32 items (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	polr2d	RPOL4c domain-containing protein. (170 aa)
	rngtt	Polynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (601 aa)
	gtf2h5	General transcription factor IIH subunit 5. (71 aa)
	polr2j	RNA_pol_L_2 domain-containing protein. (115 aa)
	gtf2f2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (288 aa)
	LOC103174512	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (115 aa)
	LOC103174237	HELICc2 domain-containing protein. (108 aa)
	LOC103174263	Uncharacterized protein. (177 aa)
	Rnmt	mRNA cap 0 methyltransferase domain-containing protein. (338 aa)
	polr2f	Uncharacterized protein. (98 aa)
	gtf2h1	Uncharacterized protein. (592 aa)
	LOC103187820	Uncharacterized protein. (175 aa)
	polr2h	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	ncbp2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
	ENSCMIP00000018780	Uncharacterized protein. (152 aa)
	gtf2h2	General transcription factor IIH subunit. (398 aa)
	ercc3	Uncharacterized protein. (783 aa)
	ncbp1	MIF4G domain-containing protein. (775 aa)
	ccnh	CYCLIN domain-containing protein; Belongs to the cyclin family. (340 aa)
	supt5h	Transcription elongation factor SPT5. (1103 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (243 aa)
	polr2c	RPOLD domain-containing protein. (295 aa)
	polr2k	Uncharacterized protein. (63 aa)
	polr2g	Uncharacterized protein. (152 aa)
	ENSCMIP00000002936	Uncharacterized protein. (66 aa)
	ENSCMIP00000004147	RNA_pol_Rpb1_1 domain-containing protein. (182 aa)
	LOC103173973	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (183 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
	polr2e	Uncharacterized protein. (218 aa)
	ENSCMIP00000042955	TYR_PHOSPHATASE_2 domain-containing protein. (181 aa)
	polr2b	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1208 aa)
	gtf2h3	Uncharacterized protein. (320 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCMIP00000002936	ENSCMIP00000004147	ENSCMIP00000002936	ENSCMIP00000004147	Uncharacterized protein.	RNA_pol_Rpb1_1 domain-containing protein.	0.931
ENSCMIP00000002936	ENSCMIP00000018780	ENSCMIP00000002936	ENSCMIP00000018780	Uncharacterized protein.	Uncharacterized protein.	0.969
ENSCMIP00000002936	ENSCMIP00000042955	ENSCMIP00000002936	ENSCMIP00000042955	Uncharacterized protein.	TYR_PHOSPHATASE_2 domain-containing protein.	0.616
ENSCMIP00000002936	LOC103173973	ENSCMIP00000002936	ENSCMIP00000005894	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.929
ENSCMIP00000002936	LOC103174237	ENSCMIP00000002936	ENSCMIP00000001786	Uncharacterized protein.	HELICc2 domain-containing protein.	0.971
ENSCMIP00000002936	LOC103174263	ENSCMIP00000002936	ENSCMIP00000001946	Uncharacterized protein.	Uncharacterized protein.	0.999
ENSCMIP00000002936	LOC103174512	ENSCMIP00000002936	ENSCMIP00000000612	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.929
ENSCMIP00000002936	LOC103187820	ENSCMIP00000002936	ENSCMIP00000023686	Uncharacterized protein.	Uncharacterized protein.	0.616
ENSCMIP00000002936	Rnmt	ENSCMIP00000002936	ENSCMIP00000046948	Uncharacterized protein.	mRNA cap 0 methyltransferase domain-containing protein.	0.837
ENSCMIP00000002936	ccnh	ENSCMIP00000002936	ENSCMIP00000015958	Uncharacterized protein.	CYCLIN domain-containing protein; Belongs to the cyclin family.	0.937
ENSCMIP00000002936	ercc3	ENSCMIP00000002936	ENSCMIP00000016348	Uncharacterized protein.	Uncharacterized protein.	0.985
ENSCMIP00000002936	gtf2f1	ENSCMIP00000002936	ENSCMIP00000009076	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.929
ENSCMIP00000002936	gtf2f2	ENSCMIP00000002936	ENSCMIP00000027489	Uncharacterized protein.	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity.	0.992
ENSCMIP00000002936	gtf2h1	ENSCMIP00000002936	ENSCMIP00000025830	Uncharacterized protein.	Uncharacterized protein.	0.968
ENSCMIP00000002936	gtf2h2	ENSCMIP00000002936	ENSCMIP00000017953	Uncharacterized protein.	General transcription factor IIH subunit.	0.983
ENSCMIP00000002936	gtf2h3	ENSCMIP00000002936	ENSCMIP00000033644	Uncharacterized protein.	Uncharacterized protein.	0.983
ENSCMIP00000002936	gtf2h5	ENSCMIP00000002936	ENSCMIP00000029167	Uncharacterized protein.	General transcription factor IIH subunit 5.	0.867
ENSCMIP00000002936	mnat1	ENSCMIP00000002936	ENSCMIP00000006614	Uncharacterized protein.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.982
ENSCMIP00000002936	ncbp2	ENSCMIP00000002936	ENSCMIP00000019578	Uncharacterized protein.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.832
ENSCMIP00000002936	polr2b	ENSCMIP00000002936	ENSCMIP00000038862	Uncharacterized protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999