(77 nodes) Myosin II complex, and Striated Muscle Contraction network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZU79_LATCH	Uncharacterized protein. (236 aa)
	H2ZUL3_LATCH	Uncharacterized protein. (225 aa)
	H2ZVS2_LATCH	Uncharacterized protein. (258 aa)
	H2ZX48_LATCH	Uncharacterized protein. (241 aa)
	MYLPF	Myosin light chain, phosphorylatable, fast skeletal muscle. (205 aa)
	SMPX	Small muscle protein X-linked. (85 aa)
	TNNI3	Uncharacterized protein. (240 aa)
	LOC102352251	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (460 aa)
	NRAP	Nebulin related anchoring protein. (1783 aa)
	TPM3	Tropomyosin 3; Belongs to the tropomyosin family. (286 aa)
	LOC102348511	Uncharacterized protein. (1306 aa)
	TNNT1	Troponin T1, slow skeletal type. (253 aa)
	LOC102364634	Uncharacterized protein. (377 aa)
	H3A495_LATCH	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1894 aa)
	ACTG2	Actin gamma 2, smooth muscle. (353 aa)
	MYL1	Myosin light chain 1. (211 aa)
	H3A5B1_LATCH	Uncharacterized protein. (240 aa)
	MYL5	Myosin light chain 5. (188 aa)
	TMOD3	Tropomodulin 3. (352 aa)
	ACTA2	Uncharacterized protein. (338 aa)
	MYH2	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
	MYH10	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2012 aa)
	LOC102363221	Myosin_tail_1 domain-containing protein. (848 aa)
	MYOZ1	Myozenin 1. (313 aa)
	LOC102347576	SH3 domain-containing protein. (2968 aa)
	H3AF74_LATCH	Uncharacterized protein. (204 aa)
	TNNI2	Troponin I2, fast skeletal type. (190 aa)
	H3AI48_LATCH	Uncharacterized protein. (205 aa)
	H3AKF2_LATCH	Uncharacterized protein. (219 aa)
	H3AKU7_LATCH	Uncharacterized protein. (206 aa)
	MYL3	Myosin, light chain 13. (195 aa)
	MYH9	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
	H3ALZ3_LATCH	Uncharacterized protein. (222 aa)
	GATD1	Glutamine amidotransferase like class 1 domain containing 1. (215 aa)
	H3AP16_LATCH	Uncharacterized protein. (239 aa)
	LOC102353564	Uncharacterized protein. (161 aa)
	MYOZ2	Myozenin 2. (273 aa)
	MYO1H	Myosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1040 aa)
	DNAAF3	Uncharacterized protein. (484 aa)
	H3AQT8_LATCH	Uncharacterized protein. (223 aa)
	LOC102346545	Myosin, light chain 12, genome duplicate 2. (172 aa)
	TNNT3	Troponin T3, fast skeletal type. (227 aa)
	TNNI1	Troponin I1, slow skeletal type. (171 aa)
	PDLIM3	PDZ and LIM domain 3. (356 aa)
	TNNT2	Troponin T2, cardiac type. (286 aa)
	TPM2	Tropomyosin 2; Belongs to the tropomyosin family. (284 aa)
	LMOD1	Leiomodin 1. (603 aa)
	ACTC1	Zgc:86709. (377 aa)
	CALD1	Caldesmon 1. (796 aa)
	H3AVX9_LATCH	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1705 aa)
	MYH7	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
	LOC102361251	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2203 aa)
	H3AXH2_LATCH	Uncharacterized protein. (210 aa)
	H3AXK4_LATCH	Myocardial zonula adherens protein. (494 aa)
	MYH6	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1936 aa)
	CPT1C	Carnitine palmitoyltransferase 1C; Belongs to the carnitine/choline acetyltransferase family. (770 aa)
	TPM1	Alpha-tropomyosin; Belongs to the tropomyosin family. (328 aa)
	H3AYN1_LATCH	Uncharacterized protein. (1008 aa)
	MYL7	Myosin light chain 7. (182 aa)
