78 items (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCMIP00000020274	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	gng12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	gnb4	WD_REPEATS_REGION domain-containing protein. (373 aa)
	LOC103191382	Uncharacterized protein. (182 aa)
	LOC103182089	Protein kinase domain-containing protein. (385 aa)
	ENSCMIP00000008016	AC_N domain-containing protein. (330 aa)
	gng7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	prkx	Uncharacterized protein. (289 aa)
	LOC103173116	AC_N domain-containing protein. (294 aa)
	ENSCMIP00000008939	PDE4_UCR domain-containing protein. (158 aa)
	ENSCMIP00000010316	WD_REPEATS_REGION domain-containing protein. (227 aa)
	LOC103182008	Phosphodiesterase. (849 aa)
	pde4a	Phosphodiesterase. (711 aa)
	plcb4	Uncharacterized protein. (178 aa)
	prkar1b	Uncharacterized protein. (390 aa)
	ENSCMIP00000012237	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (294 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC103171709	Phosphoinositide phospholipase C. (627 aa)
	camkk2	Protein kinase domain-containing protein. (546 aa)
	cdk5	Protein kinase domain-containing protein. (280 aa)
	snx19	PX domain-containing protein. (853 aa)
	ENSCMIP00000013988	Uncharacterized protein. (313 aa)
	ENSCMIP00000014007	Uncharacterized protein. (221 aa)
	LOC103182067	Uncharacterized protein. (368 aa)
	LOC103182068	Uncharacterized protein. (386 aa)
	plcb1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1196 aa)
	adcy1	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (961 aa)
	adcy2	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1099 aa)
	adcy9	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1345 aa)
	gng4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	LOC103182858	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	pdyn	Uncharacterized protein. (285 aa)
	pde1a	Phosphodiesterase. (585 aa)
	thap7	THAP-type domain-containing protein. (369 aa)
	pde1c	Phosphodiesterase. (748 aa)
	gnai1	Uncharacterized protein. (394 aa)
	ENSCMIP00000035562	Uncharacterized protein. (235 aa)
	ENSCMIP00000036828	Uncharacterized protein. (128 aa)
	adcy8	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1219 aa)
	V9L7J2_CALMI	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	plcb2	Phosphoinositide phospholipase C. (1047 aa)
	LOC103182452	Uncharacterized protein. (407 aa)
	LOC103186729	Serine/threonine-protein phosphatase. (309 aa)
	LOC103177669	THAP domain-containing protein 1-like protein. (207 aa)
	adcy5	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (273 aa)
	adcy7	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1069 aa)
	pla2g4a	Phospholipase A2. (769 aa)
	camk4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (456 aa)
	gng13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	gnai2	Uncharacterized protein. (365 aa)
	LOC103186353	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (145 aa)
	dclk1	Uncharacterized protein. (725 aa)
	prkar2a	cAMP-dependent protein kinase type II-alpha regulatory subunit-like protein. (409 aa)
	prkar1a	Uncharacterized protein. (324 aa)
	nbea	Uncharacterized protein. (2895 aa)
	LOC103177809	Uncharacterized protein. (78 aa)
	LOC103177810	Phosphodiesterase. (733 aa)
	prkaca	Uncharacterized protein; Belongs to the protein kinase superfamily. (348 aa)
	gnb5	WD_REPEATS_REGION domain-containing protein. (390 aa)
	camkk1	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (449 aa)
	LOC103189115	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	LOC103175737	Uncharacterized protein. (349 aa)
	ENSCMIP00000048683	Uncharacterized protein. (101 aa)
	gng2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	LOC103191092	PH_14 domain-containing protein. (290 aa)
	lrba	Uncharacterized protein. (2844 aa)
	ENSCMIP00000022916	Uncharacterized protein. (63 aa)
	gna14	Uncharacterized protein. (357 aa)
	gnaq	Uncharacterized protein. (335 aa)
	ENSCMIP00000021889	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	ppp1r1b	Uncharacterized protein. (212 aa)
	gnb1	WD_REPEATS_REGION domain-containing protein. (340 aa)
	ppp2r1a	Uncharacterized protein. (636 aa)
	ENSCMIP00000017983	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	prkacb	Uncharacterized protein; Belongs to the protein kinase superfamily. (397 aa)
	ENSCMIP00000019096	Uncharacterized protein. (383 aa)
	ENSCMIP00000019259	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
	prkar2b	Uncharacterized protein. (395 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000008016	ENSCMIP00000012237	ENSCMIP00000008016	ENSCMIP00000012237	AC_N domain-containing protein.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.900
ENSCMIP00000008016	ENSCMIP00000014007	ENSCMIP00000008016	ENSCMIP00000014007	AC_N domain-containing protein.	Uncharacterized protein.	0.475
ENSCMIP00000008016	ENSCMIP00000017983	ENSCMIP00000008016	ENSCMIP00000017983	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.480
ENSCMIP00000008016	LOC103186353	ENSCMIP00000008016	ENSCMIP00000043140	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.469
ENSCMIP00000008016	LOC103189115	ENSCMIP00000008016	ENSCMIP00000047338	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.477
ENSCMIP00000008016	V9L7J2_CALMI	ENSCMIP00000008016	ENSCMIP00000021614	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.487
ENSCMIP00000008016	adcy1	ENSCMIP00000008016	ENSCMIP00000015428	AC_N domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.694
ENSCMIP00000008016	adcy2	ENSCMIP00000008016	ENSCMIP00000016065	AC_N domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.652
ENSCMIP00000008016	adcy5	ENSCMIP00000008016	ENSCMIP00000040926	AC_N domain-containing protein.	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.899
ENSCMIP00000008016	adcy7	ENSCMIP00000008016	ENSCMIP00000041196	AC_N domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.652
ENSCMIP00000008016	adcy8	ENSCMIP00000008016	ENSCMIP00000037276	AC_N domain-containing protein.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.476
ENSCMIP00000008016	adcy9	ENSCMIP00000008016	ENSCMIP00000016610	AC_N domain-containing protein.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.585
ENSCMIP00000008016	gnb5	ENSCMIP00000008016	ENSCMIP00000047205	AC_N domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.505
ENSCMIP00000008016	gng13	ENSCMIP00000008016	ENSCMIP00000042521	AC_N domain-containing protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.496
ENSCMIP00000008016	gng2	ENSCMIP00000008016	ENSCMIP00000025713	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.419
ENSCMIP00000008016	gng4	ENSCMIP00000008016	ENSCMIP00000026189	AC_N domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.419
ENSCMIP00000008939	pde1a	ENSCMIP00000008939	ENSCMIP00000033539	PDE4_UCR domain-containing protein.	Phosphodiesterase.	0.704
ENSCMIP00000008939	pde1c	ENSCMIP00000008939	ENSCMIP00000035139	PDE4_UCR domain-containing protein.	Phosphodiesterase.	0.515
ENSCMIP00000008939	prkaca	ENSCMIP00000008939	ENSCMIP00000047063	PDE4_UCR domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.530
ENSCMIP00000008939	prkacb	ENSCMIP00000008939	ENSCMIP00000018848	PDE4_UCR domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.530