12 items (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC103174237	HELICc2 domain-containing protein. (108 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	gtf2e1	General transcription factor IIE subunit 1. (429 aa)
	ccnh	CYCLIN domain-containing protein; Belongs to the cyclin family. (340 aa)
	ercc3	Uncharacterized protein. (783 aa)
	gtf2b	TFIIB-type domain-containing protein. (321 aa)
	gtf2h2	General transcription factor IIH subunit. (398 aa)
	gtf2h1	Uncharacterized protein. (592 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (288 aa)
	gtf2h5	General transcription factor IIH subunit 5. (71 aa)
	gtf2h3	Uncharacterized protein. (320 aa)
	gtf2e2	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (289 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103174237	ccnh	ENSCMIP00000001786	ENSCMIP00000015958	HELICc2 domain-containing protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.996
LOC103174237	ercc3	ENSCMIP00000001786	ENSCMIP00000016348	HELICc2 domain-containing protein.	Uncharacterized protein.	0.999
LOC103174237	gtf2b	ENSCMIP00000001786	ENSCMIP00000016617	HELICc2 domain-containing protein.	TFIIB-type domain-containing protein.	0.984
LOC103174237	gtf2e1	ENSCMIP00000001786	ENSCMIP00000007171	HELICc2 domain-containing protein.	General transcription factor IIE subunit 1.	0.959
LOC103174237	gtf2e2	ENSCMIP00000001786	ENSCMIP00000036765	HELICc2 domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.996
LOC103174237	gtf2f2	ENSCMIP00000001786	ENSCMIP00000027489	HELICc2 domain-containing protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.973
LOC103174237	gtf2h1	ENSCMIP00000001786	ENSCMIP00000025830	HELICc2 domain-containing protein.	Uncharacterized protein.	0.999
LOC103174237	gtf2h2	ENSCMIP00000001786	ENSCMIP00000017953	HELICc2 domain-containing protein.	General transcription factor IIH subunit.	0.999
LOC103174237	gtf2h3	ENSCMIP00000001786	ENSCMIP00000033644	HELICc2 domain-containing protein.	Uncharacterized protein.	0.999
LOC103174237	gtf2h5	ENSCMIP00000001786	ENSCMIP00000029167	HELICc2 domain-containing protein.	General transcription factor IIH subunit 5.	0.985
LOC103174237	mnat1	ENSCMIP00000001786	ENSCMIP00000006614	HELICc2 domain-containing protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.999
ccnh	LOC103174237	ENSCMIP00000015958	ENSCMIP00000001786	CYCLIN domain-containing protein; Belongs to the cyclin family.	HELICc2 domain-containing protein.	0.996
ccnh	ercc3	ENSCMIP00000015958	ENSCMIP00000016348	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.989
ccnh	gtf2b	ENSCMIP00000015958	ENSCMIP00000016617	CYCLIN domain-containing protein; Belongs to the cyclin family.	TFIIB-type domain-containing protein.	0.951
ccnh	gtf2e1	ENSCMIP00000015958	ENSCMIP00000007171	CYCLIN domain-containing protein; Belongs to the cyclin family.	General transcription factor IIE subunit 1.	0.949
ccnh	gtf2e2	ENSCMIP00000015958	ENSCMIP00000036765	CYCLIN domain-containing protein; Belongs to the cyclin family.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.994
ccnh	gtf2f2	ENSCMIP00000015958	ENSCMIP00000027489	CYCLIN domain-containing protein; Belongs to the cyclin family.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.901
ccnh	gtf2h1	ENSCMIP00000015958	ENSCMIP00000025830	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.991
ccnh	gtf2h2	ENSCMIP00000015958	ENSCMIP00000017953	CYCLIN domain-containing protein; Belongs to the cyclin family.	General transcription factor IIH subunit.	0.991
ccnh	gtf2h3	ENSCMIP00000015958	ENSCMIP00000033644	CYCLIN domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.998