KEGG: nwi:Nwi_2360 UvrD/REP helicase. (817 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: rpb:RPB_0385 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (894 aa)
Xaut_1448TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: nha:Nham_0100 DNA polymerase III, delta subunit. (342 aa)
Xaut_1459PFAM: DNA polymerase III chi subunit HolC; KEGG: rpa:RPA3059 DNA polymerase III chi subunit. (153 aa)
Xaut_1470PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: rpe:RPE_0725 ATP dependent DNA ligase. (542 aa)
Xaut_1589PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: rpc:RPC_0876 DEAD/DEAH box helicase-like; Belongs to the DEAD box helicase family. (609 aa)
Xaut_1609PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL110144 putative transposon/insertion element protein. (88 aa)
Xaut_1610PFAM: transposase IS3/IS911 family protein; KEGG: mag:amb3265 insertion element ISR1 hypothetical 10 kDa protein A3. (97 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (359 aa)
xerC-2Integrase family protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (354 aa)
thrSthreonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (660 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa)
ligADNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (720 aa)
ybeYProtein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (176 aa)
trmBtRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (231 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (422 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (240 aa)
rsmGGlucose inhibited division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (245 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (345 aa)
gyrBDNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (813 aa)
Xaut_1883PFAM: pseudouridine synthase; KEGG: bja:blr0474 hypothetical protein. (264 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (187 aa)
pheTTIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: rpb:RPB_0047 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (804 aa)
pheSTIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: bbt:BBta_0214 phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (373 aa)
Xaut_1954TIGRFAM: methyltransferase FkbM family; KEGG: mul:MUL_4688 hypothetical protein. (272 aa)
Xaut_1985TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: rpa:RPA0368 possible pseudouridine synthases; Belongs to the pseudouridine synthase RluA family. (377 aa)
Xaut_2043PFAM: protein of unknown function UPF0005; KEGG: atc:AGR_C_4861 conserved hypothetical integral membrane protein; Belongs to the BI1 family. (261 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (727 aa)
rlmHProtein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (160 aa)
Xaut_2125KEGG: mlo:mll6859 hypothetical protein. (107 aa)
Xaut_2129TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent domain protein; SMART: DEAD-like helicases; KEGG: rpe:RPE_4818 ATP-dependent helicase HrpB. (837 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (622 aa)
Xaut_2171KEGG: neu:NE0256 hypothetical protein. (469 aa)
vapCPilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (141 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (1012 aa)
Xaut_2245PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: acr:Acry_3553 resolvase, N-terminal domain. (183 aa)
Xaut_2252PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL120646 putative transposase-related protein. (131 aa)
Xaut_2285PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: mlo:mll9195 transposase. (370 aa)
uvrCExcinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (779 aa)
rnhA-2Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (151 aa)
Xaut_2373TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: nwi:Nwi_2596 phage SPO1 DNA polymerase-related protein. (307 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (1000 aa)
lysSTIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase class 1c; KEGG: rpa:RPA4685 lysyl tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (565 aa)
Xaut_2385PFAM: transposase IS3/IS911 family protein; KEGG: bja:blr2053 putative transposase. (70 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (489 aa)
Xaut_2404Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (493 aa)
Xaut_2421TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: rle:RL0289 hypothetical protein; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (157 aa)
Xaut_2426KEGG: pde:Pden_5114 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (719 aa)
trmDtRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (242 aa)
Xaut_2530Lysine--tRNA ligase; PFAM: tRNA synthetase class II (D K and N); KEGG: asparaginyl-tRNA synthetase, putative. (363 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (237 aa)
