(62 nodes) Cellular response to UV network (Callorhinchus milii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCMIP00000000371	Uncharacterized protein. (115 aa)
	ENSCMIP00000000678	Uncharacterized protein. (123 aa)
	sirt1	Deacetylase sirtuin-type domain-containing protein. (631 aa)
	ENSCMIP00000001045	UmuC domain-containing protein. (167 aa)
	ENSCMIP00000001059	UmuC domain-containing protein. (113 aa)
	Polk	Uncharacterized protein. (562 aa)
	ENSCMIP00000001520	HGTP_anticodon2 domain-containing protein. (106 aa)
	ENSCMIP00000002845	Uncharacterized protein. (147 aa)
	LOC103172902	Uncharacterized protein. (388 aa)
	ENSCMIP00000004369	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (106 aa)
	LOC103173288	Saposin B-type domain-containing protein. (449 aa)
	usp47	USP domain-containing protein; Belongs to the peptidase C19 family. (1405 aa)
	ENSCMIP00000005680	Uncharacterized protein. (162 aa)
	ENSCMIP00000006074	BTB domain-containing protein. (90 aa)
	LOC103174033	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (188 aa)
	tp53inp1	Tumor protein p53-inducible nuclear protein 1-like protein. (235 aa)
	ENSCMIP00000007514	UPF0029 domain-containing protein. (203 aa)
	Impact	UPF0029 domain-containing protein. (101 aa)
	ENSCMIP00000008542	Uncharacterized protein. (77 aa)
	ENSCMIP00000008550	Protein kinase domain-containing protein. (194 aa)
	tmem161a	Uncharacterized protein. (489 aa)
	ENSCMIP00000009949	Uncharacterized protein. (167 aa)
	dhx36	Uncharacterized protein. (944 aa)
	ENSCMIP00000010640	Protein kinase domain-containing protein. (131 aa)
	chek1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (480 aa)
	ep300	Uncharacterized protein. (2325 aa)
	zbtb1	Uncharacterized protein. (726 aa)
	parp1	Poly [ADP-ribose] polymerase. (1035 aa)
	atr	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2604 aa)
	casp9	Uncharacterized protein; Belongs to the peptidase C14A family. (408 aa)
	xpa	DNA repair protein complementing XP-A cells-like protein. (226 aa)
	crebbp	Uncharacterized protein. (2452 aa)
	rhbdd1	Rhomboid domain-containing protein. (308 aa)
	ercc4	ERCC4 domain-containing protein. (939 aa)
	ppid	Uncharacterized protein. (353 aa)
	eif2s1	S1 motif domain-containing protein. (329 aa)
	ENSCMIP00000023246	G_PROTEIN_RECEP_F1_2 domain-containing protein. (351 aa)
	opn5	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (340 aa)
	pold1	DNA polymerase. (1109 aa)
	cul4a	CULLIN_2 domain-containing protein; Belongs to the cullin family. (923 aa)
	stk11	Protein kinase domain-containing protein. (443 aa)
	ddb1	CPSF_A domain-containing protein. (1144 aa)
	Rhno1	Uncharacterized protein. (287 aa)
	opn3	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (399 aa)
	cul4b	CULLIN_2 domain-containing protein; Belongs to the cullin family. (755 aa)
	pbk	Lymphokine-activated killer T-cell-originated protein kinase-like protein. (326 aa)
	ENSCMIP00000035928	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (313 aa)
	pold3	Uncharacterized protein. (390 aa)
	ENSCMIP00000037345	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (227 aa)
	actr5	Uncharacterized protein; Belongs to the actin family. (463 aa)
	cops9	Myeloma overexpressed 2. (57 aa)
