STRINGSTRING
polb polb plk1 plk1 lmnb1 lmnb1 upf2 upf2 plk3 plk3 smc5 smc5 orc4 orc4 lmnb2 lmnb2 LOC103183812 LOC103183812 LOC103186049 LOC103186049 dhcr24 dhcr24 pkn2 pkn2 taf10 taf10 LOC103177258 LOC103177258 sumo1 sumo1 nup85 nup85 sumo2 sumo2 canx canx sec13 sec13 cdk1 cdk1 plk2 plk2 smc3 smc3 nmd3 nmd3 ranbp2 ranbp2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (340 aa)
plk1Serine/threonine-protein kinase PLK. (610 aa)
lmnb1Uncharacterized protein; Belongs to the intermediate filament family. (611 aa)
upf2Uncharacterized protein. (1225 aa)
plk3Serine/threonine-protein kinase PLK. (634 aa)
smc5AAA_23 domain-containing protein. (1049 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
lmnb2Uncharacterized protein; Belongs to the intermediate filament family. (626 aa)
LOC103183812Small ubiquitin-related modifier. (107 aa)
LOC103186049Small ubiquitin-related modifier. (124 aa)
dhcr24FAD-binding PCMH-type domain-containing protein. (516 aa)
pkn2Uncharacterized protein. (973 aa)
taf10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (186 aa)
LOC103177258Calnexin. (575 aa)
sumo1Small ubiquitin-related modifier. (111 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (701 aa)
sumo2Small ubiquitin-related modifier. (113 aa)
canxCalnexin. (613 aa)
sec13WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (320 aa)
cdk1Cyclin-dependent kinase 1-like protein; Belongs to the protein kinase superfamily. (301 aa)
plk2Serine/threonine-protein kinase PLK. (668 aa)
smc3Structural maintenance of chromosomes protein. (1191 aa)
nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (506 aa)
ranbp2Uncharacterized protein. (3000 aa)
Your Current Organism:
Callorhinchus milii
NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe
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