(44 nodes) Valine, leucine and isoleucine degradation, and Fatty acid beta-oxidation network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102356109	ETF domain-containing protein. (127 aa)
	HADHB	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (459 aa)
	CRYL1	Crystallin lambda 1. (319 aa)
	CPT2	Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (665 aa)
	OXSM	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (463 aa)
	H2ZYE8_LATCH	Acyl-CoA_dh_1 domain-containing protein. (100 aa)
	LOC102365715	Si:ch211-198n5.11. (627 aa)
	ACADL	Acyl-CoA dehydrogenase long chain. (448 aa)
	HADH	Hydroxyacyl-CoA dehydrogenase. (309 aa)
	HSD17B4	Hydroxysteroid 17-beta dehydrogenase 4. (740 aa)
	ECI2	Enoyl-CoA delta isomerase 2. (409 aa)
	HIBADH	3-hydroxyisobutyrate dehydrogenase. (251 aa)
	STOML1	Stomatin like 1. (336 aa)
	ECHS1	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	MCCC2	Methylcrotonoyl-CoA carboxylase 2. (285 aa)
	LOC102352162	Uncharacterized protein. (645 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (331 aa)
	LOC102351783	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family. (295 aa)
	LOC102355441	Cocaine- and amphetamine-regulated transcript 3. (119 aa)
	ACADM	Acyl-CoA dehydrogenase medium chain. (424 aa)
	ALDH9A1	Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family. (401 aa)
	LOC102362424	Cocaine- and amphetamine-regulated transcript 1. (112 aa)
	ETFA	Uncharacterized protein. (232 aa)
	HADHA	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (766 aa)
	PCCB	Propionyl-CoA carboxylase subunit beta. (555 aa)
	ALDH2	Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family. (524 aa)
	ACSS1	Acetyl-coenzyme A synthetase. (645 aa)
	EHHADH	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (537 aa)
	ACSS3	Acyl-CoA synthetase short chain family member 3. (714 aa)
	PCCA	Propionyl-CoA carboxylase subunit alpha. (711 aa)
	HLCS	Holocarboxylase synthetase. (738 aa)
	ECI1	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (194 aa)
	HIBCH	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (387 aa)
	ACOXL	Acyl-CoA oxidase like. (219 aa)
	MCAT	Malonyl-CoA-acyl carrier protein transacylase. (368 aa)
	ACOX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
	IVD	Isovaleryl-CoA dehydrogenase. (444 aa)
	ACADS	Acyl-CoA dehydrogenase short chain. (410 aa)
	MCCC1	Methylcrotonoyl-CoA carboxylase 1. (714 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (2312 aa)
	ALDH6A1	Aldehyde dehydrogenase 6 family member A1. (475 aa)
	ACSS2	Acyl-CoA synthetase short chain family member 2. (687 aa)
	MCEE	Methylmalonyl-CoA epimerase. (173 aa)
	ACOX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (708 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	ACOX1	ENSLACP00000020662	ENSLACP00000019825	Acetyl-CoA carboxylase alpha.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.467
ACACA	ACOX3	ENSLACP00000020662	ENSLACP00000022842	Acetyl-CoA carboxylase alpha.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.672
ACACA	ACOXL	ENSLACP00000020662	ENSLACP00000019275	Acetyl-CoA carboxylase alpha.	Acyl-CoA oxidase like.	0.460
ACACA	ECHS1	ENSLACP00000020662	ENSLACP00000005312	Acetyl-CoA carboxylase alpha.	Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.458
ACACA	ECI1	ENSLACP00000020662	ENSLACP00000016155	Acetyl-CoA carboxylase alpha.	Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.483
ACACA	ECI2	ENSLACP00000020662	ENSLACP00000004153	Acetyl-CoA carboxylase alpha.	Enoyl-CoA delta isomerase 2.	0.653
ACACA	EHHADH	ENSLACP00000020662	ENSLACP00000014258	Acetyl-CoA carboxylase alpha.	Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase.	0.483
ACACA	HADHA	ENSLACP00000020662	ENSLACP00000012505	Acetyl-CoA carboxylase alpha.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.	0.612
ACACA	HADHB	ENSLACP00000020662	ENSLACP00000000621	Acetyl-CoA carboxylase alpha.	Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family.	0.450
ACACA	HLCS	ENSLACP00000020662	ENSLACP00000015872	Acetyl-CoA carboxylase alpha.	Holocarboxylase synthetase.	0.870
ACACA	LOC102355441	ENSLACP00000020662	ENSLACP00000009134	Acetyl-CoA carboxylase alpha.	Cocaine- and amphetamine-regulated transcript 3.	0.474
ACACA	LOC102362424	ENSLACP00000020662	ENSLACP00000011617	Acetyl-CoA carboxylase alpha.	Cocaine- and amphetamine-regulated transcript 1.	0.473
ACACA	LOC102365715	ENSLACP00000020662	ENSLACP00000003160	Acetyl-CoA carboxylase alpha.	Si:ch211-198n5.11.	0.624
ACACA	MCAT	ENSLACP00000020662	ENSLACP00000019390	Acetyl-CoA carboxylase alpha.	Malonyl-CoA-acyl carrier protein transacylase.	0.696
ACACA	MCCC1	ENSLACP00000020662	ENSLACP00000020618	Acetyl-CoA carboxylase alpha.	Methylcrotonoyl-CoA carboxylase 1.	0.601
ACACA	MCCC2	ENSLACP00000020662	ENSLACP00000006528	Acetyl-CoA carboxylase alpha.	Methylcrotonoyl-CoA carboxylase 2.	0.624
ACACA	OXSM	ENSLACP00000020662	ENSLACP00000002085	Acetyl-CoA carboxylase alpha.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.771
ACACA	PCCA	ENSLACP00000020662	ENSLACP00000014574	Acetyl-CoA carboxylase alpha.	Propionyl-CoA carboxylase subunit alpha.	0.601
ACACA	PCCB	ENSLACP00000020662	ENSLACP00000013061	Acetyl-CoA carboxylase alpha.	Propionyl-CoA carboxylase subunit beta.	0.625
ACACA	STOML1	ENSLACP00000020662	ENSLACP00000005200	Acetyl-CoA carboxylase alpha.	Stomatin like 1.	0.430