(54 nodes) Mixed, incl. Catenin binding domain superfamily, and Formation of the cornified envelope network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H2ZTV2_LATCH	Uncharacterized protein. (383 aa)
	CDH8	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (713 aa)
	CDH18	Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (791 aa)
	H2ZY56_LATCH	Uncharacterized protein. (127 aa)
	LOC102361492	Uncharacterized protein. (1086 aa)
	H3A003_LATCH	Uncharacterized protein. (1739 aa)
	H3A0S9_LATCH	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (898 aa)
	CDH12	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins. (727 aa)
	PCDH9	Protocadherin 9. (1032 aa)
	H3A4U8_LATCH	Uncharacterized protein. (2171 aa)
	CTNNA3	Uncharacterized protein. (213 aa)
	CDH4	Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (724 aa)
	KAZN-2	Uncharacterized protein. (125 aa)
	LOC102361769	Uncharacterized protein. (924 aa)
	H3A7F2_LATCH	Uncharacterized protein. (620 aa)
	CDH11	Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
	DSP	Desmoplakin. (2623 aa)
	CDH1	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
	JUP	Junction plakoglobin. (694 aa)
	ISLR	Immunoglobulin superfamily containing leucine rich repeat. (673 aa)
	PCDH7	Protocadherin 7b. (1051 aa)
	LOC102346231	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (714 aa)
	TMEM215	Transmembrane protein 215. (225 aa)
	CDH15	Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (797 aa)
	LOC102354257	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
	BRINP3	BMP/retinoic acid inducible neural specific 3. (766 aa)
	KAZN	Uncharacterized protein. (640 aa)
	PCDH20	Uncharacterized protein. (875 aa)
	H3ARS9_LATCH	Uncharacterized protein. (86 aa)
	CDH5	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (772 aa)
	CDH16	Cadherin 16, KSP-cadherin. (839 aa)
	H3AU51_LATCH	Uncharacterized protein. (706 aa)
	PKP1	Plakophilin 1. (744 aa)
	CTNND2	Uncharacterized protein. (368 aa)
	H3AXL4_LATCH	Uncharacterized protein. (953 aa)
	H3AZ26_LATCH	Uncharacterized protein. (79 aa)
	CTNNAL1	Catenin alpha like 1. (674 aa)
	LOC102361707	P53 apoptosis effector related to pmp22. (183 aa)
	LOC102361982	Uncharacterized protein. (182 aa)
	H3B296_LATCH	Uncharacterized protein. (380 aa)
	CDH7	Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
	CDH24	Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
	H3B4B5_LATCH	Uncharacterized protein. (534 aa)
	LGALSL	Galectin. (170 aa)
	PCDH11Y	Protocadherin 11. (1013 aa)
	ARVCF	ARVCF delta catenin family member. (870 aa)
	EVPL	Envoplakin a. (2004 aa)
	LOC102358216	Uncharacterized protein. (809 aa)
	LOC102357400	Uncharacterized protein. (814 aa)
	M3XIR5_LATCH	Uncharacterized protein. (217 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (894 aa)
	M3XJ81_LATCH	Uncharacterized protein. (117 aa)
	PKP2	Uncharacterized protein. (815 aa)
	PKP4	Plakophilin 4. (1190 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARVCF	CDH1	ENSLACP00000019051	ENSLACP00000006055	ARVCF delta catenin family member.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.832
ARVCF	CDH11	ENSLACP00000019051	ENSLACP00000005664	ARVCF delta catenin family member.	Cadherin 11; Cadherins are calcium-dependent cell adhesion proteins.	0.662
ARVCF	CDH12	ENSLACP00000019051	ENSLACP00000003276	ARVCF delta catenin family member.	Cadherin 12; Cadherins are calcium-dependent cell adhesion proteins.	0.619
ARVCF	CDH15	ENSLACP00000019051	ENSLACP00000008616	ARVCF delta catenin family member.	Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins.	0.681
ARVCF	CDH16	ENSLACP00000019051	ENSLACP00000013008	ARVCF delta catenin family member.	Cadherin 16, KSP-cadherin.	0.678
ARVCF	CDH18	ENSLACP00000019051	ENSLACP00000001329	ARVCF delta catenin family member.	Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins.	0.646
ARVCF	CDH2	ENSLACP00000019051	ENSLACP00000022733	ARVCF delta catenin family member.	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	0.681
ARVCF	CDH24	ENSLACP00000019051	ENSLACP00000016661	ARVCF delta catenin family member.	Cadherin 24; Cadherins are calcium-dependent cell adhesion proteins.	0.538
ARVCF	CDH4	ENSLACP00000019051	ENSLACP00000004699	ARVCF delta catenin family member.	Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins.	0.681
ARVCF	CDH5	ENSLACP00000019051	ENSLACP00000012760	ARVCF delta catenin family member.	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	0.831
ARVCF	CDH7	ENSLACP00000019051	ENSLACP00000016501	ARVCF delta catenin family member.	Cadherin 7; Cadherins are calcium-dependent cell adhesion proteins.	0.644
ARVCF	CDH8	ENSLACP00000019051	ENSLACP00000001253	ARVCF delta catenin family member.	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.	0.644
ARVCF	CTNNA3	ENSLACP00000019051	ENSLACP00000004684	ARVCF delta catenin family member.	Uncharacterized protein.	0.699
ARVCF	CTNND2	ENSLACP00000019051	ENSLACP00000013244	ARVCF delta catenin family member.	Uncharacterized protein.	0.877
ARVCF	H3A003_LATCH	ENSLACP00000019051	ENSLACP00000002974	ARVCF delta catenin family member.	Uncharacterized protein.	0.411
ARVCF	H3A0S9_LATCH	ENSLACP00000019051	ENSLACP00000003250	ARVCF delta catenin family member.	Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.539
ARVCF	H3A4U8_LATCH	ENSLACP00000019051	ENSLACP00000004669	ARVCF delta catenin family member.	Uncharacterized protein.	0.411
ARVCF	H3ARS9_LATCH	ENSLACP00000019051	ENSLACP00000012350	ARVCF delta catenin family member.	Uncharacterized protein.	0.699
ARVCF	H3AU51_LATCH	ENSLACP00000019051	ENSLACP00000013172	ARVCF delta catenin family member.	Uncharacterized protein.	0.699
ARVCF	H3B296_LATCH	ENSLACP00000019051	ENSLACP00000016017	ARVCF delta catenin family member.	Uncharacterized protein.	0.699