(24 nodes) Mixed, incl. Egg coat, and Cerebral cavernous malformations 2 network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRIT1	KRIT1 ankyrin repeat containing. (733 aa)
	H2ZUV5_LATCH	IgGFc_binding domain-containing protein. (401 aa)
	H2ZW79_LATCH	Uncharacterized protein. (2340 aa)
	CCM2	CCM2 scaffold protein. (447 aa)
	LOC102346338	ZP domain-containing protein. (328 aa)
	CCM2L	CCM2 like scaffold protein. (594 aa)
	H3A0X0_LATCH	IgGFc_binding domain-containing protein. (408 aa)
	H3A575_LATCH	Uncharacterized protein. (388 aa)
	LOC102356445	Uncharacterized protein. (385 aa)
	H3A8E7_LATCH	ZP domain-containing protein. (668 aa)
	LOC102359505	ZP domain-containing protein. (965 aa)
	H3AEM0_LATCH	Uncharacterized protein. (373 aa)
	FAM107B	Family with sequence similarity 107 member B. (162 aa)
	H3AHA9_LATCH	Uncharacterized protein. (348 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	H3AJ09_LATCH	Uncharacterized protein. (249 aa)
	LOC102356596	Uncharacterized protein. (409 aa)
	MAP3K3	Mitogen-activated protein kinase kinase kinase 3. (658 aa)
	FCGBP	Uncharacterized protein. (2249 aa)
	LOC102359022	Chitin-binding type-2 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (461 aa)
	LOC102346997	ZP domain-containing protein. (825 aa)
	LOC102350357	Uncharacterized protein. (577 aa)
	LOC102351904	Zgc:65851; Belongs to the intermediate filament family. (476 aa)
	LOC106706718	Uncharacterized protein. (182 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCM2	ITGB1BP1	ENSLACP00000001878	ENSLACP00000009080	CCM2 scaffold protein.	Integrin subunit beta 1 binding protein 1.	0.817
CCM2	KRIT1	ENSLACP00000001878	ENSLACP00000000694	CCM2 scaffold protein.	KRIT1 ankyrin repeat containing.	0.972
CCM2	LOC102346338	ENSLACP00000001878	ENSLACP00000002084	CCM2 scaffold protein.	ZP domain-containing protein.	0.422
CCM2	LOC102350357	ENSLACP00000001878	ENSLACP00000018303	CCM2 scaffold protein.	Uncharacterized protein.	0.917
CCM2	MAP3K3	ENSLACP00000001878	ENSLACP00000014058	CCM2 scaffold protein.	Mitogen-activated protein kinase kinase kinase 3.	0.917
CCM2L	ITGB1BP1	ENSLACP00000003287	ENSLACP00000009080	CCM2 like scaffold protein.	Integrin subunit beta 1 binding protein 1.	0.685
CCM2L	KRIT1	ENSLACP00000003287	ENSLACP00000000694	CCM2 like scaffold protein.	KRIT1 ankyrin repeat containing.	0.862
CCM2L	LOC102346338	ENSLACP00000003287	ENSLACP00000002084	CCM2 like scaffold protein.	ZP domain-containing protein.	0.422
CCM2L	LOC102350357	ENSLACP00000003287	ENSLACP00000018303	CCM2 like scaffold protein.	Uncharacterized protein.	0.666
CCM2L	MAP3K3	ENSLACP00000003287	ENSLACP00000014058	CCM2 like scaffold protein.	Mitogen-activated protein kinase kinase kinase 3.	0.666
FAM107B	LOC102346338	ENSLACP00000008604	ENSLACP00000002084	Family with sequence similarity 107 member B.	ZP domain-containing protein.	0.535
FCGBP	H2ZUV5_LATCH	ENSLACP00000015110	ENSLACP00000001176	Uncharacterized protein.	IgGFc_binding domain-containing protein.	0.669
FCGBP	H3A0X0_LATCH	ENSLACP00000015110	ENSLACP00000003291	Uncharacterized protein.	IgGFc_binding domain-containing protein.	0.771
H2ZUV5_LATCH	FCGBP	ENSLACP00000001176	ENSLACP00000015110	IgGFc_binding domain-containing protein.	Uncharacterized protein.	0.669
H2ZUV5_LATCH	H2ZW79_LATCH	ENSLACP00000001176	ENSLACP00000001650	IgGFc_binding domain-containing protein.	Uncharacterized protein.	0.450
H2ZW79_LATCH	H2ZUV5_LATCH	ENSLACP00000001650	ENSLACP00000001176	Uncharacterized protein.	IgGFc_binding domain-containing protein.	0.450
H2ZW79_LATCH	H3A0X0_LATCH	ENSLACP00000001650	ENSLACP00000003291	Uncharacterized protein.	IgGFc_binding domain-containing protein.	0.558
H3A0X0_LATCH	FCGBP	ENSLACP00000003291	ENSLACP00000015110	IgGFc_binding domain-containing protein.	Uncharacterized protein.	0.771
H3A0X0_LATCH	H2ZW79_LATCH	ENSLACP00000003291	ENSLACP00000001650	IgGFc_binding domain-containing protein.	Uncharacterized protein.	0.558
H3A575_LATCH	LOC102346338	ENSLACP00000004796	ENSLACP00000002084	Uncharacterized protein.	ZP domain-containing protein.	0.543