24 items (Callorhinchus milii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dkk1	Dickkopf_N domain-containing protein. (245 aa)
	klf2	Uncharacterized protein. (452 aa)
	grb2	Uncharacterized protein. (246 aa)
	lamc1	Uncharacterized protein. (1498 aa)
	amot	Angiomotin_C domain-containing protein. (859 aa)
	gsk3b	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa)
	sox17	Uncharacterized protein. (414 aa)
	lama5	Uncharacterized protein. (3180 aa)
	ezr	FERM domain-containing protein. (604 aa)
	pdgfra	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1102 aa)
	wwtr1	Uncharacterized protein. (438 aa)
	gata6	Transcription factor GATA-6-like protein. (509 aa)
	fgfr3	Fibroblast growth factor receptor. (776 aa)
	tfcp2l1	Uncharacterized protein. (488 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (156 aa)
	cdx2	Homeobox domain-containing protein. (283 aa)
	id2	DNA-binding protein inhibitor ID-2-like protein. (141 aa)
	lats1	Uncharacterized protein. (1168 aa)
	nf2	FERM domain-containing protein. (599 aa)
	klf4	Uncharacterized protein. (415 aa)
	fgfr2	Fibroblast growth factor receptor. (841 aa)
	yap1	WW domain-containing protein. (522 aa)
	tbx3	TBX domain-containing protein. (441 aa)
	acvr2b	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)

Your Current Organism:

Callorhinchus milii

NCBI taxonomy Id: 7868
Other names: Australian ghost shark, C. milii, elephant fish, elephant shark, ghost shark, makorepe, plownose chimaera, reperepe

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acvr2b	dkk1	ENSCMIP00000006465	ENSCMIP00000046769	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Dickkopf_N domain-containing protein.	0.543
amot	ezr	ENSCMIP00000040143	ENSCMIP00000029518	Angiomotin_C domain-containing protein.	FERM domain-containing protein.	0.499
amot	lats1	ENSCMIP00000040143	ENSCMIP00000017802	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.866
amot	nf2	ENSCMIP00000040143	ENSCMIP00000017566	Angiomotin_C domain-containing protein.	FERM domain-containing protein.	0.740
amot	wwtr1	ENSCMIP00000040143	ENSCMIP00000023714	Angiomotin_C domain-containing protein.	Uncharacterized protein.	0.759
amot	yap1	ENSCMIP00000040143	ENSCMIP00000011714	Angiomotin_C domain-containing protein.	WW domain-containing protein.	0.858
cdx2	gata6	ENSCMIP00000019667	ENSCMIP00000023045	Homeobox domain-containing protein.	Transcription factor GATA-6-like protein.	0.573
cdx2	sox17	ENSCMIP00000019667	ENSCMIP00000038510	Homeobox domain-containing protein.	Uncharacterized protein.	0.557
dkk1	acvr2b	ENSCMIP00000046769	ENSCMIP00000006465	Dickkopf_N domain-containing protein.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.543
ezr	amot	ENSCMIP00000029518	ENSCMIP00000040143	FERM domain-containing protein.	Angiomotin_C domain-containing protein.	0.499
ezr	lats1	ENSCMIP00000029518	ENSCMIP00000017802	FERM domain-containing protein.	Uncharacterized protein.	0.455
fgf2	fgfr2	ENSCMIP00000020541	ENSCMIP00000015209	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.855
fgf2	fgfr3	ENSCMIP00000020541	ENSCMIP00000022472	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.522
fgf2	grb2	ENSCMIP00000020541	ENSCMIP00000043216	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein.	0.416
fgf2	pdgfra	ENSCMIP00000020541	ENSCMIP00000029195	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.758
fgfr2	fgf2	ENSCMIP00000015209	ENSCMIP00000020541	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.855
fgfr2	grb2	ENSCMIP00000015209	ENSCMIP00000043216	Fibroblast growth factor receptor.	Uncharacterized protein.	0.961
fgfr2	pdgfra	ENSCMIP00000015209	ENSCMIP00000029195	Fibroblast growth factor receptor.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.930
fgfr3	fgf2	ENSCMIP00000022472	ENSCMIP00000020541	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.522
fgfr3	grb2	ENSCMIP00000022472	ENSCMIP00000043216	Fibroblast growth factor receptor.	Uncharacterized protein.	0.669