(5 nodes) Inflammasome complex network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102348725	Uncharacterized protein. (641 aa)
	LOC102349920	Uncharacterized protein. (199 aa)
	NLRC4	NLR family CARD domain containing 4. (1032 aa)
	LOC102363742	Uncharacterized protein; Belongs to the peptidase C14A family. (394 aa)
	AIM2	HIN-200 domain-containing protein. (205 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIM2	LOC102349920	ENSLACP00000021844	ENSLACP00000010067	HIN-200 domain-containing protein.	Uncharacterized protein.	0.948
AIM2	LOC102363742	ENSLACP00000021844	ENSLACP00000016224	HIN-200 domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.861
AIM2	NLRC4	ENSLACP00000021844	ENSLACP00000014259	HIN-200 domain-containing protein.	NLR family CARD domain containing 4.	0.910
LOC102348725	LOC102349920	ENSLACP00000003437	ENSLACP00000010067	Uncharacterized protein.	Uncharacterized protein.	0.966
LOC102348725	LOC102363742	ENSLACP00000003437	ENSLACP00000016224	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.931
LOC102349920	AIM2	ENSLACP00000010067	ENSLACP00000021844	Uncharacterized protein.	HIN-200 domain-containing protein.	0.948
LOC102349920	LOC102348725	ENSLACP00000010067	ENSLACP00000003437	Uncharacterized protein.	Uncharacterized protein.	0.966
LOC102349920	LOC102363742	ENSLACP00000010067	ENSLACP00000016224	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.996
LOC102349920	NLRC4	ENSLACP00000010067	ENSLACP00000014259	Uncharacterized protein.	NLR family CARD domain containing 4.	0.745
LOC102363742	AIM2	ENSLACP00000016224	ENSLACP00000021844	Uncharacterized protein; Belongs to the peptidase C14A family.	HIN-200 domain-containing protein.	0.861
LOC102363742	LOC102348725	ENSLACP00000016224	ENSLACP00000003437	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.931
LOC102363742	LOC102349920	ENSLACP00000016224	ENSLACP00000010067	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.996
LOC102363742	NLRC4	ENSLACP00000016224	ENSLACP00000014259	Uncharacterized protein; Belongs to the peptidase C14A family.	NLR family CARD domain containing 4.	0.912
NLRC4	AIM2	ENSLACP00000014259	ENSLACP00000021844	NLR family CARD domain containing 4.	HIN-200 domain-containing protein.	0.910
NLRC4	LOC102349920	ENSLACP00000014259	ENSLACP00000010067	NLR family CARD domain containing 4.	Uncharacterized protein.	0.745
NLRC4	LOC102363742	ENSLACP00000014259	ENSLACP00000016224	NLR family CARD domain containing 4.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.912