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| | UMPS | Uridine monophosphate synthetase. (290 aa) |
| | NT5C3B | 5'-nucleotidase, cytosolic IIIB. (220 aa) |
| | LOC106702268 | Uncharacterized protein. (107 aa) |
| | H2ZTM4_LATCH | Uncharacterized protein. (163 aa) |
| | LOC102351310 | Adenine phosphoribosyltransferase. (119 aa) |
| | LOC102357684 | Zgc:110789. (351 aa) |
| | SLC28A3 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (522 aa) |
| | AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (229 aa) |
| | DALRD3 | DALR anticodon binding domain containing 3. (405 aa) |
| | LOC102347240 | Pribosyltran_N domain-containing protein. (322 aa) |
| | LOC102352017 | Zgc:174895. (223 aa) |
| | ADSS1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (449 aa) |
| | LOC102356827 | Uncharacterized protein. (205 aa) |
| | QPRT | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (324 aa) |
| | ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (500 aa) |
| | AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (823 aa) |
| | UPP1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (313 aa) |
| | NT5C3A | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (284 aa) |
| | LOC102357063 | Uncharacterized protein. (367 aa) |
| | DTYMK | Deoxythymidylate kinase. (189 aa) |
| | DPYS | Dihydropyrimidinase. (514 aa) |
| | CRMP1 | Collapsin response mediator protein 1. (659 aa) |
| | LOC102355337 | Zgc:110540. (270 aa) |
| | IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (524 aa) |
| | ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase. (594 aa) |
| | LOC102354234 | Phosphodiesterase. (711 aa) |
| | PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (444 aa) |
| | NIT2 | Nitrilase family member 2. (283 aa) |
| | NAMPT | Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (492 aa) |
| | DGUOK | Deoxyguanosine kinase. (286 aa) |
| | LOC106704948 | Uncharacterized protein; Belongs to the adenylate kinase family. (552 aa) |
| | AK3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa) |
| | LOC102362277 | Uncharacterized protein; Belongs to the 5'-nucleotidase family. (541 aa) |
| | QRICH1 | Glutamine rich 1. (779 aa) |
| | GMPR2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (350 aa) |
| | PAICS | AIRC domain-containing protein. (1029 aa) |
| | CYB5RL | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (312 aa) |
| | H3A831_LATCH | Aldehyde oxidase 5. (1307 aa) |
| | NMNAT1 | Nicotinamide-nucleotide adenylyltransferase. (286 aa) |
| | H3A8S5_LATCH | Nicotinate phosphoribosyltransferase. (581 aa) |
| | LOC102350392 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (214 aa) |
| | PDK2 | Protein-serine/threonine kinase. (540 aa) |
| | NME6 | Nucleoside diphosphate kinase. (188 aa) |
| | NME1 | Nucleoside diphosphate kinase. (172 aa) |
| | LOC102357966 | Si:dkey-4e7.3. (318 aa) |
| | SIRT3 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) |
| | NT5C | 5', 3'-nucleotidase, cytosolic. (199 aa) |
| | GMPR | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (345 aa) |
| | UCK2 | Uridine-cytidine kinase 2. (180 aa) |
| | ANKRD33B | ANK_REP_REGION domain-containing protein. (373 aa) |
| | H3ACR0_LATCH | Uncharacterized protein. (151 aa) |
| | NMNAT3 | Nicotinamide-nucleotide adenylyltransferase. (290 aa) |
| | SLC23A2 | Solute carrier family 23 member 2. (616 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (448 aa) |
| | MBOAT1 | Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (430 aa) |
| | SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (310 aa) |
| | NMNAT2 | Nicotinamide nucleotide adenylyltransferase 2. (202 aa) |
| | DPYSL3 | Dihydropyrimidinase like 3. (663 aa) |
| | GMPS | Guanine monophosphate synthase. (683 aa) |
| | LOC102349693 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (293 aa) |
| | SIRT6 | Sirtuin 6. (375 aa) |
| | AK5 | Adenylate kinase 5; Belongs to the adenylate kinase family. (296 aa) |
| | CYB5D1 | Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family. (215 aa) |
| | RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa) |
| | OXNAD1 | Oxidoreductase NAD binding domain containing 1. (315 aa) |
| | IMPDH1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (515 aa) |
| | ISOC2 | Isochorismatase domain containing 2. (213 aa) |
| | SIRT7 | Sirtuin 7. (413 aa) |
| | ALLC | Allantoicase. (395 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (469 aa) |
| | NUDT15 | Nudix hydrolase 15; Belongs to the Nudix hydrolase family. (165 aa) |
| | PDE1C | Phosphodiesterase. (440 aa) |
| | NT5DC4 | 5'-nucleotidase domain containing 4. (475 aa) |
| | PPA2 | Pyrophosphatase (inorganic) 2. (313 aa) |
| | PDE7B | Phosphodiesterase. (421 aa) |
| | H3AMS8_LATCH | Uncharacterized protein; Belongs to the adenylate kinase family. (171 aa) |
| | AK9 | Adenylate kinase 9. (1928 aa) |
| | H3ANZ2_LATCH | Uncharacterized protein. (440 aa) |