	TMOD1	Tropomodulin 1. (361 aa)
	LOC102350553	Uncharacterized protein. (232 aa)
	MYL2	Myosin light chain 2. (148 aa)
	MYO7B	Myosin VIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2098 aa)
	MYL9	Myosin light chain 9. (173 aa)
	CSRP3	Cysteine and glycine rich protein 3. (192 aa)
	ACTN2	Actinin alpha 2. (879 aa)
	H3BDP0_LATCH	Uncharacterized protein. (48 aa)
	ACTN3	Actinin alpha 3a. (907 aa)
	LOC102361066	EF-hand domain-containing protein. (100 aa)
	H3BF30_LATCH	Uncharacterized protein. (199 aa)
	H3BGT2_LATCH	Uncharacterized protein. (277 aa)
	TNNC1	Troponin C type 1a (slow). (164 aa)
	ACTN4	Uncharacterized protein. (888 aa)
	H3BH85_LATCH	Uncharacterized protein. (164 aa)
	LOC102352170	Uncharacterized protein. (163 aa)
	RTN1	Reticulon. (680 aa)
	MYBPC3	Myosin binding protein C, cardiac. (1267 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA2	ACTG2	ENSLACP00000005571	ENSLACP00000004482	Uncharacterized protein.	Actin gamma 2, smooth muscle.	0.900
ACTA2	ACTN2	ENSLACP00000005571	ENSLACP00000018992	Uncharacterized protein.	Actinin alpha 2.	0.568
ACTA2	ACTN3	ENSLACP00000005571	ENSLACP00000020125	Uncharacterized protein.	Actinin alpha 3a.	0.567
ACTA2	ACTN4	ENSLACP00000005571	ENSLACP00000021197	Uncharacterized protein.	Uncharacterized protein.	0.440
ACTA2	H3A495_LATCH	ENSLACP00000005571	ENSLACP00000004466	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.443
ACTA2	H3AVX9_LATCH	ENSLACP00000005571	ENSLACP00000013800	Uncharacterized protein.	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.413
ACTA2	H3AXK4_LATCH	ENSLACP00000005571	ENSLACP00000014375	Uncharacterized protein.	Myocardial zonula adherens protein.	0.447
ACTA2	H3BDP0_LATCH	ENSLACP00000005571	ENSLACP00000020011	Uncharacterized protein.	Uncharacterized protein.	0.443
ACTA2	LMOD1	ENSLACP00000005571	ENSLACP00000013084	Uncharacterized protein.	Leiomodin 1.	0.463
ACTA2	LOC102346545	ENSLACP00000005571	ENSLACP00000012103	Uncharacterized protein.	Myosin, light chain 12, genome duplicate 2.	0.456
ACTA2	LOC102361066	ENSLACP00000005571	ENSLACP00000020192	Uncharacterized protein.	EF-hand domain-containing protein.	0.574
ACTA2	LOC102361251	ENSLACP00000005571	ENSLACP00000014137	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.403
ACTA2	LOC102363221	ENSLACP00000005571	ENSLACP00000007054	Uncharacterized protein.	Myosin_tail_1 domain-containing protein.	0.403
ACTA2	MYH10	ENSLACP00000005571	ENSLACP00000006395	Uncharacterized protein.	Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.413
ACTA2	MYH2	ENSLACP00000005571	ENSLACP00000005685	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.443
ACTA2	MYH6	ENSLACP00000005571	ENSLACP00000014532	Uncharacterized protein.	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.443
ACTA2	MYH7	ENSLACP00000005571	ENSLACP00000013844	Uncharacterized protein.	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.443
ACTA2	MYH9	ENSLACP00000005571	ENSLACP00000010518	Uncharacterized protein.	Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.938
ACTA2	MYL1	ENSLACP00000005571	ENSLACP00000004713	Uncharacterized protein.	Myosin light chain 1.	0.574
ACTA2	MYL2	ENSLACP00000005571	ENSLACP00000017426	Uncharacterized protein.	Myosin light chain 2.	0.453