18 items (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCMIP00000000101	annotation not available (154 aa)
	LOC103174112	PINIT domain-containing protein. (146 aa)
	sumo2	Small ubiquitin-related modifier. (113 aa)
	sae1	ThiF domain-containing protein. (350 aa)
	LOC103191468	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1181 aa)
	rangap1	RanGAP1_C domain-containing protein. (521 aa)
	sumo1	Small ubiquitin-related modifier. (111 aa)
	ENSCMIP00000012412	ULP_PROTEASE domain-containing protein. (293 aa)
	ube2i	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (172 aa)
	LOC103186049	Small ubiquitin-related modifier. (124 aa)
	LOC103183812	Small ubiquitin-related modifier. (107 aa)
	LOC103190991	DTHCT domain-containing protein. (504 aa)
	uspl1	USP domain-containing protein. (1043 aa)
	V9KIV1_CALMI	Zinc finger MIZ domain-containing protein 1-like protein. (348 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (649 aa)
	znf451	Uncharacterized protein. (1059 aa)
	ENSCMIP00000047803	ULP_PROTEASE domain-containing protein. (339 aa)
	Kctd2	Uncharacterized protein. (63 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000000101	LOC103190991	ENSCMIP00000000101	ENSCMIP00000018976	annotation not available	DTHCT domain-containing protein.	0.626
ENSCMIP00000000101	LOC103191468	ENSCMIP00000000101	ENSCMIP00000009704	annotation not available	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	0.626
ENSCMIP00000012412	ENSCMIP00000047803	ENSCMIP00000012412	ENSCMIP00000047803	ULP_PROTEASE domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.784
ENSCMIP00000012412	Kctd2	ENSCMIP00000012412	ENSCMIP00000049169	ULP_PROTEASE domain-containing protein.	Uncharacterized protein.	0.433
ENSCMIP00000012412	LOC103183812	ENSCMIP00000012412	ENSCMIP00000018808	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.849
ENSCMIP00000012412	LOC103186049	ENSCMIP00000012412	ENSCMIP00000018701	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.896
ENSCMIP00000012412	rangap1	ENSCMIP00000012412	ENSCMIP00000010646	ULP_PROTEASE domain-containing protein.	RanGAP1_C domain-containing protein.	0.786
ENSCMIP00000012412	sae1	ENSCMIP00000012412	ENSCMIP00000003065	ULP_PROTEASE domain-containing protein.	ThiF domain-containing protein.	0.574
ENSCMIP00000012412	sumo1	ENSCMIP00000012412	ENSCMIP00000011551	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.849
ENSCMIP00000012412	sumo2	ENSCMIP00000012412	ENSCMIP00000001390	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.896
ENSCMIP00000012412	uba2	ENSCMIP00000012412	ENSCMIP00000036213	ULP_PROTEASE domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.582
ENSCMIP00000012412	ube2i	ENSCMIP00000012412	ENSCMIP00000014219	ULP_PROTEASE domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.492
ENSCMIP00000047803	ENSCMIP00000012412	ENSCMIP00000047803	ENSCMIP00000012412	ULP_PROTEASE domain-containing protein.	ULP_PROTEASE domain-containing protein.	0.784
ENSCMIP00000047803	Kctd2	ENSCMIP00000047803	ENSCMIP00000049169	ULP_PROTEASE domain-containing protein.	Uncharacterized protein.	0.539
ENSCMIP00000047803	LOC103183812	ENSCMIP00000047803	ENSCMIP00000018808	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.819
ENSCMIP00000047803	LOC103186049	ENSCMIP00000047803	ENSCMIP00000018701	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.863
ENSCMIP00000047803	rangap1	ENSCMIP00000047803	ENSCMIP00000010646	ULP_PROTEASE domain-containing protein.	RanGAP1_C domain-containing protein.	0.721
ENSCMIP00000047803	sae1	ENSCMIP00000047803	ENSCMIP00000003065	ULP_PROTEASE domain-containing protein.	ThiF domain-containing protein.	0.516
ENSCMIP00000047803	sumo1	ENSCMIP00000047803	ENSCMIP00000011551	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.819
ENSCMIP00000047803	sumo2	ENSCMIP00000047803	ENSCMIP00000001390	ULP_PROTEASE domain-containing protein.	Small ubiquitin-related modifier.	0.863