(13 nodes) Caspase activation via Dependence Receptors in the absence of ligand, and Motor neuron axon guidance network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (484 aa)
	LOC102356949	Netrin 2. (513 aa)
	UNC5C	Unc-5 netrin receptor C. (754 aa)
	H3ACM3_LATCH	Ig-like domain-containing protein. (135 aa)
	NTN1	Netrin 1. (604 aa)
	H3AGE3_LATCH	Uncharacterized protein. (137 aa)
	LOC102346244	Uncharacterized protein. (567 aa)
	H3AQC0_LATCH	Uncharacterized protein. (690 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa)
	H3B3H4_LATCH	Uncharacterized protein. (575 aa)
	IGDCC4	Immunoglobulin superfamily DCC subclass member 4. (1039 aa)
	IGDCC3	Immunoglobulin superfamily DCC subclass member 3. (654 aa)
	DRAXIN	Dorsal inhibitory axon guidance protein. (347 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	ENSLACP00000012610	ENSLACP00000000307	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.997
APPL1	H3ACM3_LATCH	ENSLACP00000012610	ENSLACP00000007394	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Ig-like domain-containing protein.	0.967
APPL1	H3AGE3_LATCH	ENSLACP00000012610	ENSLACP00000008714	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Uncharacterized protein.	0.967
APPL1	H3AQC0_LATCH	ENSLACP00000012610	ENSLACP00000011841	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Uncharacterized protein.	0.967
APPL1	H3B3H4_LATCH	ENSLACP00000012610	ENSLACP00000016445	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Uncharacterized protein.	0.967
APPL1	IGDCC3	ENSLACP00000012610	ENSLACP00000017953	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Immunoglobulin superfamily DCC subclass member 3.	0.967
APPL1	IGDCC4	ENSLACP00000012610	ENSLACP00000016888	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Immunoglobulin superfamily DCC subclass member 4.	0.967
APPL2	APPL1	ENSLACP00000000307	ENSLACP00000012610	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.997
APPL2	H3ACM3_LATCH	ENSLACP00000000307	ENSLACP00000007394	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Ig-like domain-containing protein.	0.967
APPL2	H3AGE3_LATCH	ENSLACP00000000307	ENSLACP00000008714	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.967
APPL2	H3AQC0_LATCH	ENSLACP00000000307	ENSLACP00000011841	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.967
APPL2	H3B3H4_LATCH	ENSLACP00000000307	ENSLACP00000016445	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Uncharacterized protein.	0.967
APPL2	IGDCC3	ENSLACP00000000307	ENSLACP00000017953	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Immunoglobulin superfamily DCC subclass member 3.	0.967
APPL2	IGDCC4	ENSLACP00000000307	ENSLACP00000016888	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Immunoglobulin superfamily DCC subclass member 4.	0.967
DRAXIN	H3ACM3_LATCH	ENSLACP00000021794	ENSLACP00000007394	Dorsal inhibitory axon guidance protein.	Ig-like domain-containing protein.	0.673
DRAXIN	H3AGE3_LATCH	ENSLACP00000021794	ENSLACP00000008714	Dorsal inhibitory axon guidance protein.	Uncharacterized protein.	0.777
DRAXIN	H3AQC0_LATCH	ENSLACP00000021794	ENSLACP00000011841	Dorsal inhibitory axon guidance protein.	Uncharacterized protein.	0.777
DRAXIN	H3B3H4_LATCH	ENSLACP00000021794	ENSLACP00000016445	Dorsal inhibitory axon guidance protein.	Uncharacterized protein.	0.541
DRAXIN	IGDCC3	ENSLACP00000021794	ENSLACP00000017953	Dorsal inhibitory axon guidance protein.	Immunoglobulin superfamily DCC subclass member 3.	0.541
DRAXIN	IGDCC4	ENSLACP00000021794	ENSLACP00000016888	Dorsal inhibitory axon guidance protein.	Immunoglobulin superfamily DCC subclass member 4.	0.626