(13 nodes) Signaling by ROBO receptors network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102357836	Ig-like domain-containing protein. (135 aa)
	ROBO1	Roundabout guidance receptor 1. (1421 aa)
	SLIT1	Slit guidance ligand 1. (925 aa)
	ROBO2	Roundabout guidance receptor 2. (1213 aa)
	H3AC70_LATCH	LRRNT domain-containing protein. (132 aa)
	H3AM86_LATCH	Uncharacterized protein. (104 aa)
	SLIT2	Slit guidance ligand 2. (1372 aa)
	ROBO3	Roundabout, axon guidance receptor, homolog 3 (Drosophila). (1469 aa)
	H3AZJ1_LATCH	Uncharacterized protein. (779 aa)
	ROBO4	Uncharacterized protein. (277 aa)
	H3BCU0_LATCH	LRRNT domain-containing protein. (102 aa)
	LOC106705389	Roundabout, axon guidance receptor, homolog 2 (Drosophila). (129 aa)
	SLIT3	Slit guidance ligand 3. (635 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3AC70_LATCH	H3AM86_LATCH	ENSLACP00000007241	ENSLACP00000010757	LRRNT domain-containing protein.	Uncharacterized protein.	0.483
H3AC70_LATCH	H3AZJ1_LATCH	ENSLACP00000007241	ENSLACP00000015062	LRRNT domain-containing protein.	Uncharacterized protein.	0.699
H3AC70_LATCH	LOC102357836	ENSLACP00000007241	ENSLACP00000001590	LRRNT domain-containing protein.	Ig-like domain-containing protein.	0.699
H3AC70_LATCH	LOC106705389	ENSLACP00000007241	ENSLACP00000022689	LRRNT domain-containing protein.	Roundabout, axon guidance receptor, homolog 2 (Drosophila).	0.699
H3AC70_LATCH	ROBO1	ENSLACP00000007241	ENSLACP00000003115	LRRNT domain-containing protein.	Roundabout guidance receptor 1.	0.699
H3AC70_LATCH	ROBO2	ENSLACP00000007241	ENSLACP00000006310	LRRNT domain-containing protein.	Roundabout guidance receptor 2.	0.699
H3AC70_LATCH	ROBO3	ENSLACP00000007241	ENSLACP00000012994	LRRNT domain-containing protein.	Roundabout, axon guidance receptor, homolog 3 (Drosophila).	0.699
H3AC70_LATCH	ROBO4	ENSLACP00000007241	ENSLACP00000015378	LRRNT domain-containing protein.	Uncharacterized protein.	0.483
H3AC70_LATCH	SLIT1	ENSLACP00000007241	ENSLACP00000006092	LRRNT domain-containing protein.	Slit guidance ligand 1.	0.908
H3AC70_LATCH	SLIT2	ENSLACP00000007241	ENSLACP00000012299	LRRNT domain-containing protein.	Slit guidance ligand 2.	0.900
H3AC70_LATCH	SLIT3	ENSLACP00000007241	ENSLACP00000023414	LRRNT domain-containing protein.	Slit guidance ligand 3.	0.910
H3AM86_LATCH	H3AC70_LATCH	ENSLACP00000010757	ENSLACP00000007241	Uncharacterized protein.	LRRNT domain-containing protein.	0.483
H3AM86_LATCH	H3BCU0_LATCH	ENSLACP00000010757	ENSLACP00000019711	Uncharacterized protein.	LRRNT domain-containing protein.	0.483
H3AM86_LATCH	LOC102357836	ENSLACP00000010757	ENSLACP00000001590	Uncharacterized protein.	Ig-like domain-containing protein.	0.845
H3AM86_LATCH	LOC106705389	ENSLACP00000010757	ENSLACP00000022689	Uncharacterized protein.	Roundabout, axon guidance receptor, homolog 2 (Drosophila).	0.863
H3AM86_LATCH	ROBO2	ENSLACP00000010757	ENSLACP00000006310	Uncharacterized protein.	Roundabout guidance receptor 2.	0.899
H3AM86_LATCH	SLIT1	ENSLACP00000010757	ENSLACP00000006092	Uncharacterized protein.	Slit guidance ligand 1.	0.483
H3AM86_LATCH	SLIT2	ENSLACP00000010757	ENSLACP00000012299	Uncharacterized protein.	Slit guidance ligand 2.	0.483
H3AM86_LATCH	SLIT3	ENSLACP00000010757	ENSLACP00000023414	Uncharacterized protein.	Slit guidance ligand 3.	0.483
H3AZJ1_LATCH	H3AC70_LATCH	ENSLACP00000015062	ENSLACP00000007241	Uncharacterized protein.	LRRNT domain-containing protein.	0.699