(23 nodes) Mixed, incl. Bcl-2 family, and Cysteine-type endopeptidase activator activity involved in apoptotic process network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	H2ZRT7_LATCH	Uncharacterized protein. (483 aa)
	LOC102345199	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (115 aa)
	LOC102353910	Uncharacterized protein. (191 aa)
	LOC102363280	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
	BCL2L2	BCL2 like 2. (189 aa)
	LOC102359329	Uncharacterized protein. (981 aa)
	BAX	Uncharacterized protein. (223 aa)
	H3AD24_LATCH	CCHC-type domain-containing protein. (223 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3. (525 aa)
	LOC102349826	Cystatin domain-containing protein; Belongs to the cystatin family. (141 aa)
	BOK	BCL2 family apoptosis regulator BOK. (111 aa)
	BCL2L10	BCL2 like 10. (178 aa)
	BAD	Uncharacterized protein. (175 aa)
	BCL2L1	BCL2 like 1. (239 aa)
	CDKL1	Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily. (355 aa)
	MCL1	MCL1 apoptosis regulator, BCL2 family member. (207 aa)
	BSN	Bassoon presynaptic cytomatrix protein. (3467 aa)
	LOC102359041	Zgc:153993. (208 aa)
	APAF1	Apoptotic peptidase activating factor 1. (1202 aa)
	TMEM198	Transmembrane protein 198. (365 aa)
	LOC102357497	DUF4203 domain-containing protein. (354 aa)
	BAK1	BCL2 antagonist/killer 1. (239 aa)
	M3XHJ5_LATCH	Uncharacterized protein. (158 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BAK1	ENSLACP00000014568	ENSLACP00000018296	Apoptotic peptidase activating factor 1.	BCL2 antagonist/killer 1.	0.670
APAF1	BAX	ENSLACP00000014568	ENSLACP00000007049	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.800
APAF1	BCL2L1	ENSLACP00000014568	ENSLACP00000011299	Apoptotic peptidase activating factor 1.	BCL2 like 1.	0.840
APAF1	BCL2L10	ENSLACP00000014568	ENSLACP00000010648	Apoptotic peptidase activating factor 1.	BCL2 like 10.	0.670
APAF1	BCL2L2	ENSLACP00000014568	ENSLACP00000006748	Apoptotic peptidase activating factor 1.	BCL2 like 2.	0.717
APAF1	BOK	ENSLACP00000014568	ENSLACP00000009914	Apoptotic peptidase activating factor 1.	BCL2 family apoptosis regulator BOK.	0.670
APAF1	H2ZRT7_LATCH	ENSLACP00000014568	ENSLACP00000000108	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.712
APAF1	H3AD24_LATCH	ENSLACP00000014568	ENSLACP00000007545	Apoptotic peptidase activating factor 1.	CCHC-type domain-containing protein.	0.790
APAF1	LOC102345199	ENSLACP00000014568	ENSLACP00000001282	Apoptotic peptidase activating factor 1.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
APAF1	LOC102353910	ENSLACP00000014568	ENSLACP00000004414	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.670
APAF1	LOC102357497	ENSLACP00000014568	ENSLACP00000017947	Apoptotic peptidase activating factor 1.	DUF4203 domain-containing protein.	0.790
APAF1	LOC102359041	ENSLACP00000014568	ENSLACP00000012675	Apoptotic peptidase activating factor 1.	Zgc:153993.	0.670
APAF1	LOC102359329	ENSLACP00000014568	ENSLACP00000006976	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.790
APAF1	LOC102363280	ENSLACP00000014568	ENSLACP00000005807	Apoptotic peptidase activating factor 1.	Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.	0.999
APAF1	M3XHJ5_LATCH	ENSLACP00000014568	ENSLACP00000022201	Apoptotic peptidase activating factor 1.	Uncharacterized protein.	0.568
APAF1	MCL1	ENSLACP00000014568	ENSLACP00000012090	Apoptotic peptidase activating factor 1.	MCL1 apoptosis regulator, BCL2 family member.	0.773
APAF1	TMEM198	ENSLACP00000014568	ENSLACP00000017893	Apoptotic peptidase activating factor 1.	Transmembrane protein 198.	0.790
ARHGEF3	BOK	ENSLACP00000007681	ENSLACP00000009914	Rho guanine nucleotide exchange factor 3.	BCL2 family apoptosis regulator BOK.	0.700
ARHGEF3	CDKL1	ENSLACP00000007681	ENSLACP00000011700	Rho guanine nucleotide exchange factor 3.	Cyclin dependent kinase like 1; Belongs to the protein kinase superfamily.	0.860
BAD	BAK1	ENSLACP00000011265	ENSLACP00000018296	Uncharacterized protein.	BCL2 antagonist/killer 1.	0.786