(13 nodes) Mixed, incl. LIM interaction domain, and Primitive erythrocyte differentiation network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LMO2	LIM domain only 2. (158 aa)
	H3A5U9_LATCH	LIM domain only 3. (81 aa)
	LDB1	LIM domain binding 1. (388 aa)
	LMO3	LIM domain only 3. (76 aa)
	CBFB	Core-binding factor subunit beta. (189 aa)
	GATA1	GATA binding protein 1b. (432 aa)
	LDB2	LIM domain binding 2. (248 aa)
	TAL1	TAL bHLH transcription factor 1, erythroid differentiation factor. (327 aa)
	RUNX3	RUNX family transcription factor 3. (179 aa)
	GATA2	GATA binding protein 2. (467 aa)
	RUNX1-2	RUNX family transcription factor 1. (242 aa)
	LYL1	BHLH domain-containing protein. (242 aa)
	ZFPM1	Zinc finger protein, FOG family member 1. (1017 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFB	GATA1	ENSLACP00000008364	ENSLACP00000010139	Core-binding factor subunit beta.	GATA binding protein 1b.	0.702
CBFB	GATA2	ENSLACP00000008364	ENSLACP00000017265	Core-binding factor subunit beta.	GATA binding protein 2.	0.711
CBFB	H3A5U9_LATCH	ENSLACP00000008364	ENSLACP00000005020	Core-binding factor subunit beta.	LIM domain only 3.	0.547
CBFB	LDB1	ENSLACP00000008364	ENSLACP00000007228	Core-binding factor subunit beta.	LIM domain binding 1.	0.651
CBFB	LDB2	ENSLACP00000008364	ENSLACP00000011034	Core-binding factor subunit beta.	LIM domain binding 2.	0.651
CBFB	LMO2	ENSLACP00000008364	ENSLACP00000002172	Core-binding factor subunit beta.	LIM domain only 2.	0.767
CBFB	LMO3	ENSLACP00000008364	ENSLACP00000007526	Core-binding factor subunit beta.	LIM domain only 3.	0.547
CBFB	LYL1	ENSLACP00000008364	ENSLACP00000019367	Core-binding factor subunit beta.	BHLH domain-containing protein.	0.705
CBFB	RUNX1-2	ENSLACP00000008364	ENSLACP00000017717	Core-binding factor subunit beta.	RUNX family transcription factor 1.	0.932
CBFB	RUNX3	ENSLACP00000008364	ENSLACP00000015649	Core-binding factor subunit beta.	RUNX family transcription factor 3.	0.932
CBFB	TAL1	ENSLACP00000008364	ENSLACP00000012908	Core-binding factor subunit beta.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.756
CBFB	ZFPM1	ENSLACP00000008364	ENSLACP00000020932	Core-binding factor subunit beta.	Zinc finger protein, FOG family member 1.	0.550
GATA1	CBFB	ENSLACP00000010139	ENSLACP00000008364	GATA binding protein 1b.	Core-binding factor subunit beta.	0.702
GATA1	GATA2	ENSLACP00000010139	ENSLACP00000017265	GATA binding protein 1b.	GATA binding protein 2.	0.755
GATA1	H3A5U9_LATCH	ENSLACP00000010139	ENSLACP00000005020	GATA binding protein 1b.	LIM domain only 3.	0.540
GATA1	LDB1	ENSLACP00000010139	ENSLACP00000007228	GATA binding protein 1b.	LIM domain binding 1.	0.860
GATA1	LDB2	ENSLACP00000010139	ENSLACP00000011034	GATA binding protein 1b.	LIM domain binding 2.	0.645
GATA1	LMO2	ENSLACP00000010139	ENSLACP00000002172	GATA binding protein 1b.	LIM domain only 2.	0.993
GATA1	LMO3	ENSLACP00000010139	ENSLACP00000007526	GATA binding protein 1b.	LIM domain only 3.	0.604
GATA1	LYL1	ENSLACP00000010139	ENSLACP00000019367	GATA binding protein 1b.	BHLH domain-containing protein.	0.539