	ino80	Uncharacterized protein. (1413 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (765 aa)
	LOC103175017	Uncharacterized protein. (278 aa)
	LOC103176597	Hyaluronidase. (502 aa)
	bak1	Uncharacterized protein. (217 aa)
	bmf	Uncharacterized protein. (199 aa)
	polh	UmuC domain-containing protein. (719 aa)
	LOC103190153	Uncharacterized protein. (170 aa)
	LOC103190154	Uncharacterized protein. (174 aa)
	xpc	Uncharacterized protein. (956 aa)
	LOC103181832	Uncharacterized protein. (275 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000000678	ENSCMIP00000004369	ENSCMIP00000000678	ENSCMIP00000004369	Uncharacterized protein.	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.	0.874
ENSCMIP00000000678	actr5	ENSCMIP00000000678	ENSCMIP00000038240	Uncharacterized protein.	Uncharacterized protein; Belongs to the actin family.	0.944
ENSCMIP00000000678	ddb1	ENSCMIP00000000678	ENSCMIP00000026284	Uncharacterized protein.	CPSF_A domain-containing protein.	0.556
ENSCMIP00000000678	ercc4	ENSCMIP00000000678	ENSCMIP00000019357	Uncharacterized protein.	ERCC4 domain-containing protein.	0.414
ENSCMIP00000000678	xpa	ENSCMIP00000000678	ENSCMIP00000016243	Uncharacterized protein.	DNA repair protein complementing XP-A cells-like protein.	0.458
ENSCMIP00000000678	xpc	ENSCMIP00000000678	ENSCMIP00000047826	Uncharacterized protein.	Uncharacterized protein.	0.555
ENSCMIP00000001045	ENSCMIP00000001059	ENSCMIP00000001045	ENSCMIP00000001059	UmuC domain-containing protein.	UmuC domain-containing protein.	0.946
ENSCMIP00000001045	Polk	ENSCMIP00000001045	ENSCMIP00000001080	UmuC domain-containing protein.	Uncharacterized protein.	0.899
ENSCMIP00000001045	ercc4	ENSCMIP00000001045	ENSCMIP00000019357	UmuC domain-containing protein.	ERCC4 domain-containing protein.	0.443
ENSCMIP00000001045	pold1	ENSCMIP00000001045	ENSCMIP00000025107	UmuC domain-containing protein.	DNA polymerase.	0.746
ENSCMIP00000001045	polh	ENSCMIP00000001045	ENSCMIP00000044401	UmuC domain-containing protein.	UmuC domain-containing protein.	0.598
ENSCMIP00000001045	xpa	ENSCMIP00000001045	ENSCMIP00000016243	UmuC domain-containing protein.	DNA repair protein complementing XP-A cells-like protein.	0.571
ENSCMIP00000001059	ENSCMIP00000001045	ENSCMIP00000001059	ENSCMIP00000001045	UmuC domain-containing protein.	UmuC domain-containing protein.	0.946
ENSCMIP00000001059	Polk	ENSCMIP00000001059	ENSCMIP00000001080	UmuC domain-containing protein.	Uncharacterized protein.	0.900
ENSCMIP00000001059	ercc4	ENSCMIP00000001059	ENSCMIP00000019357	UmuC domain-containing protein.	ERCC4 domain-containing protein.	0.443
ENSCMIP00000001059	pold1	ENSCMIP00000001059	ENSCMIP00000025107	UmuC domain-containing protein.	DNA polymerase.	0.746
ENSCMIP00000001059	polh	ENSCMIP00000001059	ENSCMIP00000044401	UmuC domain-containing protein.	UmuC domain-containing protein.	0.697
ENSCMIP00000001059	xpa	ENSCMIP00000001059	ENSCMIP00000016243	UmuC domain-containing protein.	DNA repair protein complementing XP-A cells-like protein.	0.571
ENSCMIP00000001520	eif2s1	ENSCMIP00000001520	ENSCMIP00000021326	HGTP_anticodon2 domain-containing protein.	S1 motif domain-containing protein.	0.808
ENSCMIP00000002845	atr	ENSCMIP00000002845	ENSCMIP00000014069	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.833