| | CMPK1 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (213 aa) |
| | PDE3B | Phosphodiesterase. (1104 aa) |
| | ENTPD6 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (425 aa) |
| | NT5M | 5',3'-nucleotidase, mitochondrial. (242 aa) |
| | PRPSAP2 | Phosphoribosyl pyrophosphate synthetase associated protein 2. (357 aa) |
| | DPYSL4 | Dihydropyrimidinase like 4. (692 aa) |
| | ADSS2 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (460 aa) |
| | DCK | Deoxycytidine kinase. (263 aa) |
| | SLC23A1 | Solute carrier family 23 member 1. (590 aa) |
| | AK6 | Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (174 aa) |
| | GUK1 | Guanylate kinase 1. (210 aa) |
| | NMRK1 | Nicotinamide riboside kinase 1. (212 aa) |
| | NADK2 | NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor. (427 aa) |
| | GOLT1B | Golgi transport 1B. (138 aa) |
| | DPYD | Pyr_redox_2 domain-containing protein. (333 aa) |
| | CYB5R4 | Cytochrome b5 reductase 4. (519 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (389 aa) |
| | GDA | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (411 aa) |
| | LOC102365706 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa) |
| | ITPA | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (192 aa) |
| | H3AUJ0_LATCH | G_PROTEIN_RECEP_F1_2 domain-containing protein. (341 aa) |
| | MANEA | Mannosidase endo-alpha. (446 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (528 aa) |
| | NT5C1A | 5'-nucleotidase, cytosolic IA. (371 aa) |
| | TYMP | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (474 aa) |
| | GPR143 | G protein-coupled receptor 143. (413 aa) |
| | NME3 | NME/NM23 nucleoside diphosphate kinase 3; Belongs to the NDK family. (131 aa) |
| | ENTPD4 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (481 aa) |
| | H3B0V9_LATCH | Phosphodiesterase. (538 aa) |
| | LOC102367147 | MOSC domain-containing protein. (333 aa) |
| | H3B2A9_LATCH | Uncharacterized protein. (97 aa) |
| | PDE8B | Phosphodiesterase. (778 aa) |
| | NME7 | Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa) |
| | ADA | A_deaminase domain-containing protein. (132 aa) |
| | DCTD | dCMP deaminase. (202 aa) |
| | UPB1 | Beta-ureidopropionase 1. (390 aa) |
| | CCDC9 | Coiled-coil domain containing 9. (396 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (517 aa) |
| | NADSYN1 | Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (706 aa) |
| | NUDT12 | Nudix hydrolase 12. (460 aa) |
| | ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2b; Belongs to the GDA1/CD39 NTPase family. (500 aa) |
| | TK1 | Thymidine kinase. (239 aa) |
| | CYP4F8 | Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (356 aa) |
| | CANT1 | Calcium activated nucleotidase 1. (400 aa) |
| | PRPSAP1 | Phosphoribosyl pyrophosphate synthetase associated protein 1. (290 aa) |
| | HDDC3 | HD domain containing 3. (179 aa) |
| | SLC28A1 | Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (599 aa) |
| | PDE6C | Phosphodiesterase. (838 aa) |
| | CYB5A | Cytochrome b5 type A; Belongs to the cytochrome b5 family. (137 aa) |
| | H3BAZ9_LATCH | Adenylate kinase 5, like; Belongs to the adenylate kinase family. (437 aa) |
| | LOC102362571 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (311 aa) |
| | NTPCR | Nucleoside-triphosphatase, cancer-related. (196 aa) |
| | HPRT1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (180 aa) |
| | UCK1 | Uridine-cytidine kinase; Belongs to the uridine kinase family. (270 aa) |
| | LOC102345276 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (405 aa) |
| | DPYSL2 | Dihydropyrimidinase like 2. (677 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (507 aa) |
| | AMPD3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (773 aa) |
| | AK7 | Adenylate kinase 7. (711 aa) |
| | SIRT4 | NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (315 aa) |
| | ENTPD5 | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (431 aa) |
| | AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (706 aa) |
| | ADAL | Adenosine deaminase like. (358 aa) |
| | NADK | NAD kinase. (308 aa) |
| | M3XGG2_LATCH | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (141 aa) |
| | LOC102360643 | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (306 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (309 aa) |
| | LOC102352541 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (286 aa) |
| | URAD | Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase. (175 aa) |
| | ADK | Adenosine kinase. (302 aa) |
| | PDE8A | Phosphodiesterase. (808 aa) |
| | CYB5B | Cytochrome b5 type B; Belongs to the cytochrome b5 family. (146 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (145 aa) |
| | PDE1A | Phosphodiesterase. (543 aa) |
| | M3XK43_LATCH | Zgc:136858. (599 aa) |
| | AK2 | Adenylate kinase 2; Belongs to the adenylate kinase family. (217 aa) |
| | LOC102365245 | Zgc:103559. (464 aa) |
| | ISOC1 | Isochorismatase domain containing 1. (289 aa) |
