(13 nodes) SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion, and Other semaphorin interactions network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZSG0_LATCH	Sema domain-containing protein. (212 aa)
	PLXNA3-2	Plexin A3. (1193 aa)
	SEMA6B	Sema domain-containing protein; Belongs to the semaphorin family. (911 aa)
	PLXNA3	Sema domain-containing protein. (698 aa)
	LOC102347877	Uncharacterized protein. (1033 aa)
	PLXND1	Plexin D1. (1875 aa)
	H3AY29_LATCH	Uncharacterized protein. (534 aa)
	FARP1	FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1031 aa)
	SEMA4A	Sema domain-containing protein; Belongs to the semaphorin family. (758 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (635 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (739 aa)
	SEMA3B	Semaphorin 3B; Belongs to the semaphorin family. (767 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (928 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FARP1	LOC102347877	ENSLACP00000015415	ENSLACP00000012157	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Uncharacterized protein.	0.401
FARP1	NRP1	ENSLACP00000015415	ENSLACP00000023533	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Neuropilin; Belongs to the neuropilin family.	0.635
FARP1	PLXNA3	ENSLACP00000015415	ENSLACP00000006959	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Sema domain-containing protein.	0.401
FARP1	PLXNA3-2	ENSLACP00000015415	ENSLACP00000002847	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Plexin A3.	0.401
FARP1	PLXND1	ENSLACP00000015415	ENSLACP00000013783	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Plexin D1.	0.444
FARP1	SEMA3A	ENSLACP00000015415	ENSLACP00000015743	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Semaphorin 3A; Belongs to the semaphorin family.	0.505
FARP1	SEMA3B	ENSLACP00000015415	ENSLACP00000018405	FERM, ARH/RhoGEF and pleckstrin domain protein 1.	Semaphorin 3B; Belongs to the semaphorin family.	0.505
H2ZSG0_LATCH	H3AY29_LATCH	ENSLACP00000000331	ENSLACP00000014550	Sema domain-containing protein.	Uncharacterized protein.	0.899
H2ZSG0_LATCH	LOC102347877	ENSLACP00000000331	ENSLACP00000012157	Sema domain-containing protein.	Uncharacterized protein.	0.454
H2ZSG0_LATCH	NRP1	ENSLACP00000000331	ENSLACP00000023533	Sema domain-containing protein.	Neuropilin; Belongs to the neuropilin family.	0.596
H2ZSG0_LATCH	PLXNA3	ENSLACP00000000331	ENSLACP00000006959	Sema domain-containing protein.	Sema domain-containing protein.	0.454
H2ZSG0_LATCH	PLXNA3-2	ENSLACP00000000331	ENSLACP00000002847	Sema domain-containing protein.	Plexin A3.	0.454
H2ZSG0_LATCH	PLXND1	ENSLACP00000000331	ENSLACP00000013783	Sema domain-containing protein.	Plexin D1.	0.454
H3AY29_LATCH	H2ZSG0_LATCH	ENSLACP00000014550	ENSLACP00000000331	Uncharacterized protein.	Sema domain-containing protein.	0.899
H3AY29_LATCH	LOC102347877	ENSLACP00000014550	ENSLACP00000012157	Uncharacterized protein.	Uncharacterized protein.	0.486
H3AY29_LATCH	NRP1	ENSLACP00000014550	ENSLACP00000023533	Uncharacterized protein.	Neuropilin; Belongs to the neuropilin family.	0.717
H3AY29_LATCH	PLXNA3	ENSLACP00000014550	ENSLACP00000006959	Uncharacterized protein.	Sema domain-containing protein.	0.486
H3AY29_LATCH	PLXNA3-2	ENSLACP00000014550	ENSLACP00000002847	Uncharacterized protein.	Plexin A3.	0.486
H3AY29_LATCH	PLXND1	ENSLACP00000014550	ENSLACP00000013783	Uncharacterized protein.	Plexin D1.	0.498
H3AY29_LATCH	SEMA3A	ENSLACP00000014550	ENSLACP00000015743	Uncharacterized protein.	Semaphorin 3A; Belongs to the semaphorin family.	0.868