(89 nodes) Mixed, incl. Myc-type, basic helix-loop-helix (bHLH) domain, and Zinc-binding domain present in Lin-11, Isl-1, Mec-3. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZFPM2	Zinc finger protein, FOG family member 2. (979 aa)
	MEF2A	Myocyte enhancer factor 2A. (468 aa)
	LOC102354258	Si:ch211-246m6.4. (181 aa)
	SSBP3	Single stranded DNA binding protein 3. (301 aa)
	FOXF2	Forkhead box F2a. (379 aa)
	LOC102367663	Achaete-scute family bHLH transcription factor 1b. (177 aa)
	LMO2	LIM domain only 2. (158 aa)
	H2ZYE4_LATCH	Fli-1 proto-oncogene, ETS transcription factor b. (470 aa)
	TBX5	T-box transcription factor 5. (522 aa)
	GATA6	GATA binding protein 6. (503 aa)
	MYB	MYB proto-oncogene, transcription factor. (761 aa)
	ERG	ETS transcription factor ERG. (484 aa)
	SSBP2	Single stranded DNA binding protein 2. (376 aa)
	TCF4	Transcription factor 4. (701 aa)
	NKX3-2	NK3 homeobox 2. (282 aa)
	ETV2	ETS domain-containing protein. (110 aa)
	TCF24	Transcription factor 24. (187 aa)
	ESM1	Endothelial cell specific molecule 1. (185 aa)
	HAND2	Heart and neural crest derivatives expressed 2. (210 aa)
	H3A5U9_LATCH	LIM domain only 3. (81 aa)
	H3A6F4_LATCH	Homeobox domain-containing protein. (171 aa)
	PHOX2B	Paired like homeobox 2B. (287 aa)
	TCF21	Transcription factor 21. (179 aa)
	SOX1	SRY-box transcription factor 1. (342 aa)
	LOC102353832	Uncharacterized protein. (170 aa)
	GATA4	GATA binding protein 4. (402 aa)
	LDB1	LIM domain binding 1. (388 aa)
	LMO3	LIM domain only 3. (76 aa)
	ID4	Inhibitor of DNA binding 4, HLH protein. (132 aa)
	CBFB	Core-binding factor subunit beta. (189 aa)
	ID2	Inhibitor of DNA binding 2. (134 aa)
	ID1	Inhibitor of DNA binding 1, HLH protein. (131 aa)
	MEF2D	Myocyte enhancer factor 2D. (486 aa)
	GATA1	GATA binding protein 1b. (432 aa)
	LHX4	LIM homeobox 4. (312 aa)
	SPTY2D1	SPT2 chromatin protein domain containing 1. (604 aa)
	ID3	Inhibitor of DNA binding 3, HLH protein. (121 aa)
	LDB2	LIM domain binding 2. (248 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (198 aa)
	MYF6	Myogenic factor 6. (272 aa)
	TBX20	T-box transcription factor 20. (441 aa)
	LOC102355848	Uncharacterized protein. (306 aa)
	DBX1	Developing brain homeobox 1. (326 aa)
	TAL1	TAL bHLH transcription factor 1, erythroid differentiation factor. (327 aa)
	MEF2C	Myocyte enhancer factor 2C. (462 aa)
	ISL1	ISL LIM homeobox 1. (356 aa)
	MNX1	Motor neuron and pancreas homeobox 1. (313 aa)
	LOC102346308	NK3 homeobox 3. (267 aa)
	H3AY39_LATCH	Homeobox domain-containing protein. (430 aa)
	LHX9	LIM homeobox 9. (378 aa)
	PAX5	Paired box 5. (189 aa)
	H3AZE1_LATCH	BHLH domain-containing protein. (209 aa)
	RUNX3	RUNX family transcription factor 3. (179 aa)
	MYOCD	Myocardin. (963 aa)
	TCF12	Transcription factor 12. (684 aa)
	FOXF1	Forkhead box F1. (381 aa)
	MYOD1	Myogenic factor. (251 aa)
	GATA5	GATA binding protein 5. (395 aa)
	H3B3V9_LATCH	Myogenic factor. (221 aa)
	MYOG	Myogenin. (242 aa)
	NKX2-5	NK2 homeobox 5. (296 aa)
	POU3F3	POU domain protein. (428 aa)
	LMX1A	LIM homeobox transcription factor 1 alpha. (294 aa)
	MEF2B	Myocyte enhancer factor 2B. (466 aa)
	GATA2	GATA binding protein 2. (467 aa)
	ENSLACP00000017547	annotation not available (174 aa)
	RUNX1-2	RUNX family transcription factor 1. (242 aa)
	LOC102363465	Uncharacterized protein. (344 aa)
	H3B7N1_LATCH	Zgc:171775. (210 aa)
	RUNX1	Runt domain-containing protein. (191 aa)
	TBX18	T-box transcription factor 18. (568 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (443 aa)
	WT1	WT1 transcription factor. (422 aa)
