46 items (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC103171836	HMG box domain-containing protein. (101 aa)
	gng12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	gnb4	WD_REPEATS_REGION domain-containing protein. (373 aa)
	LOC103186967	Serine/threonine-protein phosphatase. (523 aa)
	ppp3cb	Serine/threonine-protein phosphatase. (513 aa)
	gng7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ENSCMIP00000010316	WD_REPEATS_REGION domain-containing protein. (227 aa)
	tcf7	HMG box domain-containing protein. (351 aa)
	plcb1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1196 aa)
	ENSCMIP00000015333	HMG box domain-containing protein. (304 aa)
	gnb1	WD_REPEATS_REGION domain-containing protein. (340 aa)
	ENSCMIP00000017983	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	nfatc1	RHD domain-containing protein. (974 aa)
	ENSCMIP00000019259	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
	ENSCMIP00000020274	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	ppp3cc	Serine/threonine-protein phosphatase. (491 aa)
	fzd6	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (669 aa)
	V9L7J2_CALMI	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	ENSCMIP00000021889	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	ctnnb1	Uncharacterized protein. (784 aa)
	tcf7l2	HMG box domain-containing protein. (600 aa)
	nlk	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (459 aa)
	gng2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	gng4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
	pde6h	Phosphodiesterase 6H. (81 aa)
	LOC103182858	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (67 aa)
	map3k20	Mitogen-activated protein kinase kinase kinase MLT-like protein. (851 aa)
	fzd3	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (673 aa)
	pde6b	Phosphodiesterase. (858 aa)
	Fzd4	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (526 aa)
	ENSCMIP00000033705	Uncharacterized protein. (79 aa)
	nfat5	RHD domain-containing protein. (1455 aa)
	LOC103190568	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
	ppp3ca	Serine/threonine-protein phosphatase. (531 aa)
	map3k7	Protein kinase domain-containing protein. (614 aa)
	plcb2	Phosphoinositide phospholipase C. (1047 aa)
	LOC103178866	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	gng13	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
	LOC103186353	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (145 aa)
	pde6c	Phosphodiesterase. (854 aa)
	LOC103175521	Uncharacterized protein. (118 aa)
	gnb5	WD_REPEATS_REGION domain-containing protein. (390 aa)
	LOC103189115	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	pde6a	Phosphodiesterase. (855 aa)
	wdr92	WD_REPEATS_REGION domain-containing protein. (358 aa)
	ppp3r1	Uncharacterized protein. (187 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000010316	ENSCMIP00000017983	ENSCMIP00000010316	ENSCMIP00000017983	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.777
ENSCMIP00000010316	ENSCMIP00000019259	ENSCMIP00000010316	ENSCMIP00000019259	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.605
ENSCMIP00000010316	ENSCMIP00000020274	ENSCMIP00000010316	ENSCMIP00000020274	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.605
ENSCMIP00000010316	ENSCMIP00000021889	ENSCMIP00000010316	ENSCMIP00000021889	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.605
ENSCMIP00000010316	Fzd4	ENSCMIP00000010316	ENSCMIP00000032597	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.484
ENSCMIP00000010316	LOC103175521	ENSCMIP00000010316	ENSCMIP00000046486	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.427
ENSCMIP00000010316	LOC103182858	ENSCMIP00000010316	ENSCMIP00000028245	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.605
ENSCMIP00000010316	LOC103186353	ENSCMIP00000010316	ENSCMIP00000043140	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.893
ENSCMIP00000010316	LOC103189115	ENSCMIP00000010316	ENSCMIP00000047338	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.794
ENSCMIP00000010316	V9L7J2_CALMI	ENSCMIP00000010316	ENSCMIP00000021614	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.769
ENSCMIP00000010316	fzd3	ENSCMIP00000010316	ENSCMIP00000030652	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.453
ENSCMIP00000010316	fzd6	ENSCMIP00000010316	ENSCMIP00000021531	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.453
ENSCMIP00000010316	gnb5	ENSCMIP00000010316	ENSCMIP00000047205	WD_REPEATS_REGION domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.471
ENSCMIP00000010316	gng12	ENSCMIP00000010316	ENSCMIP00000001196	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.605
ENSCMIP00000010316	gng13	ENSCMIP00000010316	ENSCMIP00000042521	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13.	0.836
ENSCMIP00000010316	gng2	ENSCMIP00000010316	ENSCMIP00000025713	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.759
ENSCMIP00000010316	gng4	ENSCMIP00000010316	ENSCMIP00000026189	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.759
ENSCMIP00000010316	gng7	ENSCMIP00000010316	ENSCMIP00000008316	WD_REPEATS_REGION domain-containing protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.605
ENSCMIP00000010316	pde6h	ENSCMIP00000010316	ENSCMIP00000027910	WD_REPEATS_REGION domain-containing protein.	Phosphodiesterase 6H.	0.409
ENSCMIP00000015333	LOC103171836	ENSCMIP00000015333	ENSCMIP00000000345	HMG box domain-containing protein.	HMG box domain-containing protein.	0.619