STRINGSTRING
hdac11 hdac11 hint3 hint3 LOC103182478 LOC103182478 LOC103182479 LOC103182479 aga aga acer2 acer2 hdac8 hdac8 fhit fhit sirt5 sirt5 nit1 nit1 acy1 acy1 pdf pdf sirt1 sirt1 hdac2 hdac2 pglyrp2 pglyrp2 sirt4 sirt4 LOC103185597 LOC103185597 upb1 upb1 acer3 acer3 aspg aspg LOC103179899 LOC103179899 asah1 asah1 hdac4 hdac4 hdac1 hdac1 gls gls ENSCMIP00000037495 ENSCMIP00000037495 ngly1 ngly1 nadsyn1 nadsyn1 afmid afmid LOC103179020 LOC103179020 ENSCMIP00000042614 ENSCMIP00000042614 LOC103183483 LOC103183483 sirt6 sirt6 btd btd sirt7 sirt7 LOC103180876 LOC103180876 nit2 nit2 faah2 faah2 naaa naaa hdac3 hdac3 hdac9 hdac9 sirt2 sirt2 amdhd2 amdhd2 hdac5 hdac5 wdyhv1 wdyhv1 sirt3 sirt3 cat cat faah faah ntan1 ntan1 LOC103191067 LOC103191067 ENSCMIP00000025625 ENSCMIP00000025625 pigl pigl aspa aspa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hdac11Hist_deacetyl domain-containing protein. (350 aa)
hint3HIT domain-containing protein. (204 aa)
LOC103182478M20_dimer domain-containing protein. (523 aa)
LOC103182479M20_dimer domain-containing protein. (544 aa)
agaUncharacterized protein. (337 aa)
acer2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (274 aa)
hdac8Hist_deacetyl domain-containing protein. (356 aa)
fhitBis(5'-adenosyl)-triphosphatase. (150 aa)
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (309 aa)
nit1CN hydrolase domain-containing protein. (348 aa)
acy1M20_dimer domain-containing protein. (449 aa)
pdfPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (236 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (631 aa)
hdac2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (509 aa)
pglyrp2PGRP domain-containing protein. (389 aa)
sirt4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (323 aa)
LOC103185597Uncharacterized protein. (314 aa)
upb1CN hydrolase domain-containing protein. (417 aa)
acer3Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (139 aa)
aspgUncharacterized protein. (428 aa)
LOC103179899NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (328 aa)
asah1Uncharacterized protein; Belongs to the acid ceramidase family. (391 aa)
hdac4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1090 aa)
hdac1Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (505 aa)
glsANK_REP_REGION domain-containing protein. (569 aa)
ENSCMIP00000037495Hist_deacetyl domain-containing protein. (571 aa)
ngly1PAW domain-containing protein. (732 aa)
nadsyn1Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (710 aa)
afmidKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (297 aa)
LOC103179020Uncharacterized protein. (310 aa)
ENSCMIP00000042614Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (106 aa)
LOC103183483Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (287 aa)
sirt6Deacetylase sirtuin-type domain-containing protein. (363 aa)
btdCN hydrolase domain-containing protein. (527 aa)
sirt7Deacetylase sirtuin-type domain-containing protein. (396 aa)
LOC103180876Neutral ceramidase. (739 aa)
nit2CN hydrolase domain-containing protein. (284 aa)
faah2Amidase domain-containing protein. (628 aa)
naaaUncharacterized protein; Belongs to the acid ceramidase family. (314 aa)
hdac3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (425 aa)
hdac9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1117 aa)
sirt2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (321 aa)
amdhd2N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (412 aa)
hdac5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1097 aa)
wdyhv1Nt_Gln_amidase domain-containing protein. (177 aa)
sirt3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (366 aa)
catCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
faahAmidase domain-containing protein. (585 aa)
ntan1Protein NH2-terminal asparagine amidohydrolase-like protein. (310 aa)
LOC103191067ANK_REP_REGION domain-containing protein. (590 aa)
ENSCMIP00000025625Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (207 aa)
piglUncharacterized protein. (258 aa)
aspaUncharacterized protein. (372 aa)
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
Server load: low (36%) [HD]