(11 nodes) Growth hormone receptor signaling pathway via JAK-STAT, and Regulation of IFNG signaling network (Latimeria chalumnae)

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second shell of interactors

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Predicted Interactions

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textmining

co-expression

protein homology

Your Input:
	LOC102348150	Signal transducer and activator of transcription. (786 aa)
	IFNAR1	Uncharacterized protein. (548 aa)
	LOC102356003	SH2 domain-containing protein. (170 aa)
	JAK2	Tyrosine-protein kinase. (1152 aa)
	STAT1	Signal transducer and activator of transcription. (1179 aa)
	JAK1	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (613 aa)
	SOCS1	Suppressor of cytokine signaling 1a. (190 aa)
	LOC102360670	Uncharacterized protein. (209 aa)
	STAT3	Signal transducer and activator of transcription. (763 aa)
	SOCS3	Suppressor of cytokine signaling 3. (205 aa)
	STAT2	Signal transducer and activator of transcription. (765 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IFNAR1	JAK1	ENSLACP00000002973	ENSLACP00000007727	Uncharacterized protein.	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.997
IFNAR1	JAK2	ENSLACP00000002973	ENSLACP00000006953	Uncharacterized protein.	Tyrosine-protein kinase.	0.974
IFNAR1	LOC102348150	ENSLACP00000002973	ENSLACP00000002957	Uncharacterized protein.	Signal transducer and activator of transcription.	0.704
IFNAR1	LOC102356003	ENSLACP00000002973	ENSLACP00000003584	Uncharacterized protein.	SH2 domain-containing protein.	0.930
IFNAR1	LOC102360670	ENSLACP00000002973	ENSLACP00000012878	Uncharacterized protein.	Uncharacterized protein.	0.558
IFNAR1	SOCS1	ENSLACP00000002973	ENSLACP00000009341	Uncharacterized protein.	Suppressor of cytokine signaling 1a.	0.894
IFNAR1	SOCS3	ENSLACP00000002973	ENSLACP00000019685	Uncharacterized protein.	Suppressor of cytokine signaling 3.	0.659
IFNAR1	STAT1	ENSLACP00000002973	ENSLACP00000007692	Uncharacterized protein.	Signal transducer and activator of transcription.	0.924
IFNAR1	STAT2	ENSLACP00000002973	ENSLACP00000021655	Uncharacterized protein.	Signal transducer and activator of transcription.	0.924
IFNAR1	STAT3	ENSLACP00000002973	ENSLACP00000013656	Uncharacterized protein.	Signal transducer and activator of transcription.	0.832
JAK1	IFNAR1	ENSLACP00000007727	ENSLACP00000002973	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.997
JAK1	JAK2	ENSLACP00000007727	ENSLACP00000006953	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.967
JAK1	LOC102348150	ENSLACP00000007727	ENSLACP00000002957	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription.	0.864
JAK1	LOC102356003	ENSLACP00000007727	ENSLACP00000003584	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	SH2 domain-containing protein.	0.900
JAK1	LOC102360670	ENSLACP00000007727	ENSLACP00000012878	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.975
JAK1	SOCS1	ENSLACP00000007727	ENSLACP00000009341	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Suppressor of cytokine signaling 1a.	0.914
JAK1	SOCS3	ENSLACP00000007727	ENSLACP00000019685	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Suppressor of cytokine signaling 3.	0.984
JAK1	STAT1	ENSLACP00000007727	ENSLACP00000007692	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription.	0.945
JAK1	STAT2	ENSLACP00000007727	ENSLACP00000021655	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription.	0.917
JAK1	STAT3	ENSLACP00000007727	ENSLACP00000013656	Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Signal transducer and activator of transcription.	0.915