Xaut_2560KEGG: mca:MCA2306 tRNA nucleotidyltransferase/poly(A) polymerase family protein. (303 aa)
Xaut_2562PFAM: PilT protein domain protein; KEGG: atc:AGR_L_3577 hypothetical protein. (135 aa)
Xaut_2564KEGG: pnu:Pnuc_1164 hypothetical protein. (431 aa)
pthAminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (202 aa)
Xaut_2639PFAM: helicase domain protein; KEGG: rpe:RPE_0127 helicase domain protein. (1101 aa)
Xaut_2653TIGRFAM: Ti-type conjugative transfer relaxase TraA; PFAM: MobA/MobL protein; KEGG: rpc:RPC_0149 MobA/MobL protein. (976 aa)
Xaut_2657PFAM: transposase IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: nha:Nham_4139 transposase IS116/IS110/IS902. (350 aa)
Xaut_2677PFAM: transposase IS4 family protein; KEGG: nwi:Nwi_1095 transposase, IS4. (142 aa)
Xaut_2678KEGG: nwi:Nwi_2412 ISBm1, transposase orfA. (132 aa)
Xaut_2709KEGG: bbt:BBta_0480 putative transposase. (130 aa)
Xaut_2729PFAM: Glutathione S-transferase domain; KEGG: pmy:Pmen_0226 glutathione S-transferase, N-terminal domain. (227 aa)
rlmJProtein of unknown function DUF519; Specifically methylates the adenine in position 2030 of 23S rRNA. (286 aa)
Xaut_2731PFAM: ribonuclease T2; KEGG: bja:blr7466 ribonuclease; Belongs to the RNase T2 family. (220 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (866 aa)
rsmADimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (288 aa)
Xaut_2851PFAM: Resolvase domain; Recombinase; KEGG: swi:Swit_3384 resolvase, N-terminal domain. (565 aa)
Xaut_2874PFAM: transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr6190 transposase. (362 aa)
trmLtRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (154 aa)
Xaut_2962PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: vfi:VF1465 superfamily I DNA and RNA helicases. (170 aa)
Xaut_2981PFAM: helicase domain protein; KEGG: gme:Gmet_3058 helicase-like. (1002 aa)
Xaut_2984PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: rpa:RPA2214 possible helicase. (1113 aa)
Xaut_2985PFAM: UvrD/REP helicase; KEGG: rpa:RPA2215 possible ATP-dependent exodeoxyribonuclease (subunit A); Belongs to the helicase family. UvrD subfamily. (1131 aa)
Xaut_2986KEGG: rpa:RPA2216 hypothetical protein. (884 aa)
Xaut_2988PFAM: SNF2-related protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicases; KEGG: swi:Swit_0196 helicase domain protein. (1167 aa)
Xaut_2990Putative ATPase; KEGG: rpa:RPA2219 possible ATPase. (1406 aa)
Xaut_3008PFAM: transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr6190 transposase. (362 aa)
Xaut_3026KEGG: mes:Meso_3828 probably methylase/helicase. (1447 aa)
Xaut_3039PFAM: transposase IS4 family protein; KEGG: psb:Psyr_0095 transposase, IS4. (473 aa)
Xaut_3048PFAM: UvrD/REP helicase; KEGG: sat:SYN_02908 ATP-dependent DNA helicase. (608 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (643 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (345 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (343 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
Xaut_0781KEGG: bja:blr8087 hypothetical protein. (886 aa)
Xaut_0782PFAM: UvrD/REP helicase; KEGG: bja:blr8088 hypothetical protein. (1107 aa)
Xaut_0785PFAM: type III restriction protein res subunit; protein of unknown function DUF450; EcoEI R domain protein; SMART: DEAD-like helicases; KEGG: nwi:Nwi_0270 DEAD/DEAH box helicase. (791 aa)
Xaut_0786PFAM: N-6 DNA methylase; KEGG: vvy:VV0266 type I restriction-modification system methyltransferase subunit. (710 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (338 aa)
Xaut_4767TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: bja:bll5366 putative ribosomal large subunit pseudouridine synthase C; Belongs to the pseudouridine synthase RluA family. (364 aa)
Xaut_4759PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: rpe:RPE_2959 DEAD/DEAH box helicase domain protein; Belongs to the DEAD box helicase family. (537 aa)
parEDNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (678 aa)
Xaut_4746PFAM: tRNA synthetase class II (G H P and S); KEGG: bra:BRADO6106 putative histidyl-tRNA synthetase. (392 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (169 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (97 aa)
gltX2glutamyl-tRNA synthetase class Ic; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (458 aa)
cysSTIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; KEGG: bbt:BBta_3498 cysteine tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa)
Xaut_4705TIGRFAM: Allophanate hydrolase; PFAM: Amidase; KEGG: bbt:BBta_0724 putative glutamyl-tRNA(Gln) amidotransferase subunit A (Glu-ADT subunit A). (596 aa)
Xaut_4690PFAM: type III restriction protein res subunit; KEGG: rru:Rru_A0242 type III restriction enzyme, res subunit. (999 aa)
Xaut_4689Hypothetical protein; KEGG: vei:Veis_4172 DNA methylase N-4/N-6 domain protein. (241 aa)
