(15 nodes) ATP-grasp fold, subdomain 1 network (Callorhinchus milii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	sucla2	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (459 aa)
	LOC103175934	Uncharacterized protein. (1289 aa)
	syn2	Uncharacterized protein. (471 aa)
	LOC103177882	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (451 aa)
	pc	Uncharacterized protein. (443 aa)
	LOC103186998	Uncharacterized protein. (661 aa)
	suclg2	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (439 aa)
	LOC103171706	Uncharacterized protein. (1072 aa)
	ENSCMIP00000005371	Synapsin_C domain-containing protein. (321 aa)
	syn3	Uncharacterized protein. (591 aa)
	rimkla	ATP-grasp domain-containing protein. (393 aa)
	cad	Uncharacterized protein. (2246 aa)
	gart	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (1016 aa)
	acacb	Uncharacterized protein. (2221 aa)
	cps1	Uncharacterized protein. (1504 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103171706	LOC103186998	ENSCMIP00000012822	ENSCMIP00000014683	Uncharacterized protein.	Uncharacterized protein.	0.525
LOC103171706	gart	ENSCMIP00000012822	ENSCMIP00000039298	Uncharacterized protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.887
LOC103171706	pc	ENSCMIP00000012822	ENSCMIP00000014949	Uncharacterized protein.	Uncharacterized protein.	0.501
LOC103177882	gart	ENSCMIP00000016632	ENSCMIP00000039298	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.621
LOC103177882	sucla2	ENSCMIP00000016632	ENSCMIP00000030227	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.901
LOC103177882	suclg2	ENSCMIP00000016632	ENSCMIP00000014033	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.941
LOC103186998	LOC103171706	ENSCMIP00000014683	ENSCMIP00000012822	Uncharacterized protein.	Uncharacterized protein.	0.525
LOC103186998	acacb	ENSCMIP00000014683	ENSCMIP00000036305	Uncharacterized protein.	Uncharacterized protein.	0.451
LOC103186998	pc	ENSCMIP00000014683	ENSCMIP00000014949	Uncharacterized protein.	Uncharacterized protein.	0.560
acacb	LOC103186998	ENSCMIP00000036305	ENSCMIP00000014683	Uncharacterized protein.	Uncharacterized protein.	0.451
acacb	gart	ENSCMIP00000036305	ENSCMIP00000039298	Uncharacterized protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.887
acacb	pc	ENSCMIP00000036305	ENSCMIP00000014949	Uncharacterized protein.	Uncharacterized protein.	0.463
cad	cps1	ENSCMIP00000042217	ENSCMIP00000033857	Uncharacterized protein.	Uncharacterized protein.	0.902
cad	gart	ENSCMIP00000042217	ENSCMIP00000039298	Uncharacterized protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.911
cps1	cad	ENSCMIP00000033857	ENSCMIP00000042217	Uncharacterized protein.	Uncharacterized protein.	0.902
cps1	gart	ENSCMIP00000033857	ENSCMIP00000039298	Uncharacterized protein.	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	0.911
gart	LOC103171706	ENSCMIP00000039298	ENSCMIP00000012822	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Uncharacterized protein.	0.887
gart	LOC103177882	ENSCMIP00000039298	ENSCMIP00000016632	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.621
gart	acacb	ENSCMIP00000039298	ENSCMIP00000036305	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Uncharacterized protein.	0.887
gart	cad	ENSCMIP00000039298	ENSCMIP00000042217	Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.	Uncharacterized protein.	0.911