10 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102354291	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (169 aa)
	NOS1	Nitric oxide synthase 1. (1476 aa)
	CAVIN1	Caveolae associated protein 1. (358 aa)
	CAV2	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (163 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	DHRS13	Dehydrogenase/reductase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
	FLOT2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (471 aa)
	NOSIP	Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family. (308 aa)
	NOS2	Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	CAV2	ENSLACP00000014173	ENSLACP00000014086	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.933
CAV1	CAVIN1	ENSLACP00000014173	ENSLACP00000012159	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1.	0.858
CAV1	FLOT2	ENSLACP00000014173	ENSLACP00000014570	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.502
CAV1	LOC102354291	ENSLACP00000014173	ENSLACP00000002046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.564
CAV1	NOS1	ENSLACP00000014173	ENSLACP00000007966	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 1.	0.616
CAV1	NOS2	ENSLACP00000014173	ENSLACP00000020145	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.616
CAV2	CAV1	ENSLACP00000014086	ENSLACP00000014173	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.933
CAV2	CAV3	ENSLACP00000014086	ENSLACP00000020888	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.976
CAV2	CAVIN1	ENSLACP00000014086	ENSLACP00000012159	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1.	0.788
CAV2	FLOT2	ENSLACP00000014086	ENSLACP00000014570	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.522
CAV2	LOC102354291	ENSLACP00000014086	ENSLACP00000002046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.982
CAV2	NOS1	ENSLACP00000014086	ENSLACP00000007966	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 1.	0.404
CAV2	NOS2	ENSLACP00000014086	ENSLACP00000020145	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.404
CAV3	CAV2	ENSLACP00000020888	ENSLACP00000014086	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.976
CAV3	CAVIN1	ENSLACP00000020888	ENSLACP00000012159	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolae associated protein 1.	0.903
CAV3	FLOT2	ENSLACP00000020888	ENSLACP00000014570	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily.	0.551
CAV3	LOC102354291	ENSLACP00000020888	ENSLACP00000002046	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.572
CAV3	NOS1	ENSLACP00000020888	ENSLACP00000007966	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase 1.	0.714
CAV3	NOS2	ENSLACP00000020888	ENSLACP00000020145	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Nitric oxide synthase; Produces nitric oxide (NO).	0.714
CAVIN1	CAV1	ENSLACP00000012159	ENSLACP00000014173	Caveolae associated protein 1.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.858