	FLI1	Fli-1 proto-oncogene, ETS transcription factor. (453 aa)
	LHX3	LIM homeobox 3. (313 aa)
	LYL1	BHLH domain-containing protein. (242 aa)
	H3BC83_LATCH	BHLH domain-containing protein. (120 aa)
	RFX4	Regulatory factor X4. (739 aa)
	EN1	Homeobox protein engrailed-like. (271 aa)
	PAX2	Paired box 2. (456 aa)
	EVX1	Even-skipped homeobox 1. (383 aa)
	PRDM12	PR domain zinc finger protein 12; Involved in the positive regulation of histone H3-K9 dimethylation; Belongs to the class V-like SAM-binding methyltransferase superfamily. (354 aa)
	LMCD1	LIM and cysteine rich domains 1. (375 aa)
	H3BFW7_LATCH	BHLH domain-containing protein. (161 aa)
	H3BFZ2_LATCH	BHLH domain-containing protein. (165 aa)
	ZFPM1	Zinc finger protein, FOG family member 1. (1017 aa)
	SPI1	Spi-1 proto-oncogene. (269 aa)
	H3BIS0_LATCH	Uncharacterized protein. (153 aa)
	TCF3	Transcription factor 3. (694 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL1	H3AZE1_LATCH	ENSLACP00000012171	ENSLACP00000015012	Achaete-scute family bHLH transcription factor 1.	BHLH domain-containing protein.	0.422
ASCL1	ID2	ENSLACP00000012171	ENSLACP00000008411	Achaete-scute family bHLH transcription factor 1.	Inhibitor of DNA binding 2.	0.433
ASCL1	ID4	ENSLACP00000012171	ENSLACP00000007640	Achaete-scute family bHLH transcription factor 1.	Inhibitor of DNA binding 4, HLH protein.	0.570
ASCL1	LDB1	ENSLACP00000012171	ENSLACP00000007228	Achaete-scute family bHLH transcription factor 1.	LIM domain binding 1.	0.447
ASCL1	LDB2	ENSLACP00000012171	ENSLACP00000011034	Achaete-scute family bHLH transcription factor 1.	LIM domain binding 2.	0.447
ASCL1	LMX1A	ENSLACP00000012171	ENSLACP00000017022	Achaete-scute family bHLH transcription factor 1.	LIM homeobox transcription factor 1 alpha.	0.446
ASCL1	PHOX2B	ENSLACP00000012171	ENSLACP00000005409	Achaete-scute family bHLH transcription factor 1.	Paired like homeobox 2B.	0.548
ASCL1	TCF12	ENSLACP00000012171	ENSLACP00000016061	Achaete-scute family bHLH transcription factor 1.	Transcription factor 12.	0.735
ASCL1	TCF3	ENSLACP00000012171	ENSLACP00000022252	Achaete-scute family bHLH transcription factor 1.	Transcription factor 3.	0.735
ASCL1	TCF4	ENSLACP00000012171	ENSLACP00000003912	Achaete-scute family bHLH transcription factor 1.	Transcription factor 4.	0.735
CBFB	ERG	ENSLACP00000008364	ENSLACP00000003749	Core-binding factor subunit beta.	ETS transcription factor ERG.	0.557
CBFB	ETS1	ENSLACP00000008364	ENSLACP00000018130	Core-binding factor subunit beta.	ETS proto-oncogene 1, transcription factor.	0.412
CBFB	ETV2	ENSLACP00000008364	ENSLACP00000004587	Core-binding factor subunit beta.	ETS domain-containing protein.	0.412
CBFB	FLI1	ENSLACP00000008364	ENSLACP00000018847	Core-binding factor subunit beta.	Fli-1 proto-oncogene, ETS transcription factor.	0.564
CBFB	GATA1	ENSLACP00000008364	ENSLACP00000010139	Core-binding factor subunit beta.	GATA binding protein 1b.	0.702
CBFB	GATA2	ENSLACP00000008364	ENSLACP00000017265	Core-binding factor subunit beta.	GATA binding protein 2.	0.711
CBFB	GATA4	ENSLACP00000008364	ENSLACP00000006941	Core-binding factor subunit beta.	GATA binding protein 4.	0.555
CBFB	GATA5	ENSLACP00000008364	ENSLACP00000016394	Core-binding factor subunit beta.	GATA binding protein 5.	0.555
CBFB	GATA6	ENSLACP00000008364	ENSLACP00000002849	Core-binding factor subunit beta.	GATA binding protein 6.	0.555
CBFB	H2ZYE4_LATCH	ENSLACP00000008364	ENSLACP00000002415	Core-binding factor subunit beta.	Fli-1 proto-oncogene, ETS transcription factor b.	0.407