STRINGSTRING
Xaut_3922 Xaut_3922 vapC-2 vapC-2 rne rne xseB xseB Xaut_4751 Xaut_4751 polA polA rnhA-2 rnhA-2 vapC vapC rnpA rnpA dnaQ dnaQ rnhA rnhA Xaut_1094 Xaut_1094 Xaut_0782 Xaut_0782 Xaut_0781 Xaut_0781 Xaut_0776 Xaut_0776 Xaut_0673 Xaut_0673 Xaut_0068 Xaut_0068 ybeY ybeY nth nth xseA xseA rnhB rnhB Xaut_2986 Xaut_2986 Xaut_3047 Xaut_3047 Xaut_3049 Xaut_3049 ruvC ruvC rnd rnd Xaut_3299 Xaut_3299 Xaut_3300 Xaut_3300 Xaut_3602 Xaut_3602 Xaut_3681 Xaut_3681 Xaut_3843 Xaut_3843 rnr rnr rnc rnc
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Xaut_3922Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (176 aa)
vapC-2PilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (121 aa)
rneRibonuclease, Rne/Rng family; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1080 aa)
xseBExodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (97 aa)
Xaut_4751TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: rpc:RPC_2813 single-stranded-DNA-specific exonuclease RecJ. (626 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (1000 aa)
rnhA-2Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (151 aa)
vapCPilT protein domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (141 aa)
rnpARibonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (187 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (240 aa)
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (245 aa)
Xaut_1094PFAM: restriction endonuclease; KEGG: zmo:ZMO0028 mrr restriction system protein. (310 aa)
Xaut_0782PFAM: UvrD/REP helicase; KEGG: bja:blr8088 hypothetical protein. (1107 aa)
Xaut_0781KEGG: bja:blr8087 hypothetical protein. (886 aa)
Xaut_0776PFAM: UvrD/REP helicase; protein of unknown function DUF955; KEGG: vei:Veis_3742 UvrD/REP helicase; Belongs to the helicase family. UvrD subfamily. (1143 aa)
Xaut_0673KEGG: sat:SYN_02907 ATP-dependent endonuclease family protein. (619 aa)
Xaut_0068PFAM: 3'-5' exonuclease; KEGG: rpa:RPA0046 3'-5' exonuclease. (206 aa)
ybeYProtein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (176 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (359 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (496 aa)
rnhBRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (249 aa)
Xaut_2986KEGG: rpa:RPA2216 hypothetical protein. (884 aa)
Xaut_3047KEGG: sat:SYN_02907 ATP-dependent endonuclease family protein. (598 aa)
Xaut_3049PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: mag:amb2073 DNA polymerase III epsilon subunit and related 3'-5' exonuclease. (298 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (169 aa)
rndRibonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (382 aa)
Xaut_3299TIGRFAM: Double-strand break repair protein AddB; KEGG: bbt:BBta_0089 putative helicase-exonuclease type V protein family, AddB subunit. (1015 aa)
Xaut_3300TIGRFAM: Double-strand break repair helicase AddA; PFAM: UvrD/REP helicase; KEGG: bbt:BBta_0090 putative helicase-exonuclease type V protein family, AddA subunit; Belongs to the helicase family. UvrD subfamily. (1167 aa)
Xaut_3602PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein class 2; KEGG: mmr:Mmar10_0016 DNA polymerase I. (299 aa)
Xaut_3681PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: mhu:Mhun_0639 exonuclease. (200 aa)
Xaut_3843PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: nwi:Nwi_0745 HNH endonuclease. (196 aa)
rnrRibonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (776 aa)
rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (236 aa)
Your Current Organism:
Xanthobacter autotrophicus
NCBI taxonomy Id: 78245
Other names: X. autotrophicus Py2, Xanthobacter autotrophicus Py2, Xanthobacter autotrophicus str. Py2, Xanthobacter autotrophicus strain Py2, Xanthobacter sp. Py2
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