Xaut_4676Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: rpe:RPE_3442 deoxyribodipyrimidine photo-lyase. (500 aa)
rneRibonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1080 aa)
Xaut_4656TIGRFAM: Amidohydrolase AtzE type; PFAM: Amidase; KEGG: rpa:RPA1469 possible glutamyl-tRNA (Gln) amidotransferase subunit A. (482 aa)
Xaut_4596PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL70042 putative insertion sequence protein. (146 aa)
Xaut_4587PFAM: protein of unknown function DUF1520; KEGG: sme:SMa1082 hypothetical protein. (199 aa)
Xaut_4576ATPase-like protein; KEGG: sat:SYN_01822 ATPase. (664 aa)
Xaut_4574PFAM: PilT protein domain protein; KEGG: rpe:RPE_3246 PilT protein domain protein. (147 aa)
Xaut_4572PFAM: Resolvase domain; Recombinase; KEGG: pde:Pden_3123 recombinase. (584 aa)
Xaut_4570TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: rpd:RPD_1738 RNA methyltransferase TrmH, group 1. (298 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (416 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (440 aa)
Xaut_4415PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: nha:Nham_2055 DEAD/DEAH box helicase-like. (697 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (468 aa)
Xaut_4401Putative TIM-barrel protein, nifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (345 aa)
gltX1glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (471 aa)
Xaut_4365TIGRFAM: DNA ligase D; DNA ligase D 3'-phosphoesterase domain; DNA polymerase LigD polymerase domain; DNA polymerase LigD ligase region; PFAM: DNA primase small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: mlo:mll9625 DNA ligase. (886 aa)
Xaut_4330TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: mlo:mll0418 putative deoxyribonuclease. (273 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (550 aa)
Xaut_4326KEGG: nha:Nham_2009 DNA-directed DNA polymerase. (347 aa)
gyrADNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (914 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (1039 aa)
trmFOGid protein; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (471 aa)
Xaut_4306TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: mag:amb4254 superfamily II DNA helicase. (607 aa)
Xaut_4284KEGG: bbt:BBta_4522 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1150 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (384 aa)
queAQueuosine biosynthesis protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (362 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1168 aa)
dusATIM-barrel protein, yjbN family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (330 aa)
argSTIGRFAM: arginyl-tRNA synthetase; KEGG: rpa:RPA2854 arginyl-tRNA synthetase. (586 aa)
Xaut_4240TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rpc:RPC_2496 exodeoxyribonuclease III (xth). (262 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (930 aa)
Xaut_4211KEGG: rpb:RPB_1667 hypothetical protein. (501 aa)
Xaut_4164KEGG: bra:BRADO2158 putative RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (408 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (884 aa)
recArecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (361 aa)
Xaut_4009PFAM: transposase IS116/IS110/IS902 family protein; KEGG: mlo:mlr6190 transposase. (362 aa)
Xaut_4003PFAM: transposase IS116/IS110/IS902 family protein; KEGG: bja:bll1545 putative transposase. (340 aa)
gatBglutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (496 aa)
gatAglutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (494 aa)
gatCglutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa)
vapC-2PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (121 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (901 aa)
parCDNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (745 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (236 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (776 aa)
dinBDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (432 aa)
Xaut_3841PFAM: HhH-GPD family protein; KEGG: rpc:RPC_4886 HhH-GPD. (217 aa)
Xaut_3840PFAM: glutamyl-tRNA synthetase class Ic; KEGG: bra:BRADO6498 putative glutamyl-tRNA synthetase, class Ic; Belongs to the class-I aminoacyl-tRNA synthetase family. (315 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (129 aa)
Xaut_3836PFAM: protein of unknown function DUF88; KEGG: nwi:Nwi_1924 protein of unknown function DUF88. (202 aa)
Xaut_3835PFAM: Uracil-DNA glycosylase superfamily; KEGG: nha:Nham_2258 uracil-DNA glycosylase superfamily. (233 aa)
Xaut_3735PFAM: transposase IS3/IS911 family protein; KEGG: rle:pRL110144 putative transposon/insertion element protein. (107 aa)
Xaut_3734PFAM: transposase IS116/IS110/IS902 family protein; KEGG: bja:bll1545 putative transposase. (340 aa)
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
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